Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway

Phosphofructokinase-P Modulates P44/42 MAPK Levels in HeLa Cells

(2017) Thyago Rubens Cardim Pires et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Warburg effect: 80 years on

(2016) Michelle Potter et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

News from Tartary: an ethnopharmacological approach to drug and therapeutic discovery

(2016) Nicholas Moore et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Use of NMR Metabolite Profiling andin vivoHypoglycemic Assay for Comparison of Unfractionated Aqueous Leaf Extracts of TwoOcimumSpecies

(2016) Livia Marques Casanova et al.   CHEMISTRY & BIODIVERSITY

Biochemical and molecular mechanisms underlying the chemopreventive efficacy of rosmarinic acid in a rat colon cancer

(2016) Karthikkumar Venkatachalam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antibacterial and antifungal activities of thymol: A brief review of the literature

(2016) Anna Marchese et al.   FOOD CHEMISTRY

Phytochemical Profile and Evaluation of the Biological Activities of Essential Oils Derived from the Greek Aromatic Plant Species Ocimum basilicum, Mentha spicata, Pimpinella anisum and Fortunella margarita

(2016) Eleni Fitsiou et al.   MOLECULES

An overview on the role of dietary phenolics for the treatment of cancers

(2016) Preethi G. Anantharaju et al.   Nutrition Journal

Non-metabolic functions of glycolytic enzymes in tumorigenesis

(2016) X Yu et al.   ONCOGENE

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs

(2016) D. Grahame Hardie et al.   TRENDS IN CELL BIOLOGY

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

(2016) Piero Dalle Pezze et al.   Nature Communications

Anticancer Effects of Rosemary (Rosmarinus officinalis L.) Extract and Rosemary Extract Polyphenols

(2016) Jessy Moore et al.   Nutrients

AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin

(2016) Mei Gao et al.   Oncotarget

Ursolic Acid Induces Apoptosis of Prostate Cancer Cells via the PI3K/Akt/mTOR Pathway

(2015) Yan Meng et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer

(2015) A. H. Rosendahl et al.   CLINICAL CANCER RESEARCH

Cellular and molecular mechanisms of HGF/Met in the cardiovascular system

(2015) S. Gallo et al.   CLINICAL SCIENCE

The Health Benefits of Selected Culinary Herbs and Spices Found in the Traditional Mediterranean Diet

(2015) Allyson Bower et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

(2015) D Grahame Hardie   CURRENT OPINION IN CELL BIOLOGY

Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole

(2015) Cristiane M. Furtado et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Apoptosis Induction byOcimum sanctumExtract in LNCaP Prostate Cancer Cells

(2015) Sivanesan Dhandayuthapani et al.   JOURNAL OF MEDICINAL FOOD

In vitroantioxidant and antiproliferative activities of six international basil cultivars

(2015) Hosam O. Elansary et al.   NATURAL PRODUCT RESEARCH

Anti-Warburg effect of rosmarinic acid via miR-155 in gastric cancer cells

(2015) Zhou Li et al.   Drug Design Development and Therapy

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

(2015) Pierre Sujobert et al.   Cell Reports

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

(2015) Nicole M. Davis et al.   Oncotarget

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

(2014) Simon A. Hawley et al.   BIOCHEMICAL JOURNAL

Identification of chicoric acid as a hypoglycemic agent from Ocimum gratissimum leaf extract in a biomonitoring in vivo study

(2014) Livia Marques Casanova et al.   FITOTERAPIA

Fruit-derived phenolic compounds and pancreatic cancer: Perspectives from Australian native fruits

(2014) Q.V. Vuong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways

(2014) JIA LIU et al.   ONCOLOGY REPORTS

Caffeic Acid Derivatives Inhibit the Growth of Colon Cancer: Involvement of the PI3-K/Akt and AMPK Signaling Pathways

(2014) En-Pei Isabel Chiang et al.   PLoS One

Evaluation of In Vitro Anticancer Activity of Ocimum Basilicum, Alhagi Maurorum, Calendula Officinalis and Their Parasite Cuscuta Campestris

(2014) Mandana Behbahani   PLoS One

Production of anti-cancer triterpene (betulinic acid) from callus cultures of different Ocimum species and its elicitation

(2014) Harshita Pandey et al.   PROTOPLASMA

Agonist antibodies activating the Met receptor protect cardiomyoblasts from cobalt chloride-induced apoptosis and autophagy

(2014) S Gallo et al.   Cell Death & Disease

The Role of Phenolic Compounds in the Fight against Cancer – A Review

(2013) Márcio Carocho et al.   Anti-Cancer Agents in Medicinal Chemistry

Ocimum sanctum Linn. (Tulsi)

(2013) Piyali Bhattacharyya et al.   ANTI-CANCER DRUGS

Breast cancer statistics, 2013

(2013) Carol DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Ocimum gratissimumretards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases

(2013) Pratima Nangia-Makker et al.   CANCER BIOLOGY & THERAPY

Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya

(2013) Dominic O. Ochwang’i et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ocimum SanctumL (Holy Basil or Tulsi) and Its Phytochemicals in the Prevention and Treatment of Cancer

(2013) Manjeshwar Shrinath Baliga et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Chicoric Acid Is an Antioxidant Molecule That Stimulates AMP Kinase Pathway in L6 Myotubes and Extends Lifespan in Caenorhabditis elegans

(2013) Audrey Schlernitzauer et al.   PLoS One

p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake

(2012) Yossi Dagon et al.   Cell Metabolism

Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis

(2012) Yu-Ling Tsai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Clotrimazole Preferentially Inhibits Human Breast Cancer Cell Proliferation, Viability and Glycolysis

(2012) Cristiane M. Furtado et al.   PLoS One

Effects of Lipoic Acid, Caffeic Acid and a Synthesized Lipoyl-Caffeic Conjugate on Human Hepatoma Cell Lines

(2011) Eliana Guerriero et al.   MOLECULES

Chemical composition of the essential oil from basil (Ocimum basilicumLinn.) and itsin vitrocytotoxicity against HeLa and HEp-2 human cancer cell lines and NIH 3T3 mouse embryonic fibroblasts

(2011) Poonkodi Kathirvel et al.   NATURAL PRODUCT RESEARCH

Identification of Filamin A as a BRCA1-interacting protein required for efficient DNA repair

(2010) Aneliya Velkova et al.   CELL CYCLE

Inhibitory effect of caffeic acid on cancer cell proliferation by oxidative mechanism in human HT-1080 fibrosarcoma cell line

(2010) N. Rajendra Prasad et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Differential expression of phosphofructokinase-1 isoforms correlates with the glycolytic efficiency of breast cancer cells

(2010) Patricia Zancan et al.   MOLECULAR GENETICS AND METABOLISM

The genetic basis of kidney cancer: a metabolic disease

(2010) W. Marston Linehan et al.   Nature Reviews Urology

Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity

(2008) Guilherme A. Spitz et al.   BIOCHEMICAL PHARMACOLOGY

Variation of Ursolic Acid Content in Eight Ocimum Species from Northeastern Brazil

(2008) M. Goretti Silva et al.   MOLECULES