Ursolic Acid Induces Apoptosis of Prostate Cancer Cells via the PI3K/Akt/mTOR Pathway

Emerging roles of radioresistance in prostate cancer metastasis and radiation therapy

(2014) Lei Chang et al.   CANCER AND METASTASIS REVIEWS

Penta-O-galloyl-β-d-glucose Suppresses EGF-Induced eIF3i Expression through Inhibition of the PI3K/AKT/mTOR Pathway in Prostate Cancer Cells

(2014) Victor Chia-Hsiang Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Clove Extract Inhibits Tumor Growth and Promotes Cell Cycle Arrest and Apoptosis

(2014) Haizhou Liu et al.   ONCOLOGY RESEARCH

Inhibition of Wnt/β-catenin signaling mediates ursolic acid-induced apoptosis in PC-3 prostate cancer cells

(2014) Ji-Hyuk Park et al.   Pharmacological Reports

NSK-01105 inhibits proliferation and induces apoptosis of prostate cancer cells by blocking the Raf/MEK/ERK and PI3K/Akt/mTOR signal pathways

(2014) Pengfei Yu et al.   TUMOR BIOLOGY

PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways

(2014) L Chang et al.   Cell Death & Disease

Current Approaches, Challenges and Future Directions for Monitoring Treatment Response in Prostate Cancer

(2014) T.J. Wallace et al.   Journal of Cancer

Ursolic acid inhibits tumor angiogenesis and induces apoptosis through mitochondrial-dependent pathway in Ehrlich ascites carcinoma tumor

(2013) Sarita Saraswati et al.   CHEMICO-BIOLOGICAL INTERACTIONS

TGF-β Effects on Prostate Cancer Cell Migration and Invasion Are Mediated by PGE2through Activation of PI3K/AKT/mTOR Pathway

(2013) BaoHan T. Vo et al.   ENDOCRINOLOGY

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

(2013) Jie Ni et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ursolic acid sensitizes prostate cancer cells to TRAIL-mediated apoptosis

(2012) Seoung Woo Shin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells

(2012) Youness Limami et al.   BIOCHIMIE

Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways

(2012) Su Jung Oh et al.   ENDOCRINE-RELATED CANCER

Ursolic Acid Inhibits the Initiation, Progression of Prostate Cancer and Prolongs the Survival of TRAMP Mice by Modulating Pro-Inflammatory Pathways

(2012) Muthu K. Shanmugam et al.   PLoS One

Grape Proanthocyanidin Inhibit Pancreatic Cancer Cell Growth In Vitro and In Vivo through Induction of Apoptosis and by Targeting the PI3K/Akt Pathway

(2012) Ram Prasad et al.   PLoS One

Ursolic acid causes DNA-damage, P53-mediated, mitochondria- and caspase-dependent human endothelial cell apoptosis, and accelerates atherosclerotic plaque formation in vivo

(2011) Barbara Messner et al.   ATHEROSCLEROSIS

Autophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells

(2011) Seoung Woo Shin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy

(2011) P N Kelly et al.   CELL DEATH AND DIFFERENTIATION

Dual Inhibitors of PI3K/mTOR or mTOR-Selective Inhibitors: Which Way Shall We Go?

(2011) D. A. Sabbah et al.   CURRENT MEDICINAL CHEMISTRY

Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

(2011) Andreas Strasser et al.   EMBO JOURNAL

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model

(2011) Muthu K. Shanmugam et al.   INTERNATIONAL JOURNAL OF CANCER

Ursolic acid and its esters: occurrence in cranberries and other Vaccinium fruit and effects on matrix metalloproteinase activity in DU145 prostate tumor cells

(2011) Miwako Kondo et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Ursolic Acid Triggers Apoptosis and Bcl-2 Downregulation in MCF-7 Breast Cancer Cells

(2009) E. Kassi et al.   CANCER INVESTIGATION

Apoptosis induction of human leukemia U937 cells by gomisin N, a dibenzocyclooctadiene lignan, isolated from Schizandra chinensis Baill

(2009) Jong-Hwan Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises

(2008) Timothy A Yap et al.   CURRENT OPINION IN PHARMACOLOGY