Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing

Discovery ofscmRas a global regulator of secondary metabolism and virulence inBurkholderia thailandensisE264

(2017) Dainan Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Complex Quorum Sensing Circuitry of Burkholderia thailandensis Is Both Hierarchically and Homeostatically Organized

(2017) Servane Le Guillouzer et al.   mBio

Detection of Burkholderia pseudomallei toxin-mediated inhibition of protein synthesis using a Caenorhabditis elegans ugt–29 biosensor

(2016) Rui-Rui Wong et al.   Scientific Reports

Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis

(2016) Direk Limmathurotsakul et al.   Nature Microbiology

Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei

(2015) Madeleine G. Moule et al.   INFECTION AND IMMUNITY

A Burkholderia thailandensis Acyl-Homoserine Lactone-Independent Orphan LuxR Homolog That Activates Production of the Cytotoxin Malleilactone

(2015) Thao T. Truong et al.   JOURNAL OF BACTERIOLOGY

Comprehensive identification of virulence factors required for respiratory melioidosis using Tn-seq mutagenesis

(2015) Maria G. Gutierrez et al.   Frontiers in Cellular and Infection Microbiology

Cross-Species Comparison of the Burkholderia pseudomallei, Burkholderia thailandensis, and Burkholderia mallei Quorum-Sensing Regulons

(2014) C. D. Majerczyk et al.   JOURNAL OF BACTERIOLOGY

Global Analysis of the Burkholderia thailandensis Quorum Sensing-Controlled Regulon

(2014) C. Majerczyk et al.   JOURNAL OF BACTERIOLOGY

The Chemical Arsenal of Burkholderia pseudomallei Is Essential for Pathogenicity

(2014) John B. Biggins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-throughput platform for the discovery of elicitors of silent bacterial gene clusters

(2014) M. R. Seyedsayamdost   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virulence of Burkholderia mallei Quorum-Sensing Mutants

(2013) Charlotte Majerczyk et al.   INFECTION AND IMMUNITY

Bacterial LuxR solos have evolved to respond to different molecules including signals from plants

(2013) Hitendra K. Patel et al.   Frontiers in Plant Science

Genomics-Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human PathogenicBurkholderiaSpecies

(2012) Jakob Franke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Malleilactone, a Polyketide Synthase-Derived Virulence Factor Encoded by the Cryptic Secondary Metabolome of Burkholderia pseudomallei Group Pathogens

(2012) John B. Biggins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Burkholderia pseudomalleikillsCaenorhabditis elegansthrough virulence mechanisms distinct from intestinal lumen colonization

(2012) Soon-Keat Ooi et al.   Virulence

Burkholderia pseudomallei Known Siderophores and Hemin Uptake Are Dispensable for Lethal Murine Melioidosis

(2012) Brian H. Kvitko et al.   PLoS Neglected Tropical Diseases

The Burkholderia pseudomallei ΔasdMutant Exhibits Attenuated Intracellular Infectivity and Imparts Protection against Acute Inhalation Melioidosis in Mice

(2011) Michael H. Norris et al.   INFECTION AND IMMUNITY

Metabolites from the Induced Expression of Cryptic Single Operons Found in the Genome of Burkholderia pseudomallei

(2011) John B. Biggins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Octanoylhomoserine lactone signalling mediated by the BpsI-BpsR quorum sensing system plays a major role in biofilm formation of Burkholderia pseudomallei

(2011) A. M. Gamage et al.   MICROBIOLOGY-SGM

The Serratia LuxR family regulator CarR39006 activates transcription independently of cognate quorum sensing signals

(2011) Simon Poulter et al.   MOLECULAR MICROBIOLOGY

Acyldepsipeptide HDAC Inhibitor Production Induced inBurkholderia thailandensis

(2011) John B. Biggins et al.   ORGANIC LETTERS

Complete Killing of Caenorhabditis elegans by Burkholderia pseudomallei Is Dependent on Prolonged Direct Association with the Viable Pathogen

(2011) Song-Hua Lee et al.   PLoS One

A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A

(2011) A. Cruz-Migoni et al.   SCIENCE

Stable, Site-Specific Fluorescent Tagging Constructs Optimized for Burkholderia Species

(2010) M. H. Norris et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Burkholderia pseudomallei  purM Mutant Is Avirulent in Immunocompetent and Immunodeficient Animals: Candidate Strain for Exclusion from Select-Agent Lists

(2010) K. L. Propst et al.   INFECTION AND IMMUNITY

Quorum-Sensing-Regulated Bactobolin Production byBurkholderia thailandensisE264

(2010) Mohammad R. Seyedsayamdost et al.   ORGANIC LETTERS

LuxR homolog-independent gene regulation by acyl-homoserine lactones in Pseudomonas aeruginosa

(2010) S. Chugani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational Analysis of Burkholderia thailandensis Quorum Sensing and Self-Aggregation

(2009) J. R. Chandler et al.   JOURNAL OF BACTERIOLOGY

Roles and Interactions of Burkholderia pseudomallei BpsIR Quorum-Sensing System Determinants

(2008) P. Kiratisin et al.   JOURNAL OF BACTERIOLOGY