Metabolomics-on-a-chip approach to study hepatotoxicity of DDT, permethrin and their mixtures

Effects of DDT and permethrin on rat hepatocytes cultivated in microfluidic biochips: Metabolomics and gene expression study

(2018) Rachid Jellali et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Insecticide resistance in malaria vectors along the Thailand-Myanmar border

(2017) Victor Chaumeau et al.   Parasites & Vectors

Pyrethroids and DDT tolerance ofAnopheles gambiaes.l. from Sengerema District, an area of intensive pesticide usage in north-western Tanzania

(2017) Anitha Philbert et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Permethrin is a potential thyroid-disrupting chemical: In vivo and in silico envidence

(2016) Wenqing Tu et al.   AQUATIC TOXICOLOGY

Long-term human primary hepatocyte cultures in a microfluidic liver biochip show maintenance of mRNA levels and higher drug metabolism compared with Petri cultures

(2016) Rachid Jellali et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Effects of pesticide mixtures in human and animal models: An update of the recent literature

(2016) V. Rizzati et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Toxicological effects of benzo(a)pyrene, DDT and their mixture on the green mussel Perna viridis revealed by proteomic and metabolomic approaches

(2016) Qinqin Song et al.   CHEMOSPHERE

Metabolite Profiling to Monitor Organochlorine Pesticide Exposure in HepG2 Cell Culture

(2016) Martha Zuluaga et al.   CHROMATOGRAPHIA

The metabolic fingerprint of p,p′-DDE and HCB exposure in humans

(2016) Samira Salihovic et al.   ENVIRONMENT INTERNATIONAL

Permethrin-induced oxidative stress and toxicity and metabolism. A review

(2016) Xu Wang et al.   ENVIRONMENTAL RESEARCH

Temporal Trends of Insecticide Concentrations in Carpet Dust in California from 2001 to 2006

(2016) Robert B. Gunier et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Spatial and temporal assessment of environmental contaminants in water, sediments and fish of the Salton Sea and its two primary tributaries, California, USA, from 2002 to 2012

(2016) Elvis Genbo Xu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Liver and kidney cells cultures in a new perfluoropolyether biochip

(2016) Rachid Jellali et al.   SENSORS AND ACTUATORS B-CHEMICAL

PBPK modeling of the cis - and trans -permethrin isomers and their major urinary metabolites in rats

(2016) Marie-Emilie Willemin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Toxic effects of male Perna viridis gonad exposed to BaP, DDT and their mixture: A metabolomic and proteomic study of the underlying mechanism

(2016) Qinqin Song et al.   TOXICOLOGY LETTERS

Investigation of acetaminophen toxicity in HepG2/C3a microscale cultures using a system biology model of glutathione depletion

(2015) Eric Leclerc et al.   CELL BIOLOGY AND TOXICOLOGY

Metabolomic profiling of permethrin-treated Drosophila melanogaster identifies a role for tryptophan catabolism in insecticide survival

(2015) Robert A. Brinzer et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Sertoli cell as a model in male reproductive toxicology: Advantages and disadvantages

(2015) Mariana M. S. Reis et al.   JOURNAL OF APPLIED TOXICOLOGY

In vitro human metabolism of permethrin isomers alone or as a mixture and the formation of the major metabolites in cryopreserved primary hepatocytes

(2015) M.-E. Willemin et al.   TOXICOLOGY IN VITRO

Potential Input From Metabolomics for Exploring and Understanding the Links Between Environment and Health

(2014) Nathalie Bonvallot et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

NMR-based metabolomics approach to study the toxicity of lambda-cyhalothrin to goldfish (Carassius auratus)

(2013) Minghui Li et al.   AQUATIC TOXICOLOGY

Investigation of expression and activity levels of primary rat hepatocyte detoxication genes under various flow rates and cell densities in microfluidic biochips

(2013) Régis Baudoin et al.   BIOTECHNOLOGY PROGRESS

A metabonomic investigation of the effects of 60days exposure of rats to two types of pyrethroid insecticides

(2013) Yu-Jie Liang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Concerted changes in N and C primary metabolism in alfalfa (Medicago sativa) under water restriction

(2013) Iker Aranjuelo et al.   JOURNAL OF EXPERIMENTAL BOTANY

Metabolomic Analysis of the Effects of Chronic Arsenic Exposure in a Mouse Model of Diet-Induced Fatty Liver Disease

(2013) Xue Shi et al.   JOURNAL OF PROTEOME RESEARCH

The PERICLES research program: An integrated approach to characterize the combined effects of mixtures of pesticide residues to which the French population is exposed

(2013) A. Crépet et al.   TOXICOLOGY

Metabolomics-on-a-Chip and Predictive Systems Toxicology in Microfluidic Bioartificial Organs

(2012) Laetitia Shintu et al.   ANALYTICAL CHEMISTRY

The in vivo estrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin

(2012) Susanne M. Brander et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Organochlorine pesticides induce epithelial to mesenchymal transition of human primary cultured hepatocytes

(2012) Nathalie Zucchini-Pascal et al.   FOOD AND CHEMICAL TOXICOLOGY

Effects of DDT and triclosan on tumor-cell binding capacity and cell-surface protein expression of human natural killer cells

(2012) Tasia Hurd-Brown et al.   JOURNAL OF APPLIED TOXICOLOGY

Parallelized microfluidic biochips in multi well plate applied to liver tissue engineering

(2012) Régis Baudoin et al.   SENSORS AND ACTUATORS B-CHEMICAL

Metabolomics-on-a-Chip of Hepatotoxicity Induced by Anticancer Drug Flutamide and Its Active Metabolite Hydroxyflutamide Using HepG2/C3a Microfluidic Biochips

(2012) Leila Choucha Snouber et al.   TOXICOLOGICAL SCIENCES

Toxic effects of pesticide mixtures at a molecular level: Their relevance to human health

(2012) Antonio F. Hernández et al.   TOXICOLOGY

Persistent organochlorinated pesticides and mechanisms of their toxicity

(2012) Ezra J. Mrema et al.   TOXICOLOGY

Applying biofluid metabonomic techniques to analyze the combined subchronic toxicity of propoxur and permethrin in rats

(2012) Yu-Jie Liang et al.   Bioanalysis

Microfluidic cell culture models for tissue engineering

(2011) Niraj K Inamdar et al.   CURRENT OPINION IN BIOTECHNOLOGY

Permethrin exposure during puberty has the potential to enantioselectively induce reproductive toxicity in mice

(2011) Yuanxiang Jin et al.   ENVIRONMENT INTERNATIONAL

Predictive toxicology using systemic biology and liver microfluidic “on chip” approaches: Application to acetaminophen injury

(2011) Jean-Matthieu Prot et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Behavior of HepG2/C3A cell cultures in a microfluidic bioreactor

(2010) Régis Baudoin et al.   BIOCHEMICAL ENGINEERING JOURNAL

Effects of dermal sub-chronic exposure of pubescent male rats to permethrin (PRMT) on the histological structures of genital tract, testosterone and lipoperoxidation

(2010) Chargui Issam et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

GC-MS-based metabolomics reveals mechanism of action for hydrazine induced hepatotoxicity in rats

(2010) Kiyoko Bando et al.   JOURNAL OF APPLIED TOXICOLOGY

NMR-based metabonomic analysis of the hepatotoxicity induced by combined exposure to PCBs and TCDD in rats

(2010) Chunfeng Lu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Malaria Control Insecticide Residues in Breast Milk: The Need to Consider Infant Health Risks

(2009) Hindrik Bouwman et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Permethrin induces lymphocyte DNA lesions at both Endo III and Fpg sites and changes in monocyte respiratory burst in rats

(2009) Rosita Gabbianelli et al.   JOURNAL OF APPLIED TOXICOLOGY

Risk assessment of mixtures of pesticides. Current approaches and future strategies

(2009) Trine Klein Reffstrup et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Induction of hepatic estrogen-responsive gene transcription by permethrin enantiomers in male adult zebrafish

(2008) Yuanxiang Jin et al.   AQUATIC TOXICOLOGY

The Synergistic Toxicity of Pesticide Mixtures: Implications for Risk Assessment and the Conservation of Endangered Pacific Salmon

(2008) Cathy A. Laetz et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Human semen quality and sperm DNA damage in relation to urinary metabolites of pyrethroid insecticides

(2008) J. D. Meeker et al.   HUMAN REPRODUCTION

1H NMR and GC/MS metabolomics of earthworm responses to sub-lethal DDT and endosulfan exposure

(2008) Jennifer R. McKelvie et al.   Metabolomics

Toxic effects of DDT and methyl mercury on the hepatocytes from Hoplias malabaricus

(2008) F. Filipak Neto et al.   TOXICOLOGY IN VITRO