The Recent De Novo Origin of Protein C-Termini

Yeast Alcohol Dehydrogenase Structure and Catalysis

(2014) Savarimuthu Baskar Raj et al.   BIOCHEMISTRY

Programmed Translational Readthrough Generates Antiangiogenic VEGF-Ax

(2014) Sandeepa M. Eswarappa et al.   CELL

A High-Definition View of Functional Genetic Variation from Natural Yeast Genomes

(2014) Anders Bergström et al.   MOLECULAR BIOLOGY AND EVOLUTION

Evidence of efficient stop codon readthrough in four mammalian genes

(2014) Gary Loughran et al.   NUCLEIC ACIDS RESEARCH

Origin and Spread of de Novo Genes in Drosophila melanogaster Populations

(2014) L. Zhao et al.   SCIENCE

X-ray structure of a CDP-alcohol phosphatidyltransferase membrane enzyme and insights into its catalytic mechanism

(2014) Przemyslaw Nogly et al.   Nature Communications

Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes

(2014) Nicholas T. Ingolia et al.   Cell Reports

Genome-wide Translational Changes Induced by the Prion [PSI+]

(2014) Agnès Baudin-Baillieu et al.   Cell Reports

Translation of Small Open Reading Frames within Unannotated RNA Transcripts in Saccharomyces cerevisiae

(2014) Jenna E. Smith et al.   Cell Reports

Ribosomal Readthrough at a Short UGA Stop Codon Context Triggers Dual Localization of Metabolic Enzymes in Fungi and Animals

(2014) Alina C. Stiebler et al.   PLoS Genetics

NCYM, a Cis-Antisense Gene of MYCN, Encodes a De Novo Evolved Protein That Inhibits GSK3β Resulting in the Stabilization of MYCN in Human Neuroblastomas

(2014) Yusuke Suenaga et al.   PLoS Genetics

Long non-coding RNAs as a source of new peptides

(2014) Jorge Ruiz-Orera et al.   eLife

New Gene Evolution: Little Did We Know

(2013) Manyuan Long et al.   Annual Review of Genetics

Phylogenetic patterns of emergence of new genes support a model of frequent de novo evolution

(2013) Rafik Neme et al.   BMC GENOMICS

Structure and Subunit Topology of the INO80 Chromatin Remodeler and Its Nucleosome Complex

(2013) Alessandro Tosi et al.   CELL

Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins

(2013) Mitchell Guttman et al.   CELL

Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast

(2013) D. A. Skelly et al.   GENOME RESEARCH

De Novo ORFs in Drosophila Are Important to Organismal Fitness and Evolved Rapidly from Previously Non-coding Sequences

(2013) Josephine A. Reinhardt et al.   PLoS Genetics

Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster

(2013) Joshua G Dunn et al.   eLife

Origins of New Genes and Evolution of Their Novel Functions

(2012) Yun Ding et al.   Annual Review of Ecology Evolution and Systematics

L-MPZ, a Novel Isoform of Myelin P0, Is Produced by Stop Codon Readthrough

(2012) Yoshihide Yamaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryptic peroxisomal targeting via alternative splicing and stop codon read-through in fungi

(2012) Johannes Freitag et al.   NATURE

Prions are a common mechanism for phenotypic inheritance in wild yeasts

(2012) Randal Halfmann et al.   NATURE

De Novo Origin of Protein-Coding Genes in Murine Rodents

(2012) Daniel N. Murphy et al.   PLoS One

Interactions between the nucleosome histone core and Arp8 in the INO80 chromatin remodeling complex

(2012) M. Saravanan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hominoid-Specific De Novo Protein-Coding Genes Originating from Long Non-Coding RNAs

(2012) Chen Xie et al.   PLoS Genetics

Evolutionary origins of Brassicaceae specific genes in Arabidopsis thaliana

(2011) Mark TA Donoghue et al.   BMC EVOLUTIONARY BIOLOGY

Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin

(2011) Sebastian Fenn et al.   EMBO JOURNAL

De novo origin of new genes with introns inPlasmodium vivax

(2011) Zefeng Yang et al.   FEBS LETTERS

Putatively Noncoding Transcripts Show Extensive Association with Ribosomes

(2011) Benjamin A. Wilson et al.   Genome Biology and Evolution

Widespread Polymorphism in the Positions of Stop Codons in Drosophila melanogaster

(2011) Yuh Chwen G. Lee et al.   Genome Biology and Evolution

Evidence of abundant stop codon readthrough in Drosophila and other metazoa

(2011) I. Jungreis et al.   GENOME RESEARCH

The evolutionary origin of orphan genes

(2011) Diethard Tautz et al.   NATURE REVIEWS GENETICS

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

Assessment of Inactivating Stop Codon Mutations in Forty Saccharomyces cerevisiae Strains: Implications for [PSI+] Prion- Mediated Phenotypes

(2011) David A. Fitzpatrick et al.   PLoS One

De Novo Origin of Human Protein-Coding Genes

(2011) Dong-Dong Wu et al.   PLoS Genetics

A de novo originated gene depresses budding yeast mating pathway and is repressed by the protein encoded by its antisense strand

(2010) Dan Li et al.   CELL RESEARCH

Evolutionary novelties

(2010) Günter P. Wagner et al.   CURRENT BIOLOGY

Evolution of Prokaryotic Genes by Shift of Stop Codons

(2010) Anna A. Vakhrusheva et al.   JOURNAL OF MOLECULAR EVOLUTION

Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions

(2010) Shenping Wu et al.   PLoS One

A Human-Specific De Novo Protein-Coding Gene Associated with Human Brain Functions

(2010) Chuan-Yun Li et al.   PLoS Computational Biology

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Local alignment of two-base encoded DNA sequence

(2009) Nils Homer et al.   BMC BIOINFORMATICS

Darwinian alchemy: Human genes from noncoding DNA

(2009) A. Siepel   GENOME RESEARCH

Recent de novo origin of human protein-coding genes

(2009) D. G. Knowles et al.   GENOME RESEARCH

Large-scale analysis of exonized mammalian-wide interspersed repeats in primate genomes

(2009) Lan Lin et al.   HUMAN MOLECULAR GENETICS

Molecular Evolution of GYPC: Evidence for Recent Structural Innovation and Positive Selection in Humans

(2009) Jason A. Wilder et al.   MOLECULAR BIOLOGY AND EVOLUTION

The nature of the globular- to fibrous-actin transition

(2009) Toshiro Oda et al.   NATURE

Population genomics of domestic and wild yeasts

(2009) Gianni Liti et al.   NATURE

A Rice Gene of De Novo Origin Negatively Regulates Pathogen-Induced Defense Response

(2009) Wenfei Xiao et al.   PLoS One

Length Variations amongst Protein Domain Superfamilies and Consequences on Structure and Function

(2009) Sankaran Sandhya et al.   PLoS One

BFAST: An Alignment Tool for Large Scale Genome Resequencing

(2009) Nils Homer et al.   PLoS One

Global discovery of primate-specific genes in the human genome

(2009) S.-K. Tay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

The alcohol dehydrogenases ofSaccharomyces cerevisiae: a comprehensive review

(2008) Olga de Smidt et al.   FEMS YEAST RESEARCH

De Novo Origination of a New Protein-Coding Gene in Saccharomyces cerevisiae

(2008) J. Cai et al.   GENETICS

On the origin of new genes in Drosophila

(2008) Q. Zhou et al.   GENOME RESEARCH

Origin of Primate Orphan Genes: A Comparative Genomics Approach

(2008) M. Toll-Riera et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Jpred 3 secondary structure prediction server

(2008) C. Cole et al.   NUCLEIC ACIDS RESEARCH

Population genomics of the wild yeast Saccharomyces paradoxus: Quantifying the life cycle

(2008) I. J. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Transcriptional Landscape of the Yeast Genome Defined by RNA Sequencing

(2008) U. Nagalakshmi et al.   SCIENCE

CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations

(2008) Sankaran Sandhya et al.   BMC STRUCTURAL BIOLOGY

Fusion and Fission of Genes Define a Metric between Fungal Genomes

(2008) Pascal Durrens et al.   PLoS Computational Biology