Does the Genetic Feature of the Chinese Tree Shrew (Tupaia belangeri chinensis) Support Its Potential as a Viable Model for Alzheimer’s Disease Research?

Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease

(2017) Melissa K. Edler et al.   NEUROBIOLOGY OF AGING

The RNA editome of Macaca mulatta and functional characterization of RNA editing in mitochondria

(2017) Ling-Qun Ye et al.   Science Bulletin

Amyloid-β Peptide and Oligomers in the Brain and Cerebrospinal Fluid of Aged Canines

(2017) Elizabeth Head et al.   JOURNAL OF ALZHEIMERS DISEASE

Injection of Aβ1-40 into hippocampus induced cognitive lesion associated with neuronal apoptosis and multiple gene expressions in the tree shrew

(2016) Na Lin et al.   APOPTOSIS

Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring

(2016) Chao-Hui Li et al.   CELL RESEARCH

Genome Editing with CRISPR-Cas9: Can It Get Any Better?

(2016) Maximilian Haeussler et al.   Journal of Genetics and Genomics

Upregulation of Aβ42 in the Brain and Bodily Fluids of Rhesus Monkeys with Aging

(2016) Qiao Zhao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Topology of ON and OFF inputs in visual cortex enables an invariant columnar architecture

(2016) Kuo-Sheng Lee et al.   NATURE

Comparative pathobiology of β-amyloid and the unique susceptibility of humans to Alzheimer's disease

(2016) Rebecca F. Rosen et al.   NEUROBIOLOGY OF AGING

Quantitative protein profiling of hippocampus during human aging

(2016) Benhong Xu et al.   NEUROBIOLOGY OF AGING

Whole-brain mapping of afferent projections to the bed nucleus of the stria terminalis in tree shrews

(2016) Rong-Jun Ni et al.   NEUROSCIENCE

Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew

(2016) Ling Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation

(2015) Ling-Yan Su et al.   Autophagy

Characterization of a MAVS ortholog from the Chinese tree shrew (Tupaia belangeri chinensis)

(2015) Ling Xu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The 3rd Symposium on Animal Models of Primates – The Application of Non-Human Primates to Basic Research and Translational Medicine

(2015) Yong-Gang Yao et al.   Journal of Genetics and Genomics

Age-associated evolution of plasmatic amyloid in mouse lemur primates: relationship with intracellular amyloid deposition

(2015) Maggie Roy et al.   NEUROBIOLOGY OF AGING

Correspondence between Resting-State Activity and Brain Gene Expression

(2015) Guang-Zhong Wang et al.   NEURON

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Immunohistochemical mapping of neuropeptide Y in the tree shrew brain

(2014) Rong-Jun Ni et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Distribution of vasopressin, oxytocin and vasoactive intestinal polypeptide in the hypothalamus and extrahypothalamic regions of tree shrews

(2014) R.-J. Ni et al.   NEUROSCIENCE

Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew

(2014) Yu Fan et al.   Scientific Reports

Using the zebrafish model for Alzheimer’s disease research

(2014) Morgan Newman et al.   Frontiers in Genetics

On the Relation Between Receptive Field Structure and Stimulus Selectivity in the Tree Shrew Primary Visual Cortex

(2013) Julia Veit et al.   CEREBRAL CORTEX

Quetiapine Modulates Conditioned Anxiety and Alternation Behavior in Alzheimer’s Transgenic Mice

(2013) Adrien Tempier et al.   Current Alzheimer Research

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome of the Chinese tree shrew

(2013) Yu Fan et al.   Nature Communications

Evaluating the Phylogenetic Position of Chinese Tree Shrew (Tupaia belangeri chinensis) Based on Complete Mitochondrial Genome: Implication for Using Tree Shrew as an Alternative Experimental Animal to Primates in Biomedical Research

(2012) Ling Xu et al.   Journal of Genetics and Genomics

Somatostatin-immunoreactive senile plaque-like structures in the frontal cortex and nucleus accumbens of aged tree shrews and Japanese macaques

(2012) Akiko Yamashita et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Animal models in the drug discovery pipeline for Alzheimer's disease

(2011) Debby Van Dam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Extensive Characterization of Tupaia belangeri Neuropeptidome Using an Integrated Mass Spectrometric Approach

(2011) Filomena Petruzziello et al.   JOURNAL OF PROTEOME RESEARCH

A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

The evolution of gene expression levels in mammalian organs

(2011) David Brawand et al.   NATURE

Cerebral amyloid β(42) deposits and microvascular pathology in ageing baboons

(2011) M. Ndung'u et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

β-Secretase-1 elevation in aged monkey and Alzheimer’s disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation

(2010) Yan Cai et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Natural Non-Trasgenic Animal Models for Research in Alzheimers Disease

(2009) Manuel Sarasa et al.   Current Alzheimer Research

Searching for new animal models of Alzheimer′s disease

(2009) Roberta Epis et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Age-associated cerebral atrophy in mouse lemur primates

(2009) Audrey Kraska et al.   NEUROBIOLOGY OF AGING

Evolution of the Aging Brain Transcriptome and Synaptic Regulation

(2008) Patrick M. Loerch et al.   PLoS One