4.2 Review

Biogeochemical Cycle, Occurrence and Biological Treatments of Polycyclic Aromatic Hydrocarbons (PAHs)

Journal

Publisher

SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1007/s40995-017-0393-8

Keywords

Abiotic factors; Biodegradation; Biogeochemistry; Biotic factors; PAHs; Toxicity

Ask authors/readers for more resources

Polycyclic aromatic hydrocarbons are responsible for contaminating environmental compartments around the world, imposing risk associated with human health and ecosystem pollution. Emissions from anthropogenic activities predominate; nevertheless, open burning, volcanic activities, and natural losses of petroleum deposits are prominent natural sources. Different physical and chemical treatment technologies have been developed and tested for the removal of PAHs, but the use of biological entities was found most favourable for adaptation at industrial scale. This review can help to understand the mobility of PAHs in the environment. Focus of this review is on identifying processes through which PAHs are added to environment, their biogeochemical cycles, biodegradation, environmental and substrate-specific factors affecting biodegradation. Further studies related to different bioprocesses linked with remediation and removal methodologies along with factors affecting the treatment have also been brought into consideration. This review brings together inter-disciplinary aspects and understanding for PAHs, to which no previous review has focused.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Biochemistry & Molecular Biology

New lead compounds identification against KRas mediated cancers through pharmacophore-based virtual screening and in vitro assays

Mehreen Ghufran, Ashfaq Ur Rehman, Muhammad Ayaz, Zaheer Ul-Haq, Reaz Uddin, Syed Sikander Azam, Abdul Wadood

Summary: This study used computer-aided drug designing approaches and experimental methods to find new and potential anti-cancer drugs. A pharmacophore model was developed and used for virtual screening, resulting in the identification of compounds with good interactions with the target protein. The results were further validated through molecular dynamics simulation analysis.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2023)

Article Multidisciplinary Sciences

Effect of Soil Amendments on the Enzymatic Profile of Soil when Nicotiana alata L. and Petunia hybrida L. were Irrigated with Synthetic Heavy Metal-contaminated Wastewater

Aqib Hassan Ali Khan, Syedah Zoya Kazmi, Cyrus Raza Mirza, Tayyab Ashfaq Butt, Nida Gul, Roco Barros, Sohail Yousaf, Mazhar Iqbal Pakistan

Summary: This study investigates the improvement of soil enzyme activities and finds that the combination of 5% moss, compost, and biochar can effectively increase enzyme activities.

CHIANG MAI JOURNAL OF SCIENCE (2023)

Review Environmental Sciences

Sustainability of phytoremediation: Post-harvest stratagems and economic opportunities for the produced metals contaminated biomass

Aqib Hassan Ali Khan, Amna Kiyani, Mario Santiago-Herrera, Jesus Ibanez, Sohail Yousaf, Mazhar Iqbal, Sonia Martel-Martin, Rocio Barros

Summary: Heavy metals (HMs) are non-biodegradable and can be transferred from environmental matrices to plants through phytoremediation. Phytoremediation of HMs has advantages such as biophilia and carbon neutrality compared to other remediation methods. Studies also suggest that phytoremediation is more sustainable based on life cycle assessment. However, proper management of HMs contaminated biomass after phytoremediation is a challenge, as it can reintroduce HMs into the environment. This review discusses a sustainable phytoremediation strategy using life cycle assessment and various biomass management options.

JOURNAL OF ENVIRONMENTAL MANAGEMENT (2023)

Article Biotechnology & Applied Microbiology

In-Silico Lead Druggable Compounds Identification against SARS COVID-19 Main Protease Target from In-House, Chembridge and Zinc Databases by Structure-Based Virtual Screening, Molecular Docking and Molecular Dynamics Simulations

Mehreen Ghufran, Mehran Ullah, Haider Ali Khan, Sabreen Ghufran, Muhammad Ayaz, Muhammad Siddiq, Syed Qamar Abbas, Syed Shams ul Hassan, Simona Bungau

Summary: During the SARS-CoV-2 outbreak, researchers extensively studied pharmacological strategies to decrease the viral load in severe patients. The M-pro protease, which is essential for viral replication, has been identified as a potential therapeutic target. To prevent further spread of the pandemic, scientists are actively searching for more efficient inhibitors against SARS-CoV-2.

BIOENGINEERING-BASEL (2023)

Article Biotechnology & Applied Microbiology

Biosurfactant-producing Aspergillus, Penicillium, and Candida Performed Higher Biodegradation of Diesel Oil than a Non-producing Fungal Strain

A. H. A. Khan, S. Tanveer, A. Kiyani, R. Barros, M. Iqbal, S. Yousaf

Summary: This research identified the potential of biosurfactant-producing fungal strains belonging to Aspergillus, Penicillium, and Candida genera for enhancing the hydrocarbon degradation process. The highest biodegradation was observed in Aspergillus niger FA5, followed by Penicillium chrysogenum FP4, Aspergillus terreus FP6, and Candida sp. FG2. The results indicate that fungi capable of producing biosurfactants and effectively reducing surface tension show significant improvements in the rate of hydrocarbon degradation.

APPLIED BIOCHEMISTRY AND MICROBIOLOGY (2023)

Article Chemistry, Applied

Structural, vibrational, optical, and anticancer properties of Hyphaene thebaica-reduced nano-lanthanum oxide (La2O3)

Hamza Elsayed Ahmad Mohamed, Ali Talha Khalil, Khaoula Hkiri, Muhammad Ayaz, Asad Usman, Abdul Sadiq, Farhat Ullah, Muhammad Arif Khan, Arshad Islam, Muhammad Ovais, Malik Maaza

Summary: Phytoextracts of Hyphaene thebaica were used to synthesize nano-scaled spherical lanthanum oxide nanoparticles (La2O3 NPs) as a bioreducing and chelating agent. XRD, HR-TEM, and infrared spectroscopy confirmed the purity and crystalline nature of the HT-La2O3 NPs. The NPs showed potential antioxidant, anticancer, antiangiogenic, and cytotoxic properties, with highest DPPH scavenging activity and median lethal concentration values on MCF-7 and 3T3 cell lines.

APPLIED ORGANOMETALLIC CHEMISTRY (2023)

Article Chemistry, Medicinal

Chemical and Nutritional Profiling of the Seaweed Dictyota dichotoma and Evaluation of Its Antioxidant, Antimicrobial and Hypoglycemic Potentials

Muhammad Imran, Arshad Iqbal, Syed Lal Badshah, Ayaz Ali Sher, Hammad Ullah, Muhammad Ayaz, Osama F. Mosa, Nada M. Mostafa, Maria Daglia

Summary: Seaweed is known for its beneficial effects on human health, and Dictyota dichotoma extracts contain various bioactive components such as proteins, fats, and carbohydrates. The extracts also contain multiple compounds, including undecane, cetylic acid, hexadecenoic acid, Z-11-, and myristic acid.

MARINE DRUGS (2023)

Article Medicine, Research & Experimental

In-depth in-vitro and in-vivo anti-diabetic evaluations of Fagonia cretica mediated biosynthesized selenium nanoparticles

Haider Ali Khan, Mehreen Ghufran, Sulaiman Shams, Alam Jamal, Muhammad Ayaz, Mehran Ullah, Abbas Khan, Mohammad Imran Khan, Zuhier A. Awan

Summary: Therapeutic moieties derived from medicinal plants and plants-based ecofriendly processes for producing selenium nanoparticles have shown great promise in managing type 2 diabetes mellitus. The current study aimed to assess the anti-diabetic potentials of Fagonia cretica mediated biogenic selenium nanoparticles (FcSeNPs) using in-vitro and in-vivo approaches. FcSeNPs demonstrated dose-dependent inhibition against alpha-amylase and alpha-glucosidase and significant antioxidant activity against DPPH and ABTS radicals. Treatment with FcSeNPs resulted in a considerable decline in blood glucose levels in STZ-induced diabetic mice and improved biochemical parameters related to pancreas, liver, kidney, and lipid profile.

BIOMEDICINE & PHARMACOTHERAPY (2023)

Article Biochemistry & Molecular Biology

Higher cadmium and zinc accumulation in parsley (Petroselinum crispum) roots activates its antioxidants defense system

Ismat Nawaz, Atifa Mehboob, Aqib Hassan Ali Khan, Tatheer Alam Naqvi, Nazneen Bangash, Sadia Aziz, Wajiha Khan, Irum Shahzadi, Rocio Barros, Kifayat Ullah, Mohammad Maroof Shah

Summary: Parsley experiences inhibited growth and induced non-enzymatic antioxidant activity under Cd stress, but decreased activity under Zn stress. Cd uptake and accumulation is higher in roots, suggesting reduced ability to translocate Cd to aboveground parts (leaves).

BIOMETALS (2023)

Review Biotechnology & Applied Microbiology

Nanomedicine as a potential novel therapeutic approach against the dengue virus

Tanzeel Zohra, Faryal Saeed, Aamer Ikram, Tariq Khan, Siyab Alam, Muhammad Adil, Ayesha Gul, Saud Almawash, Muhammad Ayaz

Summary: This review explores the role of nanomedicine-based therapeutic agents against dengue virus and introduces a potential method for better treatment.

NANOMEDICINE (2023)

Article Immunology

2-Hydroxybenzohydrazide as a novel potential candidate against nociception, inflammation, and pyrexia: in vitro, in vivo, and computational approaches

Gowhar Ali, Nazar Ul Islam, Muhammad Qaim, Rahim Ullah, Muhammad Saeed Jan, Khadija Shabbiri, Muhammad Shafique, Muhammad Ayaz

Summary: This study evaluated the efficacy of 2-hydroxybenzohydrazide (HBH) as a drug against pyrexia, inflammation, and nociception, as well as its therapeutic effects on oxidative stress and C-reactive proteins. The findings showed that HBH dose-dependently inhibited pain, inflammation, and pyrexia, and had significant anti-nociceptive, anti-inflammatory, and antipyretic activities involving opioidergic mechanism. Computational studies also revealed HBH's affinity for the COX-I/II target receptors.

INFLAMMOPHARMACOLOGY (2023)

Article Agronomy

Antimalarial and Antileishmanial Flavonoids from Calendula officinalis Flowers

Arwa A. Al-Huqail, Adnan A. Bekhit, Hammad Ullah, Muhammad Ayaz, Nada M. Mostafa

Summary: This study identified compounds in marigold flower extract and evaluated their potential as anti-leishmanial and anti-malarial agents. The results showed that marigold flowers are rich in flavonoids and have antibacterial effects against certain diseases.

AGRONOMY-BASEL (2023)

Article Chemistry, Multidisciplinary

Involvement of the Opioidergic Mechanism in the Analgesic Potential of a Novel Indazolone Derivative: Efficacy in the Management of Pain, Neuropathy, and Inflammation Using In Vivo and In Silico Approaches

Qarib Ullah, Zarshad Ali, Umer Rashid, Gowhar Ali, Nisar Ahmad, Rasool Khan, Sami Ullah, Muhammad Ayaz, H. C. Ananda Murthy

Summary: This study evaluated a novel indazolone derivative for its activity against pain, neuropathy, and inflammation. The results showed that the derivative exhibited significant inhibitory effects on nociception and inflammation, suggesting its potential as a therapeutic agent for the treatment of pyrexia, chemotherapy-induced neuropathic pain, and nociceptive inflammatory pain in the future.

ACS OMEGA (2023)

Article Plant Sciences

Quantitative-HPLC-DAD polyphenols analysis, anxiolytic and cognition enhancing potentials of Sorbaria tomentosa Lindl. Rehder

Mater H. Mahnashi, Muhammad Ayaz, Yahya S. Alqahtani, Bandar A. Alyami, Muhammad Shahid, Omaish Alqahtani, Saeed M. Kabrah, Alam Zeb, Farhat Ullah, Abdul Sadiq

Summary: This study aimed to analyze the phenolic compounds of Sorbaria tomentosa Lindl. Rehder and evaluate its neuroprotective and anxiolytic potentials. The results showed that S. tomentosa contains abundant phenolic compounds with strong antioxidant and acetylcholinesterase inhibitory activities. Moreover, it exhibited improvements in cognition and exploratory behavior, as well as anxiolytic and memory enhancing effects.

JOURNAL OF ETHNOPHARMACOLOGY (2023)

Article Chemistry, Multidisciplinary

Phyto-fabrication of ultrafine nanoscale holmium oxide HT-Ho2O3 NPs and their biomedical potential

Hamze Elsayed Ahmed Mohamed, Ali Talha Khalil, Khaoula Hkiri, Muhammad Ayaz, Assad Usman, Abdul Sadiq, Farhat Ullah, Ishtiaq Hussain, Malik Maaza

Summary: In this study, holmium oxide nanoparticles were synthesized using Hyphaene thebaica extracts as a bioreductant. The nanoparticles exhibited crystalline structure and quasi-spherical morphology with a size range of 6-12 nm. The nanoparticles showed potential antioxidant, anti-angiogenic, and cytotoxic properties, with the ability to inhibit 3T3 cells. The study suggests that biosynthesis using aqueous extracts can be a suitable and eco-friendly method for nanoparticle synthesis.

RSC ADVANCES (2023)

No Data Available