New NO- and H2S-releasing doxorubicins as targeted therapy against chemoresistance in castration-resistant prostate cancer: in vitro and in vivo evaluations

Light-Regulated NO Release as a Novel Strategy To Overcome Doxorubicin Multidrug Resistance

(2017) Konstantin Chegaev et al.   ACS Medicinal Chemistry Letters

Mechanisms of Therapeutic Resistance in Prostate Cancer

(2017) Mary Nakazawa et al.   Current Oncology Reports

Pleiotrophin promotes chemoresistance to doxorubicin in osteosarcoma by upregulating P-glycoprotein

(2017) Dapeng Wu et al.   Oncotarget

Prostate Cancer, Version 2.2014

(2017) James L. Mohler et al.   Journal of the National Comprehensive Cancer Network

Overcoming multidrug resistance by targeting mitochondria with NO-donating doxorubicins

(2016) Elena Gazzano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance

(2016) Konstantin Chegaev et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development and characterization of an in vitro model of colorectal adenocarcinoma with MDR phenotype

(2016) Lorenzo Cinci et al.   Cancer Medicine

Doxorubicin Conjugated to Immunomodulatory Anticancer Lactoferrin Displays Improved Cytotoxicity Overcoming Prostate Cancer Chemo resistance and Inhibits Tumour Development in TRAMP Mice

(2016) Jayanth Suryanarayanan Shankaranarayanan et al.   Scientific Reports

Understanding and overcoming the mechanisms of primary and acquired resistance to abiraterone and enzalutamide in castration resistant prostate cancer

(2015) Consuelo Buttigliero et al.   CANCER TREATMENT REVIEWS

Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting reactive oxygen species-activated extracellular signal-regulated kinase 1/2 in H9c2 cardiac myocytes

(2015) MI-HUA LIU et al.   Molecular Medicine Reports

Strategies to increase nitric oxide signalling in cardiovascular disease

(2015) Jon O. Lundberg et al.   NATURE REVIEWS DRUG DISCOVERY

The Cardioprotective Effects of Hydrogen Sulfide in Heart Diseases: From Molecular Mechanisms to Therapeutic Potential

(2015) Yaqi Shen et al.   Oxidative Medicine and Cellular Longevity

NCI in vitro and in silico anticancer screen, cell cycle pertubation and apoptosis-inducing potential of new acylated, benzylidene and isopropylidene derivatives of andrographolide

(2014) Charng Choon Wong et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Serum Biomarkers for the Detection of Cardiac Toxicity after Chemotherapy and Radiation Therapy in Breast Cancer Patients

(2014) Sibo Tian et al.   Frontiers in Oncology

Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibition of the p38 MAPK pathway in H9c2 cells

(2013) RUNMIN GUO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Cardiovascular toxicity induced by chemotherapy, targeted agents and radiotherapy: ESMO Clinical Practice Guidelines

(2012) G. Curigliano et al.   ANNALS OF ONCOLOGY

Androgen Receptor on the Move: Boarding the Microtubule Expressway to the Nucleus

(2012) M. Thadani-Mulero et al.   CANCER RESEARCH

Mitochondrial-Targeting Nitrooxy-doxorubicin: A New Approach To Overcome Drug Resistance

(2012) Chiara Riganti et al.   MOLECULAR PHARMACEUTICS

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

Dietary inorganic nitrate alleviates doxorubicin cardiotoxicity: Mechanisms and implications

(2012) Lei Xi et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

The P-glycoprotein multidrug transporter

(2011) Frances J. Sharom   Essays in Biochemistry

Dietary Nitrate Supplementation Protects Against Doxorubicin-Induced Cardiomyopathy by Improving Mitochondrial Function

(2011) Shu-Guang Zhu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hydrogen sulfide protects H9c2 cells against doxorubicin-induced cardiotoxicity through inhibition of endoplasmic reticulum stress

(2011) Xiu-Yu Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity

(2011) Konstantin Chegaev et al.   ACS Medicinal Chemistry Letters

Tubulin-Targeting Chemotherapy Impairs Androgen Receptor Activity in Prostate Cancer

(2010) M.-L. Zhu et al.   CANCER RESEARCH

Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction

(2010) A. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors

(2009) Krupa J Patel et al.   BMC CANCER

Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer

(2009) Qianben Wang et al.   CELL

Hydrogen Sulfide Regulates Cardiac Function and Structure in Adriamycin-Induced Cardiomyopathy

(2009) Yu-Wen Su et al.   CIRCULATION JOURNAL

Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion

(2009) William P Harris et al.   Nature clinical practice. Urology

The role of doxorubicin and epirubicin in the treatment of patients with metastatic hormone-refractory prostate cancer

(2008) Roberto Petrioli et al.   CANCER TREATMENT REVIEWS