Inhibiting autophagy overcomes docetaxel resistance in castration-resistant prostate cancer cells

Autophagy-Regulating microRNAs and Cancer

(2017) Devrim Gozuacik et al.   Frontiers in Oncology

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Docetaxel Activity in the Era of Life-prolonging Hormonal Therapies for Metastatic Castration-resistant Prostate Cancer

(2016) Edoardo Francini et al.   EUROPEAN UROLOGY

Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity

(2015) M. Margarida Bernardo et al.   CANCER RESEARCH

Antiandrogens Inhibit ABCB1 Efflux and ATPase Activity and Reverse Docetaxel Resistance in Advanced Prostate Cancer

(2015) Y. Zhu et al.   CLINICAL CANCER RESEARCH

Glucocorticoid receptor antagonism reverts docetaxel resistance in human prostate cancer

(2015) Jan Kroon et al.   ENDOCRINE-RELATED CANCER

Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells

(2015) Ting Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

(2014) Maria Thadani-Mulero et al.   CANCER RESEARCH

Atomistic Autophagy: The Structures of Cellular Self-Digestion

(2014) James H. Hurley et al.   CELL

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

Glycyrrhetinic Acid Triggers a Protective Autophagy by Activation of Extracellular Regulated Protein Kinases in Hepatocellular Carcinoma Cells

(2014) Zheng-Hai Tang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Epithelial-to-Mesenchymal Transition Mediates Docetaxel Resistance and High Risk of Relapse in Prostate Cancer

(2014) M. Marin-Aguilera et al.   MOLECULAR CANCER THERAPEUTICS

Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model

(2014) H G Nguyen et al.   ONCOGENE

Epigallocatechin-3-Gallate Attenuates Impairment of Learning and Memory in Chronic Unpredictable Mild Stress-Treated Rats by Restoring Hippocampal Autophagic Flux

(2014) Hong-Feng Gu et al.   PLoS One

At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy

(2013) Han-Ming Shen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Epithelial-to-Mesenchymal Transition Leads to Docetaxel Resistance in Prostate Cancer and Is Mediated by Reduced Expression of miR-200c and miR-205

(2012) Martin Puhr et al.   AMERICAN JOURNAL OF PATHOLOGY

Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation

(2012) Weiyang He et al.   Autophagy

IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function

(2012) Malene Ambjørn et al.   Autophagy

Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway

(2012) Jose Félix Moruno-Manchón et al.   BIOCHEMICAL JOURNAL

Green tea: An effective synergist with anticancer drugs for tertiary cancer prevention

(2012) Hirota Fujiki et al.   CANCER LETTERS

Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation

(2012) Lin Li et al.   CELLULAR SIGNALLING

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

(2012) Julia Romanov et al.   EMBO JOURNAL

Rapamycin Causes Upregulation of Autophagy and Impairs Islets Function Both In Vitro and In Vivo

(2011) M. Tanemura et al.   AMERICAN JOURNAL OF TRANSPLANTATION

EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages

(2011) Wei Li et al.   BIOCHEMICAL PHARMACOLOGY

Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells

(2011) Guangmin Xi et al.   CANCER LETTERS

Chemotherapy sensitivity recovery of prostate cancer cells by functional inhibition and knock down of multidrug resistance proteins

(2011) Catherine Sánchez et al.   PROSTATE

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

Rapamycin Activates Autophagy and Improves Myelination in Explant Cultures from Neuropathic Mice

(2010) S. Rangaraju et al.   JOURNAL OF NEUROSCIENCE

Endoplasmic Reticulum Stress-Mediated Autophagy/Apoptosis Induced by Capsaicin (8-Methyl-N-vanillyl-6-nonenamide) and Dihydrocapsaicin is Regulated by the Extent of c-Jun NH2-Terminal Kinase/Extracellular Signal-Regulated Kinase Activation in WI38 Lung Epithelial Fibroblast Cells

(2009) S.-H. Oh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells

(2009) Donglei Liu et al.   MEDICAL ONCOLOGY

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy in tumour suppression and promotion

(2009) Andreas Brech et al.   Molecular Oncology

Antioxidative and anti-carcinogenic activities of tea polyphenols

(2008) Chung S. Yang et al.   ARCHIVES OF TOXICOLOGY

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL