Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

Endoplasmic-reticulum stress pathway-associated mechanisms of action of proteasome inhibitors in multiple myeloma

(2016) Masaki Ri   INTERNATIONAL JOURNAL OF HEMATOLOGY

Magic year for multiple myeloma therapeutics: Key takeaways from the ASH 2015 annual meeting

(2016) Kejie Zhang et al.   Oncotarget

Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08)

(2015) C. Driessen et al.   HAEMATOLOGICA

Experimental Evidence Shows Salubrinal, an eIF2α Dephosphorylation Inhibitor, Reduces Xenotoxicant-Induced Cellular Damage

(2015) Masato Matsuoka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08)

(2015) C. Driessen et al.   HAEMATOLOGICA

Looking downstream: the role of cyclic AMP-regulated genes in axonal regeneration

(2015) Mustafa M. Siddiq et al.   Frontiers in Molecular Neuroscience

Effect of cAMP signaling on expression of glucocorticoid receptor, Bim and Bad in glucocorticoid-sensitive and resistant leukemic and multiple myeloma cells

(2015) Hongli Dong et al.   Frontiers in Pharmacology

New insights into the roles of CHOP-induced apoptosis in ER stress

(2014) Yiming Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase

(2013) Tabetha Sundin et al.   EXPERIMENTAL CELL RESEARCH

Disruption of an hTERT–mTOR–RAPTOR protein complex by a phytochemical perillyl alcohol and rapamycin

(2013) Tabetha Sundin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Endoplasmic Reticulum Stress and the Unfolded Protein Response: Targeting the Achilles Heel of Multiple Myeloma

(2013) L. Vincenz et al.   MOLECULAR CANCER THERAPEUTICS

Endoplasmic Reticulum Stress and Type 2 Diabetes

(2012) Sung Hoon Back et al.   Annual Review of Biochemistry

Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

(2012) Axel H. Schönthal   BIOCHEMICAL PHARMACOLOGY

The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells

(2012) Tabetha Sundin et al.   BIOCHIMIE

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress

(2012) Richard Jäger et al.   BIOLOGY OF THE CELL

Pharmacokinetic, Pharmacodynamic and Covariate Analysis of Subcutaneous Versus Intravenous Administration of Bortezomib in Patients with Relapsed Multiple Myeloma

(2012) Philippe Moreau et al.   CLINICAL PHARMACOKINETICS

CHOP is a multifunctional transcription factor in the ER stress response

(2012) H. Nishitoh   JOURNAL OF BIOCHEMISTRY

Perillyl Alcohol for the Treatment of Temozolomide-Resistant Gliomas

(2012) H.-Y. Cho et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of chlorine-induced lung injury by the type 4 phosphodiesterase inhibitor rolipram

(2012) Weiyuan Chang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models

(2011) Thomas C. Chen et al.   CANCER LETTERS

Preclinical Development of Novel Anti-Glioma Drugs Targeting the Endoplasmic Reticulum Stress Response

(2011) Axel H. Schonthal et al.   CURRENT PHARMACEUTICAL DESIGN

ERK and PDE4 cooperate to induce RAF isoform switching in melanoma

(2011) Amélie Marquette et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Signaling cell death from the endoplasmic reticulum stress response

(2010) Gordon C Shore et al.   CURRENT OPINION IN CELL BIOLOGY

The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor

(2010) Diogo G. Garcia et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Chronic Lymphocytic Leukemia and B and T Cells Differ in Their Response to Cyclic Nucleotide Phosphodiesterase Inhibitors

(2009) J. A. Meyers et al.   JOURNAL OF IMMUNOLOGY

Increased Survivin Expression Confers Chemoresistance to Tumor-Associated Endothelial Cells

(2008) Jenilyn J. Virrey et al.   AMERICAN JOURNAL OF PATHOLOGY

Aggravated Endoplasmic Reticulum Stress as a Basis for Enhanced Glioblastoma Cell Killing by Bortezomib in Combination with Celecoxib or Its Non-Coxib Analogue, 2,5-Dimethyl-Celecoxib

(2008) A. Kardosh et al.   CANCER RESEARCH

Targeted Inhibition of Cyclic AMP Phosphodiesterase-4 Promotes Brain Tumor Regression

(2008) P. Goldhoff et al.   CLINICAL CANCER RESEARCH

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY