Surface Functionalization and Targeting Strategies of Liposomes in Solid Tumor Therapy: A Review

Aptamer-functionalized hybrid nanoparticle for the treatment of breast cancer

(2017) David Powell et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Anti-HER2 immunoliposomes for co-delivery of paclitaxel and rapamycin for breast cancer therapy

(2017) Josimar O. Eloy et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Drug delivery to solid tumors: the predictive value of the multicellular tumor spheroid model for nanomedicine screening

(2017) Marie Millard et al.   International Journal of Nanomedicine

Near-infrared light-triggered drug release from a multiple lipid carrier complex using an all-in-one strategy

(2017) Huipeng Li et al.   JOURNAL OF CONTROLLED RELEASE

Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides

(2017) Shama Dissanayake et al.   JOURNAL OF CONTROLLED RELEASE

Redox-sensitive and hyaluronic acid functionalized liposomes for cytoplasmic drug delivery to osteosarcoma in animal models

(2017) Yingying Chi et al.   JOURNAL OF CONTROLLED RELEASE

Construction and evaluation of pH-sensitive immunoliposomes for enhanced delivery of anticancer drug to ErbB2 over-expressing breast cancer cells

(2017) Tianshu Li et al.   Nanomedicine-Nanotechnology Biology and Medicine

Liposomal Formulations in Clinical Use: An Updated Review

(2017) Upendra Bulbake et al.   Pharmaceutics

Pulmonary delivery of triptolide-loaded liposomes decorated with anti-carbonic anhydrase IX antibody for lung cancer therapy

(2017) Congcong Lin et al.   Scientific Reports

Improvement in the drug delivery and anti-tumor efficacy of PEGylated liposomal doxorubicin by targeting RNA aptamers in mice bearing breast tumor model

(2016) Seyedeh Alia Moosavian et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

RGD-TPGS decorated theranostic liposomes for brain targeted delivery

(2016) Sonali et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

RGD(Arg-Gly-Asp) internalized docetaxel-loaded pH sensitive liposomes: Preparation, characterization and antitumor efficacy in vivo and in vitro

(2016) Tiantian Zuo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape

(2016) Claudia Zylberberg et al.   DRUG DELIVERY

Anti-cancer activity of doxorubicin-loaded liposomes co-modified with transferrin and folic acid

(2016) Shravan Kumar Sriraman et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Liposomal drug delivery systems for targeted cancer therapy: is active targeting the best choice?

(2016) Shaghayegh Fathi et al.   Future Medicinal Chemistry

Anti-EphA10 antibody-conjugated pH-sensitive liposomes for specific intracellular delivery of siRNA

(2016) Xinlong Zang et al.   International Journal of Nanomedicine

Dual stimulus of hyperthermia and intracellular redox environment triggered release of siRNA for tumor-specific therapy

(2016) Yanfang Yang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Tumor-specific pH-responsive peptide-modified pH-sensitive liposomes containing doxorubicin for enhancing glioma targeting and anti-tumor activity

(2016) Yang Zhao et al.   JOURNAL OF CONTROLLED RELEASE

Improvement of Peptide-Based Tumor Immunotherapy Using pH-Sensitive Fusogenic Polymer-Modified Liposomes

(2016) Yuta Yoshizaki et al.   MOLECULES

Prostate-specific membrane antigen-targeted liposomes specifically deliver the Zn2+ chelator TPEN inducing oxidative stress in prostate cancer cells

(2016) Christopher H Stuart et al.   Nanomedicine

The next generation cell-penetrating peptide and carbon dot conjugated nano-liposome for transdermal delivery of curcumin

(2016) Santanu Patra et al.   Biomaterials Science

Recent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy

(2016) Ewelina Piktel et al.   JOURNAL OF NANOBIOTECHNOLOGY

Liposomal Drug Delivery: A Versatile Platform for Challenging Clinical Applications

(2016) Asadullah Madni et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Therapeutic efficacy of doxorubicin delivery by a CO2 generating liposomal platform in breast carcinoma

(2015) Hee Dong Han et al.   Acta Biomaterialia

Aptamer-Modified Temperature-Sensitive Liposomal Contrast Agent for Magnetic Resonance Imaging

(2015) Kunchi Zhang et al.   BIOMACROMOLECULES

Human epidermal growth factor receptor-2 antibodies enhance the specificity and anticancer activity of light-sensitive doxorubicin-labeled liposomes

(2015) Qingpo Li et al.   BIOMATERIALS

Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondria targeting and pH-response

(2015) Lei Jiang et al.   BIOMATERIALS

Inhibition of pulmonary cancer progression by epidermal growth factor receptor-targeted transfection with Bcl-2 and survivin siRNAs

(2015) Y K Lee et al.   CANCER GENE THERAPY

Improved therapeutic activity of HER2 Affibody-targeted cisplatin liposomes in HER2-expressing breast tumor models

(2015) Seyedeh Hoda Alavizadeh et al.   Expert Opinion on Drug Delivery

Exploring Different Strategies for Efficient Delivery of Colorectal Cancer Therapy

(2015) Congcong Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An efficient PEGylated liposomal nanocarrier containing cell-penetrating peptide and pH-sensitive hydrazone bond for enhancing tumor-targeted drug delivery

(2015) Ying Xie et al.   International Journal of Nanomedicine

Epidermal growth factor receptor-targeted immunoliposomes for delivery of celecoxib to cancer cells

(2015) Yanuar Dwi Putra Limasale et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Design of Multifunctional Liposomal Nanocarriers for Folate Receptor-Specific Intracellular Drug Delivery

(2015) Min Hyung Kang et al.   MOLECULAR PHARMACEUTICS

Targeting Carbonic Anhydrase IX Activity and Expression

(2015) Brian Mahon et al.   MOLECULES

Stimuli-responsive liposomes for the delivery of nucleic acid therapeutics

(2015) Fatemeh Movahedi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Targeting cancer cells in the tumor microenvironment: opportunities and challenges in combinatorial nanomedicine

(2015) Samuel S. Linton et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Current Approaches for Improving Intratumoral Accumulation and Distribution of Nanomedicines

(2015) Mikhail O Durymanov et al.   Theranostics

Advances and Challenges of Liposome Assisted Drug Delivery

(2015) Lisa Sercombe et al.   Frontiers in Pharmacology

Functionalizing Liposomes with anti-CD44 Aptamer for Selective Targeting of Cancer Cells

(2014) Walhan Alshaer et al.   BIOCONJUGATE CHEMISTRY

Potentiation of pH-sensitive polymer-modified liposomes with cationic lipid inclusion as antigen delivery carriers for cancer immunotherapy

(2014) Yuta Yoshizaki et al.   BIOMATERIALS

The Potential of Liposomes with Carbonic Anhydrase IX to Deliver Anticancer Ingredients to Cancer Cells in Vivo

(2014) Huei Ng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanotechnology-based drug delivery systems for treatment of oral cancer: a review

(2014) Giovana Calixto et al.   International Journal of Nanomedicine

Localized delivery of doxorubicin in vivo from polymer-modified thermosensitive liposomes with MR-guided focused ultrasound-mediated heating

(2014) Terence Ta et al.   JOURNAL OF CONTROLLED RELEASE

Monoclonal antibody-targeted, temperature-sensitive liposomes: In vivo tumor chemotherapeutics in combination with mild hyperthermia

(2014) Zahraa S. Al-Ahmady et al.   JOURNAL OF CONTROLLED RELEASE

RNA aptamer-conjugated liposome as an efficient anticancer drug delivery vehicle targeting cancer cells in vivo

(2014) Si Eun Baek et al.   JOURNAL OF CONTROLLED RELEASE

Synergistic Dual-Ligand Doxorubicin Liposomes Improve Targeting and Therapeutic Efficacy of Brain Glioma in Animals

(2014) Taili Zong et al.   MOLECULAR PHARMACEUTICS

Carbonic anhydrase IX-directed immunoliposomes for targeted drug delivery to human lung cancer cells in vitro

(2014) Zhijun Yang et al.   Drug Design Development and Therapy

Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology

(2013) Nicolas Bertrand et al.   ADVANCED DRUG DELIVERY REVIEWS

The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors

(2013) Hiroto Hatakeyama et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Nano-engineering of 5-fluorouracil-loaded magnetoliposomes for combined hyperthermia and chemotherapy against colon cancer

(2013) Beatriz Clares et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Current trends in the use of liposomes for tumor targeting

(2013) Pranali P Deshpande et al.   Nanomedicine

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Iron Deprivation in Cancer––Potential Therapeutic Implications

(2013) Jessica Heath et al.   Nutrients

Liposome: classification, preparation, and applications

(2013) Abolfazl Akbarzadeh et al.   Nanoscale Research Letters

Bioavailability of Polyphenol Liposomes: A Challenge Ahead

(2013) Nathalie Mignet et al.   Pharmaceutics

Challenges in Development of Targeted Liposomal Therapeutics

(2012) Rupa R. Sawant et al.   AAPS Journal

Nanoparticles in drug delivery: Past, present and future

(2012) P. Couvreur   ADVANCED DRUG DELIVERY REVIEWS

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Novel Multifunctional Theranostic Liposome Drug Delivery System: Construction, Characterization, and Multimodality MR, Near-Infrared Fluorescent, and Nuclear Imaging

(2012) Shihong Li et al.   BIOCONJUGATE CHEMISTRY

Increased apoptosis in cancer cells in vitro and in vivo by ceramides in transferrin-modified liposomes

(2012) Alexander Koshkaryev et al.   CANCER BIOLOGY & THERAPY

A critical review of lipid-based nanoparticles for taxane delivery

(2012) Lan Feng et al.   CANCER LETTERS

Materials characterization of the low temperature sensitive liposome (LTSL): effects of the lipid composition (lysolipid and DSPE–PEG2000) on the thermal transition and release of doxorubicin

(2012) David Needham et al.   FARADAY DISCUSSIONS

Stimulus-responsive nanopreparations for tumor targeting

(2012) Lin Zhu et al.   Integrative Biology

Cyclic RGD peptide-modified liposomal drug delivery system: enhanced cellular uptake in vitro and improved pharmacokinetics in rats

(2012) Zhongya Chen et al.   International Journal of Nanomedicine

Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo

(2012) Swati Biswas et al.   JOURNAL OF CONTROLLED RELEASE

Improvement of drug safety by the use of lipid-based nanocarriers

(2012) Sok Bee Lim et al.   JOURNAL OF CONTROLLED RELEASE

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Study of quercetin-loaded liposomes as potential drug carriers:in vitroevaluation of human complement activation

(2012) Ana Paula Landi-Librandi et al.   JOURNAL OF LIPOSOME RESEARCH

Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells

(2012) Meihua Yu et al.   Nanoscale

Digestion and depletion of abundant proteins improves proteomic coverage

(2012) Bryan R Fonslow et al.   NATURE METHODS

Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities

(2012) Z. Cheng et al.   SCIENCE

Cell-penetrating peptides: breaking through to the other side

(2012) Erez Koren et al.   TRENDS IN MOLECULAR MEDICINE

pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates

(2011) Arnaud E. Felber et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeting Tumor-Associated Endothelial Cells: Anti-VEGFR2 Immunoliposomes Mediate Tumor Vessel Disruption and Inhibit Tumor Growth

(2011) A. Wicki et al.   CLINICAL CANCER RESEARCH

In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain

(2011) S. Rahima Benhabbour et al.   JOURNAL OF CONTROLLED RELEASE

Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting

(2011) Swati Biswas et al.   JOURNAL OF DRUG TARGETING

Cetuximab-labeled liposomes containing near-infrared probe for in vivo imaging

(2011) Emma Portnoy et al.   Nanomedicine-Nanotechnology Biology and Medicine

Gold nanoparticles: opportunities and challenges in nanomedicine

(2010) Rochelle Arvizo et al.   Expert Opinion on Drug Delivery

From “Banghasomes” to liposomes: A memoir of Alec Bangham, 1921–2010

(2010) David W. Deamer   FASEB JOURNAL

Antibody derivatization and conjugation strategies: Application in preparation of stealth immunoliposome to target chemotherapeutics to tumor

(2010) Arehalli S. Manjappa et al.   JOURNAL OF CONTROLLED RELEASE

A Transferrin Receptor-Targeted Liposomal Formulation for Docetaxel

(2010) Guangxi Zhai et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Integrin-targeted paclitaxel nanoliposomes for tumor therapy

(2010) Shuyan Meng et al.   MEDICAL ONCOLOGY

Drug Targeting Strategies in Cancer Treatment: An Overview

(2010) J. L. Arias   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Roles of Fibroblast Growth Factor Receptors in Carcinogenesis

(2010) E. M. Haugsten et al.   MOLECULAR CANCER RESEARCH

The molecular basis of the blood brain barrier differentiation and maintenance. Is it still a mystery?

(2010) Roberta Paolinelli et al.   PHARMACOLOGICAL RESEARCH

Effects of nanomaterial physicochemical properties on in vivo toxicity

(2009) Kristin L. Aillon et al.   ADVANCED DRUG DELIVERY REVIEWS

Reversible Cell-Specific Drug Delivery with Aptamer-Functionalized Liposomes

(2009) Zehui Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Five-Year Efficacy and Safety Analysis of the Adenoma Prevention with Celecoxib Trial

(2009) M. M. Bertagnolli et al.   Cancer Prevention Research

A liposome-based nanostructure for aptamer directed delivery

(2009) Huaizhi Kang et al.   CHEMICAL COMMUNICATIONS

Targeted delivery of doxorubicin using stealth liposomes modified with transferrin

(2009) XueMing Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Targeted temperature sensitive magnetic liposomes for thermo-chemotherapy

(2009) Pallab Pradhan et al.   JOURNAL OF CONTROLLED RELEASE

Effect of Surface Properties on Nanoparticle–Cell Interactions

(2009) Ayush Verma et al.   Small

VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo

(2008) Sara Gosk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Imaging of cationic multifunctional liposome-mediated delivery of COX-2 siRNA

(2008) M Mikhaylova et al.   CANCER GENE THERAPY

Hydrogels in drug delivery: Progress and challenges

(2008) Todd R. Hoare et al.   POLYMER

Functionalized-Quantum-Dot-Liposome Hybrids as Multimodal Nanoparticles for Cancer

(2008) Wafa' T. Al-Jamal et al.   Small

Discovery and Development of Folic-Acid-Based Receptor Targeting for Imaging and Therapy of Cancer and Inflammatory Diseases

(2007) Philip S. Low et al.   ACCOUNTS OF CHEMICAL RESEARCH