Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 3, Pages 677
Publisher
MDPI AG
Online
2018-03-01
DOI
10.3390/ijms19030677
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Therapeutic monoclonal antibody N-glycosylation – Structure, function and therapeutic potential
- (2018) Florian Cymer et al. BIOLOGICALS
- Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease
- (2018) Jose D. Pagan et al. CELL
- Targeting pattern-recognition receptors to discover new small molecule immune modulators
- (2018) Gengzheng Zhu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Immunopathogenesis of Rheumatoid Arthritis
- (2017) Gary S. Firestein et al. IMMUNITY
- STA-21, a STAT-3 inhibitor, attenuates the development and progression of inflammation in collagen antibody-induced arthritis
- (2017) Sheikh Fayaz Ahmad et al. IMMUNOBIOLOGY
- PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells
- (2017) Jong-Sung Park et al. JOURNAL OF CONTROLLED RELEASE
- Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein–Associated Serine Protease 2
- (2017) Nirmal K. Banda et al. JOURNAL OF IMMUNOLOGY
- Pathogenetic insights from the treatment of rheumatoid arthritis
- (2017) Iain B McInnes et al. LANCET
- Synovial tissue research: a state-of-the-art review
- (2017) Carl Orr et al. Nature Reviews Rheumatology
- IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation
- (2017) Stanley C. Jordan et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Immunoregulatory Roles of Antibody Glycosylation
- (2017) Madeleine F. Jennewein et al. TRENDS IN IMMUNOLOGY
- Mechanisms of Autoantibody-Induced Pathology
- (2017) Ralf J. Ludwig et al. Frontiers in Immunology
- Autoantibody pain
- (2016) Andreas Goebel AUTOIMMUNITY REVIEWS
- Plasmapheresis therapy in combination with TNF-α inhibitor and DMARDs: A multitarget method for the treatment of rheumatoid arthritis
- (2016) Yongjing Cheng et al. Modern Rheumatology
- Mechanisms leading from systemic autoimmunity to joint-specific disease in rheumatoid arthritis
- (2016) Anca I. Catrina et al. Nature Reviews Rheumatology
- Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis
- (2016) Yuhsuke Ohmi et al. Nature Communications
- Novel synthetic (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol inhibits arthritis by targeting signal transducer and activator of transcription 3
- (2016) Dong Ju Son et al. Scientific Reports
- Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism
- (2015) Gustaf Wigerblad et al. ANNALS OF THE RHEUMATIC DISEASES
- Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
- (2015) Akilan Krishnamurthy et al. ANNALS OF THE RHEUMATIC DISEASES
- Advances in Antibody Design
- (2015) Kathryn E. Tiller et al. Annual Review of Biomedical Engineering
- A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA
- (2015) Gaurav Mehta et al. JOURNAL OF IMMUNOLOGY
- The Bacterial Enzyme IdeS Cleaves the IgG-Type of B Cell Receptor (BCR), Abolishes BCR-Mediated Cell Signaling, and Inhibits Memory B Cell Activation
- (2015) Sofia Järnum et al. JOURNAL OF IMMUNOLOGY
- Cytokines in rheumatoid arthritis — shaping the immunological landscape
- (2015) Iain B. McInnes et al. Nature Reviews Rheumatology
- Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis
- (2015) Kim L.L. Habets et al. ARTHRITIS RESEARCH & THERAPY
- Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss
- (2015) Ulrike Harre et al. Nature Communications
- Epitope-specific antibody response is controlled by immunoglobulin VHpolymorphisms
- (2014) Bruno Raposo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- In vitro and in vivo modifications of recombinant and human IgG antibodies
- (2014) Hongcheng Liu et al. mAbs
- Autoantibodies to Posttranslational Modifications in Rheumatoid Arthritis
- (2014) Agata N. Burska et al. MEDIATORS OF INFLAMMATION
- The role of collagen antibodies in mediating arthritis
- (2014) Merrill J. Rowley et al. Modern Rheumatology
- Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis
- (2014) Nilesh M. Agalave et al. PAIN
- EndoS Reduces the Pathogenicity of Anti-mCOL7 IgG through Reduced Binding of Immune Complexes to Neutrophils
- (2014) Xinhua Yu et al. PLoS One
- Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice
- (2014) Ingrid Lindh et al. ARTHRITIS RESEARCH & THERAPY
- Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies
- (2013) Arnd Kleyer et al. ANNALS OF THE RHEUMATIC DISEASES
- Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis
- (2013) Yoann Rombouts et al. ANNALS OF THE RHEUMATIC DISEASES
- Essential Role of Surface-Bound Complement Factor H in Controlling Immune Complex-Induced Arthritis
- (2013) N. K. Banda et al. JOURNAL OF IMMUNOLOGY
- Prevention of Arthritis by Locally Synthesized Recombinant Antibody Neutralizing Complement Component C5
- (2013) Paolo Durigutto et al. PLoS One
- Inflammatory monocytes and Fc receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice
- (2013) M. Seeling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signaling
- (2013) F. Wermeling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species
- (2012) Tiina Kelkka et al. AMERICAN JOURNAL OF PATHOLOGY
- Genetic control of antibody production during collagen-induced arthritis development in heterogeneous stock mice
- (2012) Michael Förster et al. ARTHRITIS AND RHEUMATISM
- Treatment of experimental arthritis by targeting synovial endothelium with a neutralizing recombinant antibody to C5
- (2012) Paolo Macor et al. ARTHRITIS AND RHEUMATISM
- Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency
- (2012) Duygu B. Bas et al. ARTHRITIS AND RHEUMATISM
- Type II collagen-specific antibodies induce cartilage damage in mice independent of inflammation
- (2012) Allyson M. Croxford et al. ARTHRITIS AND RHEUMATISM
- Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen
- (2012) Misa Hirose et al. JOURNAL OF AUTOIMMUNITY
- Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin
- (2012) Ulrike Harre et al. JOURNAL OF CLINICAL INVESTIGATION
- IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis
- (2012) Mahdia Benkhoucha et al. Journal of Neuroinflammation
- Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
- (2012) Soumya Raychaudhuri et al. NATURE GENETICS
- Monoclonal anti-citrullinated protein antibodies selected on citrullinated fibrinogen have distinct targets with different cross-reactivity patterns
- (2012) L. A. van de Stadt et al. RHEUMATOLOGY
- Cartilage oligomeric matrix protein specific antibodies are pathogenic
- (2012) Hui Geng et al. ARTHRITIS RESEARCH & THERAPY
- A dominant suppressive MHC class II haplotype interacting with autosomal genes controls autoantibody production and chronicity of arthritis
- (2011) K. S. Nandakumar et al. ANNALS OF THE RHEUMATIC DISEASES
- Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis
- (2011) P. Suwannalai et al. ARTHRITIS AND RHEUMATISM
- Chemical changes demonstrated in cartilage by synchrotron infrared microspectroscopy in an antibody-induced murine model of rheumatoid arthritis
- (2011) Allyson M. Croxford et al. JOURNAL OF BIOMEDICAL OPTICS
- Pathogenic Autoreactive B Cells Are Not Negatively Selected toward Matrix Protein Collagen II
- (2011) D. Cao et al. JOURNAL OF IMMUNOLOGY
- Role of C3a Receptors, C5a Receptors, and Complement Protein C6 Deficiency in Collagen Antibody-Induced Arthritis in Mice
- (2011) N. K. Banda et al. JOURNAL OF IMMUNOLOGY
- Inhibiting the C5–C5a receptor axis
- (2011) Trent M. Woodruff et al. MOLECULAR IMMUNOLOGY
- Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway
- (2011) Robert M. Anthony et al. NATURE
- The Pathogenesis of Rheumatoid Arthritis
- (2011) Iain B. McInnes et al. NEW ENGLAND JOURNAL OF MEDICINE
- Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose
- (2011) C. Ferrara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells
- (2010) M. Hultqvist et al. ANNALS OF THE RHEUMATIC DISEASES
- Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis
- (2010) D. van der Woude et al. ANNALS OF THE RHEUMATIC DISEASES
- Specific antibody protection of the extracellular cartilage matrix against collagen antibody-induced damage
- (2010) Allyson M. Croxford et al. ARTHRITIS AND RHEUMATISM
- Neutrophils in a mouse model of autoantibody-mediated arthritis: Critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function−associated antigen 1
- (2010) Paul A. Monach et al. ARTHRITIS AND RHEUMATISM
- 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative
- (2010) Daniel Aletaha et al. ARTHRITIS AND RHEUMATISM
- Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity
- (2010) E. Mossner et al. BLOOD
- The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis
- (2010) M. Allhorn et al. BLOOD
- A Novel Role for the IgG Fc Glycan: The Anti-inflammatory Activity of Sialylated IgG Fcs
- (2010) Robert M. Anthony et al. JOURNAL OF CLINICAL IMMUNOLOGY
- IgG Glycan Hydrolysis Attenuates ANCA-Mediated Glomerulonephritis
- (2010) M. M. van Timmeren et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes
- (2010) R. Yang et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis
- (2010) Christina A. Christianson et al. PAIN
- A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis
- (2010) Kutty Selva Nandakumar et al. PLoS One
- Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways
- (2009) L. A. Trouw et al. ARTHRITIS AND RHEUMATISM
- Pathogenic antibody recognition of cartilage
- (2009) Kutty Selva Nandakumar CELL AND TISSUE RESEARCH
- Antibodies to citrullinated proteins: molecular interactions and arthritogenicity
- (2009) Hüseyin Uysal et al. IMMUNOLOGICAL REVIEWS
- Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis
- (2009) Hüseyin Uysal et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Collagen antibody-induced arthritis in mice: Development of a new arthritogenic 5-clone cocktail of monoclonal anti-type II collagen antibodies
- (2009) Pilaiwanwadee Hutamekalin et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Targeted Inhibition of the Complement Alternative Pathway with Complement Receptor 2 and Factor H Attenuates Collagen Antibody-Induced Arthritis in Mice
- (2009) N. K. Banda et al. JOURNAL OF IMMUNOLOGY
- IL-17-producing T cells can augment autoantibody-induced arthritis
- (2009) J. P. Jacobs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse models of autoimmune disorders
- (2008) M Hultqvist et al. ANNALS OF THE RHEUMATIC DISEASES
- Anti-Inflammatory Actions of Intravenous Immunoglobulin
- (2008) Falk Nimmerjahn et al. Annual Review of Immunology
- Immunity to Citrullinated Proteins in Rheumatoid Arthritis
- (2008) Lars Klareskog et al. Annual Review of Immunology
- Cartilage oligomeric matrix protein induction of chronic arthritis in mice
- (2008) Stefan Carlsen et al. ARTHRITIS AND RHEUMATISM
- In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner
- (2008) H. Albert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions
- (2008) M. Collin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a receptor required for the anti-inflammatory activity of IVIG
- (2008) R. M. Anthony et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc
- (2008) R. M. Anthony et al. SCIENCE
- Therapeutic cleavage of IgG: new avenues for treating inflammation
- (2008) Kutty Selva Nandakumar et al. TRENDS IN IMMUNOLOGY
- Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis
- (2008) Keiichi Iwanami et al. ARTHRITIS RESEARCH & THERAPY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started