Organ-Specific MicroRNAs (MIR122, 137, and 206) Contribute to Tissue Characteristics and Carcinogenesis by Regulating Pyruvate Kinase M1/2 (PKM) Expression

Pyruvate kinase M2 fuels multiple aspects of cancer cells: from cellular metabolism, transcriptional regulation to extracellular signaling

(2018) Ming-Chuan Hsu et al.   Molecular Cancer

Oncogene RNA helicase DDX6 promotes the process of c-Myc expression in gastric cancer cells

(2018) Kohei Taniguchi et al.   MOLECULAR CARCINOGENESIS

A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells

(2017) Tomoaki Takai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Minimal Standards for Reporting microRNA:Target Interactions

(2017) Klara Piletič et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

MicroRNAs: Important Regulators of Induced Pluripotent Stem Cell Generation and Differentiation

(2017) Zhao-Lin Zeng et al.   Stem Cell Reviews and Reports

Cancer-Specific Energy Metabolism in Rhabdomyosarcoma Cells Is Regulated by MicroRNA

(2017) Nobuhiko Sugito et al.   Nucleic Acid Therapeutics

PKM2 in carcinogenesis and oncotherapy

(2017) Xia He et al.   Oncotarget

MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells

(2017) Koichiro Minami et al.   Oncotarget

MicroRNAs: Important Regulators of Induced Pluripotent Stem Cell Generation and Differentiation

(2017) Zhao-Lin Zeng et al.   Stem Cell Reviews and Reports

MiR-133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle-splicer polypyrimidine tract-binding protein 1

(2016) Taro Sugiyama et al.   CANCER SCIENCE

PKM2, cancer metabolism, and the road ahead

(2016) Talya L Dayton et al.   EMBO REPORTS

PTBP1-associated microRNA-1 and -133b suppress the Warburg effect in colorectal tumors

(2016) Kohei Taniguchi et al.   Oncotarget

MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer

(2015) Kohei Taniguchi et al.   CANCER LETTERS

Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

(2015) Miranda Y. Fong et al.   NATURE CELL BIOLOGY

miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants

(2015) T. Desvignes et al.   TRENDS IN GENETICS

Intravesical administration of exogenous microRNA-145 as a therapy for mouse orthotopic human bladder cancer xenograft

(2015) Teruo Inamoto et al.   Oncotarget

Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms

(2015) Kohei Taniguchi et al.   Scientific Reports

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

(2015) Katharina Bluemlein et al.   Oncotarget

Involvement of polypyrimidine tract-binding protein (PTBP1) in maintaining breast cancer cell growth and malignant properties

(2014) X He et al.   Oncogenesis

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

(2012) Wei-Chih Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect

(2012) YAN SUN et al.   ONCOLOGY REPORTS

Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons

(2011) Zhenxun Wang et al.   Journal of Molecular Cell Biology

MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas

(2010) E Missiaglia et al.   BRITISH JOURNAL OF CANCER

Role of anti-oncomirs miR-143 and -145 in human colorectal tumors

(2010) Y Akao et al.   CANCER GENE THERAPY

Turning on a Fuel Switch of Cancer: hnRNP Proteins Regulate Alternative Splicing of Pyruvate Kinase mRNA

(2010) M. Chen et al.   CANCER RESEARCH

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

(2010) C. V. Clower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

(2009) Charles J. David et al.   NATURE

Decreased Expression of MicroRNA-143 and -145 in Human Gastric Cancers

(2009) Takeshi Takagi et al.   ONCOLOGY

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine