The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Renal and Liver Disease in Western Diet Induced Obesity Mice

Nonalcoholic Fatty Liver Disease and Metabolic Syndrome

(2018) Donghee Kim et al.   Clinics in Liver Disease

Antidiabetic and antiobesity effects of SGLT2 inhibitor ipragliflozin in type 2 diabetic mice fed sugar solution

(2018) Atsuo Tahara et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Characterization and comparison of SGLT2 inhibitors: Part 3. Effects on diabetic complications in type 2 diabetic mice

(2017) Atsuo Tahara et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy

(2017) Xiaoxin X. Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Factors predicting non-alcoholic steatohepatitis (NASH) and advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD)

(2017) Abbas Ali Tasneem et al.   TROPICAL DOCTOR

Chronic kidney disease

(2017) Paola Romagnani et al.   Nature Reviews Disease Primers

Non-Alcoholic Fatty Liver Disease: The Emerging Burden in Cardiometabolic and Renal Diseases

(2017) Eugene Han et al.   Diabetes & Metabolism Journal

Serelaxin improves cardiac and renal function in DOCA-salt hypertensive rats

(2017) Dong Wang et al.   Scientific Reports

Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice

(2016) Atsushi Obata et al.   ENDOCRINOLOGY

Label-free fluorescence lifetime and second harmonic generation imaging microscopy improves quantification of experimental renal fibrosis

(2016) Suman Ranjit et al.   KIDNEY INTERNATIONAL

The SGLT-2 Inhibitor Dapagliflozin Has a Therapeutic Effect on Atherosclerosis in Diabetic ApoE−/−Mice

(2016) Weiling Leng et al.   MEDIATORS OF INFLAMMATION

Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis

(2016) Vivette D. D'Agati et al.   Nature Reviews Nephrology

The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice

(2016) Yasushi Honda et al.   PLoS One

Sodium–glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy

(2015) Marko Škrtić et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Insulin stimulates SGLT2-mediated tubular glucose absorption via oxidative stress generation

(2015) Nobutaka Nakamura et al.   Diabetology & Metabolic Syndrome

Sodium Glucose Co-transporter 2 (SGLT2) Inhibitors: New among Antidiabetic Drugs

(2014) L. H. Opie   CARDIOVASCULAR DRUGS AND THERAPY

Diabetic Kidney Disease: A Report From an ADA Consensus Conference

(2014) Katherine R. Tuttle et al.   DIABETES CARE

Long-Term Treatment with the Sodium Glucose Cotransporter 2 Inhibitor, Dapagliflozin, Ameliorates Glucose Homeostasis and Diabetic Nephropathy in db/db Mice

(2014) Naoto Terami et al.   PLoS One

Combating the dual burden: therapeutic targeting of common pathways in obesity and type 2 diabetes

(2014) André J Scheen et al.   Lancet Diabetes & Endocrinology

Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes

(2013) H. J. Lambers Heerspink et al.   DIABETES OBESITY & METABOLISM

Diabetes and Nonalcoholic Fatty Liver Disease: A Pathogenic Duo

(2013) K. H. Williams et al.   ENDOCRINE REVIEWS

Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy

(2013) Michal Herman-Edelstein et al.   JOURNAL OF LIPID RESEARCH

SGLT2 Inhibition: A Novel Prospective Strategy in Treatment of Diabetes Mellitus

(2013) Aaishwarya B. Deshmukh et al.   RENAL FAILURE

Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

(2011) V. Gorboulev et al.   DIABETES

Obesity and Type 2 Diabetes: What Can Be Unified and What Needs to Be Individualized?

(2011) Robert H. Eckel et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Renal lipid metabolism and lipotoxicity

(2010) Ion Alexandru Bobulescu   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice

(2010) Ryan S. Lim et al.   JOURNAL OF LIPID RESEARCH

SGLT2 Mediates Glucose Reabsorption in the Early Proximal Tubule

(2010) V. Vallon et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SGLT2 inhibition — a novel strategy for diabetes treatment

(2010) Edward C. Chao et al.   NATURE REVIEWS DRUG DISCOVERY

Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications

(2009) J. E. Gerich   DIABETIC MEDICINE

Obesity-Associated Liver Disease

(2008) Giulio Marchesini et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM