The art of targeting gut microbiota for tackling human obesity

A Canadian Working Group Report on Fecal Microbial Therapy: Microbial Ecosystems Therapeutics

(2016) Emma Allen-Vercoe et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

Inulin-type fructans modulate intestinal Bifidobacterium species populations and decrease fecal short-chain fatty acids in obese women

(2015) Nuria Salazar et al.   CLINICAL NUTRITION

Gut microbiota and obesity: Involvement of the adipose tissue

(2015) Sonia Guida et al.   Journal of Functional Foods

Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms

(2014) Joe Alcock et al.   BIOESSAYS

Assessing non-digestible compounds in apple cultivars and their potential as modulators of obese faecal microbiota in vitro

(2014) Luis Condezo-Hoyos et al.   FOOD CHEMISTRY

Role of the Microbiome in Energy Regulation and Metabolism

(2014) Max Nieuwdorp et al.   GASTROENTEROLOGY

Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men

(2014) Anne Salonen et al.   ISME Journal

Diet Effects in Gut Microbiome and Obesity

(2014) Jia Chen et al.   JOURNAL OF FOOD SCIENCE

Microbiota, Antibiotics, and Obesity

(2014) Tine Jess   NEW ENGLAND JOURNAL OF MEDICINE

Gut Microbiota Signatures Predict Host and Microbiota Responses to Dietary Interventions in Obese Individuals

(2014) Katri Korpela et al.   PLoS One

In Vitro Characterization of the Impact of Different Substrates on Metabolite Production, Energy Extraction and Composition of Gut Microbiota from Lean and Obese Subjects

(2014) Marisol Aguirre et al.   PLoS One

Identifying Gut Microbe-Host Phenotype Relationships Using Combinatorial Communities in Gnotobiotic Mice

(2014) J. J. Faith et al.   Science Translational Medicine

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Modulation of the Gut Microbiota by Nutrients with Prebiotic and Probiotic Properties

(2014) Céline Druart et al.   Advances in Nutrition

Impact of the gut microbiota on the development of obesity and type 2 diabetes mellitus

(2014) Isabel Moreno-Indias et al.   Frontiers in Microbiology

Association of Antibiotics in Infancy With Early Childhood Obesity

(2014) L. Charles Bailey et al.   JAMA Pediatrics

Replenishing our defensive microbes

(2013) Luke K. Ursell et al.   BIOESSAYS

Therapeutic faecal microbiota transplantation

(2013) Thomas J. Borody et al.   CURRENT OPINION IN GASTROENTEROLOGY

Therapeutic Potential of Fecal Microbiota Transplantation

(2013) Loek P. Smits et al.   GASTROENTEROLOGY

Role of the gut microbiota in human nutrition and metabolism

(2013) Balakrishnan S Ramakrishna   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Impact of Dietary Fiber Fermentation from Cereal Grains on Metabolite Production by the Fecal Microbiota from Normal Weight and Obese Individuals

(2013) Junyi Yang et al.   JOURNAL OF MEDICINAL FOOD

Related actions of probiotics and antibiotics on gut microbiota and weight modification

(2013) Emmanouil Angelakis et al.   LANCET INFECTIOUS DISEASES

The gut microbiota and obesity: from correlation to causality

(2013) Liping Zhao   NATURE REVIEWS MICROBIOLOGY

Anti-Obesity Effect of Lactobacillus gasseri BNR17 in High-Sucrose Diet-Induced Obese Mice

(2013) Ji-Hee Kang et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inter-individual differences in response to dietary intervention: integrating omics platforms towards personalised dietary recommendations

(2013) Johanna W. Lampe et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Interactions between gut microbiota, food and the obese host

(2013) Teresa Requena et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome

(2013) Nathan P. McNulty et al.   PLOS BIOLOGY

Stool substitute transplant therapy for the eradication of Clostridium difficile infection: ‘RePOOPulating’ the gut

(2013) Elaine O Petrof et al.   Microbiome

High-Throughput Sequencing Reveals the Incomplete, Short-Term Recovery of Infant Gut Microbiota following Parenteral Antibiotic Treatment with Ampicillin and Gentamicin

(2012) Fiona Fouhy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of Lactobacillus acidophilus NCDC 13 supplementation on the progression of obesity in diet-induced obese mice

(2012) Tulika Arora et al.   BRITISH JOURNAL OF NUTRITION

The influence of probiotic supplementation on gut permeability in patients with metabolic syndrome: an open label, randomized pilot study

(2012) B Leber et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Fecal Microbiota Transplantation: Are We Opening a Can of Worms?

(2012) Wael El–Matary et al.   GASTROENTEROLOGY

Identifying genomic and metabolic features that can underlie early successional and opportunistic lifestyles of human gut symbionts

(2012) C. Lozupone et al.   GENOME RESEARCH

Gut microbiota disturbance during antibiotic therapy: a multi-omic approach

(2012) Ana Elena Pérez-Cobas et al.   GUT

Colonoscopic versus nasogastric fecal transplantation for the treatment of Clostridium difficile infection: a review and pooled analysis

(2012) R. Postigo et al.   INFECTION

The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome ‘at-risk’ population

(2012) F Fava et al.   INTERNATIONAL JOURNAL OF OBESITY

FAO/WHO Guidelines on Probiotics

(2012) Lorenzo Morelli et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Short communication: Effect of supplementation with Lactobacillus casei Shirota on insulin sensitivity, β-cell function, and markers of endothelial function and inflammation in subjects with metabolic syndrome—A pilot study

(2012) N.J. Tripolt et al.   JOURNAL OF DAIRY SCIENCE

Antibiotics in early life alter the murine colonic microbiome and adiposity

(2012) Ilseung Cho et al.   NATURE

Microbial ecosystems therapeutics: a new paradigm in medicine?

(2012) E.O. Petrof et al.   Beneficial Microbes

Microbial Co-occurrence Relationships in the Human Microbiome

(2012) Karoline Faust et al.   PLoS Computational Biology

Bifidobacterium adolescentis supplementation ameliorates visceral fat accumulation and insulin sensitivity in an experimental model of the metabolic syndrome

(2011) Jinjin Chen et al.   BRITISH JOURNAL OF NUTRITION

Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR:LA-cp rats

(2011) Jill A. Parnell et al.   BRITISH JOURNAL OF NUTRITION

Systematic Review of Intestinal Microbiota Transplantation (Fecal Bacteriotherapy) for Recurrent Clostridium difficile Infection

(2011) Ethan Gough et al.   CLINICAL INFECTIOUS DISEASES

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

(2011) Amandine Everard et al.   DIABETES

Bifidobacterium longum supplementation improved high-fat-fed-induced metabolic syndrome and promoted intestinal Reg I gene expression

(2011) Jin Jin Chen et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to ExacerbatedCitrobacter rodentium-Induced Colitis

(2011) M. Wlodarska et al.   INFECTION AND IMMUNITY

Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii

(2011) M Million et al.   INTERNATIONAL JOURNAL OF OBESITY

Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats

(2011) Hyang An et al.   Lipids in Health and Disease

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

(2011) I. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Manipulation of the gut microbiota in C57BL/6 mice changes glucose tolerance without affecting weight development and gut mucosal immunity

(2011) Gunilla Veslemøy Bech-Nielsen et al.   RESEARCH IN VETERINARY SCIENCE

Predicting a Human Gut Microbiota's Response to Diet in Gnotobiotic Mice

(2011) J. J. Faith et al.   SCIENCE

Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans

(2011) B. D. Muegge et al.   SCIENCE

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Faecal microbiota in breast-fed infants after antibiotic therapy

(2010) F Savino et al.   ACTA PAEDIATRICA

Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation

(2010) Claire Barbier de La Serre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Success of Self-Administered Home Fecal Transplantation for Chronic Clostridium difficile Infection

(2010) Michael S. Silverman et al.   Clinical Gastroenterology and Hepatology

Impact of dietary counselling and probiotic intervention on maternal anthropometric measurements during and after pregnancy: A randomized placebo-controlled trial

(2010) Johanna Ilmonen et al.   CLINICAL NUTRITION

Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial

(2010) Y Kadooka et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

The impact of perinatal probiotic intervention on the development of overweight and obesity: follow-up study from birth to 10 years

(2010) R Luoto et al.   INTERNATIONAL JOURNAL OF OBESITY

Creating and characterizing communities of human gut microbes in gnotobiotic mice

(2010) Jeremiah J Faith et al.   ISME Journal

Functional Genomics of Probiotic Lactobacilli

(2010) Todd R. Klaenhammer et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Effects of Lactobacillus gasseri BNR17 on body weight and adipose tissue mass in diet-induced overweight rats

(2010) Ji-Hee Kang et al.   JOURNAL OF MICROBIOLOGY

One size may not fit all: Pondering antibiotic dosing in obesity

(2010) Hanah N. Polotsky et al.   MATURITAS

Long-term impacts of antibiotic exposure on the human intestinal microbiota

(2010) C. Jernberg et al.   MICROBIOLOGY-SGM

The endocannabinoid system links gut microbiota to adipogenesis

(2010) Giulio G Muccioli et al.   Molecular Systems Biology

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Vancomycin Treatment of Infective Endocarditis Is Linked with Recently Acquired Obesity

(2010) Franck Thuny et al.   PLoS One

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

(2010) L. Dethlefsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal

(2009) Patrice D Cani et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Fecal bacteriotherapy for recurrent Clostridium difficile infection

(2009) Johan S. Bakken   ANAEROBE

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Toll-like receptor 2 is critical for induction of Reg3  expression and intestinal clearance of Yersinia pseudotuberculosis

(2009) R Dessein et al.   GUT

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

The role of innate signaling in the homeostasis of tolerance and immunity in the intestine

(2009) Jerry M. Wells et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice

(2009) Chenhong Zhang et al.   ISME Journal

Effect ofLactobacillus gasseriBNR17 on blood glucose levels and body weight in a mouse model of type 2 diabetes

(2009) S.I. Yun et al.   JOURNAL OF APPLIED MICROBIOLOGY

Probiotics and prebiotics for severe acute malnutrition (PRONUT study): a double-blind efficacy randomised controlled trial in Malawi

(2009) Marko Kerac et al.   LANCET

Adjustment of dosing of antimicrobial agents for bodyweight in adults

(2009) Matthew E Falagas et al.   LANCET

Probiotics – little evidence for a link to obesity

(2009) S. Dusko Ehrlich   NATURE REVIEWS MICROBIOLOGY

No causal link between obesity and probiotics

(2009) Nathalie Delzenne et al.   NATURE REVIEWS MICROBIOLOGY

Probiotics and obesity: a link?

(2009) Didier Raoult   NATURE REVIEWS MICROBIOLOGY

Microbiota and SCFA in Lean and Overweight Healthy Subjects

(2009) Andreas Schwiertz et al.   Obesity

Monitoring Bacterial Community of Human Gut Microbiota Reveals an Increase in Lactobacillus in Obese Patients and Methanogens in Anorexic Patients

(2009) Fabrice Armougom et al.   PLoS One

Milk fermented by Lactobacillus gasseri SBT2055 influences adipocyte size via inhibition of dietary fat absorption in Zucker rats

(2008) Essam M. Hamad et al.   BRITISH JOURNAL OF NUTRITION

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Activation of G Protein-Coupled Receptor 43 in Adipocytes Leads to Inhibition of Lipolysis and Suppression of Plasma Free Fatty Acids

(2008) Hongfei Ge et al.   ENDOCRINOLOGY

Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice

(2008) Mathieu Membrez et al.   FASEB JOURNAL

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing

(2008) Les Dethlefsen et al.   PLOS BIOLOGY