rAAV-mediated overexpression of sox9, TGF-β and IGF-I in minipig bone marrow aspirates to enhance the chondrogenic processes for cartilage repair

Role of Sox9 in Growth Factor Regulation of Articular Chondrocytes

(2015) Shuiliang Shi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Direct bone morphogenetic protein 2 and Indian hedgehog gene transfer for articular cartilage repair using bone marrow coagulates

(2015) J.T. Sieker et al.   OSTEOARTHRITIS AND CARTILAGE

Cartilage Repair and Subchondral Bone Remodeling in Response to Focal Lesions in a Mini-Pig Model: Implications for Tissue Engineering

(2015) Matthew B. Fisher et al.   TISSUE ENGINEERING PART A

Current Progress in Stem Cell-Based Gene Therapy for Articular Cartilage Repair

(2015) Janina Frisch et al.   Current Stem Cell Research & Therapy

Cartilage tissue engineering: Molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction

(2014) Magali Demoor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Clinical outcome of autologous bone marrow aspirates concentrate (BMAC) injection in degenerative arthritis of the knee

(2014) Jae-Do Kim et al.   European Journal of Orthopaedic Surgery and Traumatology

Determination of effective rAAV-mediated gene transfer conditions to support chondrogenic differentiation processes in human primary bone marrow aspirates

(2014) A Rey-Rico et al.   GENE THERAPY

Overexpression of human IGF-I via direct rAAV-mediated gene transfer improves the early repair of articular cartilage defects in vivo

(2014) M Cucchiarini et al.   GENE THERAPY

Determination of the Chondrogenic Differentiation Processes in Human Bone Marrow-Derived Mesenchymal Stem Cells Genetically Modified to Overexpress Transforming Growth Factor-β via Recombinant Adeno-Associated Viral Vectors

(2014) Janina Frisch et al.   HUMAN GENE THERAPY

Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells

(2014) Janina Frisch et al.   Stem Cell Research & Therapy

Evolution of Autologous Chondrocyte Repair and Comparison to Other Cartilage Repair Techniques

(2014) Ashvin K. Dewan et al.   Biomed Research International

PTHrP isoforms have differing effect on chondrogenic differentiation and hypertrophy of mesenchymal stem cells

(2012) Jong-Min Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Direct rAAV SOX9 administration for durable articular cartilage repair with delayed terminal differentiation and hypertrophy in vivo

(2012) Magali Cucchiarini et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells

(2012) Jagadeesh K Venkatesan et al.   Stem Cell Research & Therapy

The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells

(2011) Lei Cao et al.   BIOMATERIALS

Metabolic Activities and Chondrogenic Differentiation of Human Mesenchymal Stem Cells Following Recombinant Adeno-Associated Virus–Mediated Gene Transfer and Overexpression of Fibroblast Growth Factor 2

(2011) Magali Cucchiarini et al.   TISSUE ENGINEERING PART A

SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification

(2010) T. Hattori et al.   DEVELOPMENT

Articular cartilage repair by genetically modified bone marrow aspirate in sheep

(2010) A Ivkovic et al.   GENE THERAPY

Sox9 Family Members Negatively Regulate Maturation and Calcification of Chondrocytes through Up-Regulation of Parathyroid Hormone–related Protein

(2009) Katsuhiko Amano et al.   MOLECULAR BIOLOGY OF THE CELL

Sox9 Inhibits Wnt Signaling by Promoting β-Catenin Phosphorylation in the Nucleus

(2008) Lilia Topol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of chondrogenesis by the transcription factor Sox9

(2008) Haruhiko Akiyama   Modern Rheumatology

Enhanced In Vitro Chondrogenesis of Primary Mesenchymal Stem Cells by Combined Gene Transfer

(2008) Andre F. Steinert et al.   TISSUE ENGINEERING PART A

Morphogenetic and Regulatory Mechanisms During Developmental Chondrogenesis: New Paradigms for Cartilage Tissue Engineering

(2008) Lluís Quintana et al.   TISSUE ENGINEERING PART B-REVIEWS

Transcriptional Control of Mesenchymal Stem Cell Differentiation

(2008) Jess Frith et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY