sRAGE attenuates angiotensin II-induced cardiomyocyte hypertrophy by inhibiting RAGE-NFκB-NLRP3 activation

RAGE-TLR Crosstalk Sustains Chronic Inflammation in Neurodegeneration

(2017) Kazimierz Gąsiorowski et al.   MOLECULAR NEUROBIOLOGY

Serum soluble RAGE level inversely correlates with left ventricular hypertrophy in essential hypertension patients

(2016) Q. Liu et al.   GENETICS AND MOLECULAR RESEARCH

ROS-dependent HMGB1 secretion upregulates IL-8 in upper airway epithelial cells under hypoxic condition

(2016) H J Min et al.   Mucosal Immunology

HMGB1-RAGE Axis Makes No Contribution to Cardiac Remodeling Induced by Pressure-Overload

(2016) Hairuo Lin et al.   PLoS One

Involvement of endoplasmic reticulum stress in angiotensin II-induced NLRP3 inflammasome activation in human renal proximal tubular cells in vitro

(2015) Jing Wang et al.   ACTA PHARMACOLOGICA SINICA

Linking RAGE and Nox in diabetic micro- and macrovascular complications

(2015) C. Koulis et al.   DIABETES & METABOLISM

NLRP3 Deficiency Improves Angiotensin II-Induced Hypertension But Not Fetal Growth Restriction During Pregnancy

(2015) Koumei Shirasuna et al.   ENDOCRINOLOGY

Angiotensin II-induced hypertensive renal inflammation is mediated through HMGB1-TLR4 signaling in rat tubulo-epithelial cells

(2015) Anand R. Nair et al.   EXPERIMENTAL CELL RESEARCH

HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma

(2015) Wei Chi et al.   Journal of Neuroinflammation

Knockout of Toll-Like Receptors 2 and 4 Prevents Renal Ischemia-Reperfusion-Induced Cardiac Hypertrophy in Mice

(2015) Mayra Trentin-Sonoda et al.   PLoS One

S100/Calgranulin-Mediated Inflammation Accelerates Left Ventricular Hypertrophy and Aortic Valve Sclerosis in Chronic Kidney Disease in a Receptor for Advanced Glycation End Products-Dependent Manner

(2014) L. Yan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Quinapril treatment abolishes diabetes-associated atherosclerosis in RAGE/apolipoprotein E double knockout mice

(2014) Anna M.D. Watson et al.   ATHEROSCLEROSIS

Blocking the Receptor for Advanced Glycation End Product Activation Attenuates Autoimmune Myocarditis

(2014) Woo-In Yang et al.   CIRCULATION JOURNAL

Calcitriol modulates receptor for advanced glycation end products (RAGE) in diabetic hearts

(2014) Ting-Wei Lee et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Toll-Like Receptor 4 Upregulation by Angiotensin II Contributes to Hypertension and Vascular Dysfunction through Reactive Oxygen Species Production

(2014) Priscila R. De Batista et al.   PLoS One

Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure

(2013) Akira Funayama et al.   CARDIOVASCULAR RESEARCH

Inhibition of Toll-like receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation

(2013) Lei Wang et al.   CARDIOVASCULAR RESEARCH

The N-glycoform of sRAGE is the key determinant for its therapeutic efficacy to attenuate injury-elicited arterial inflammation and neointimal growth

(2013) Hyun-Jin Tae et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Autophagy Plays an Essential Role in Mediating Regression of Hypertrophy during Unloading of the Heart

(2013) Nirmala Hariharan et al.   PLoS One

Inhibition of neointimal hyperplasia in the rat carotid artery injury model by a HMGB1 inhibitor

(2012) Jing Chen et al.   ATHEROSCLEROSIS

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β

(2012) Nathan A. Bracey et al.   EXPERIMENTAL PHYSIOLOGY

Increased interleukin-1β levels are associated with left ventricular hypertrophy and remodelling following acute ST segment elevation myocardial infarction treated by primary percutaneous coronary intervention

(2012) S. Ørn et al.   JOURNAL OF INTERNAL MEDICINE

Vascular Remodeling and Arterial Calcification Are Directly Mediated by S100A12 (EN-RAGE) in Chronic Kidney Disease

(2011) Joseph Gawdzik et al.   AMERICAN JOURNAL OF NEPHROLOGY

RAGE regulates autophagy and apoptosis following oxidative injury

(2011) Rui Kang et al.   Autophagy

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

(2011) E. Mezzaroma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RAGE and cardiovascular disease

(2010) Chi Young Shim   Frontiers in Bioscience-Landmark

HMGB1 activates nuclear factor-κB signaling by RAGE and increases the production of TNF-α in human umbilical vein endothelial cells

(2010) Zheng-Gang Luan et al.   IMMUNOBIOLOGY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

RAGE signaling in inflammation and arterial aging

(2009) Li Lin   Frontiers in Bioscience-Landmark

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

(2009) S. B. Willingham et al.   JOURNAL OF IMMUNOLOGY

RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes

(2009) M. T. Coughlan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Angiotensin II Regulates Cardiac Hypertrophy via Oxidative Stress but Not Antioxidant Enzyme Activities in Experimental Renovascular Hypertension

(2008) Ariel H. POLIZIO et al.   HYPERTENSION RESEARCH