Insight into vitamin B6 -dependent epilepsy due to PLPBP (previously PROSC ) missense mutations

Studies on cyanobacterial protein PipY shed light on structure, potential functions, and vitamin B6 -dependent epilepsy

(2017) Lorena Tremiño et al.   FEBS LETTERS

Confirmation of mutations inPROSCas a novel cause of vitamin B6-dependent epilepsy

(2017) Barbara Plecko et al.   JOURNAL OF MEDICAL GENETICS

MolProbity: More and better reference data for improved all-atom structure validation

(2017) Christopher J. Williams et al.   PROTEIN SCIENCE

PipY, a Member of the Conserved COG0325 Family of PLP-Binding Proteins, Expands the Cyanobacterial Nitrogen Regulatory Network

(2017) José I. Labella et al.   Frontiers in Microbiology

Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin-B 6 -Dependent Epilepsy

(2016) Niklas Darin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ophthalmic acid accumulation in an Escherichia coli mutant lacking the conserved pyridoxal 5′-phosphate-binding protein YggS

(2016) Tomokazu Ito et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Evidence that COG0325 proteins are involved in PLP homeostasis

(2016) Laurence Prunetti et al.   MICROBIOLOGY-SGM

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Conserved Pyridoxal Protein That Regulates Ile and Val Metabolism

(2013) T. Ito et al.   JOURNAL OF BACTERIOLOGY

Improving the Physical Realism and Structural Accuracy of Protein Models by a Two-Step Atomic-Level Energy Minimization

(2011) Dong Xu et al.   BIOPHYSICAL JOURNAL

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

D-Amino Acids Trigger Biofilm Disassembly

(2010) I. Kolodkin-Gal et al.   SCIENCE

Automated inference of molecular mechanisms of disease from amino acid substitutions

(2009) B. Li et al.   BIOINFORMATICS