Cytosolic HSC20 integrates de novo iron–sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients

Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy

(2017) Yanyan Peng et al.   HUMAN MOLECULAR GENETICS

A synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation

(2017) Nathan B. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biogenesis and functions of mammalian iron-sulfur proteins in the regulation of iron homeostasis and pivotal metabolic pathways

(2017) Tracey A. Rouault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electrochemistry of the [4Fe4S] Cluster in Base Excision Repair Proteins: Tuning the Redox Potential with DNA

(2017) Phillip L. Bartels et al.   LANGMUIR

Structure of human Fe–S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP–ISD11 interactions

(2017) Seth A. Cory et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex

(2017) Michal T. Boniecki et al.   Nature Communications

Maintenance of genome stability by Fanconi anemia proteins

(2017) Anna Palovcak et al.   Cell and Bioscience

The CIA Targeting Complex Is Highly Regulated and Provides Two Distinct Binding Sites for Client Iron-Sulfur Proteins

(2017) Diana C. Odermatt et al.   Cell Reports

Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases

(2017) Ryan Barnes et al.   Genes

Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB

(2016) Nunziata Maio et al.   Cell Metabolism

A Glutaredoxin·BolA Complex Serves as an Iron-Sulfur Cluster Chaperone for the Cytosolic Cluster Assembly Machinery

(2016) Avery G. Frey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis

(2016) Jonathan G Van Vranken et al.   eLife

Emerging critical roles of Fe–S clusters in DNA replication and repair

(2015) Jill O. Fuss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Iron –sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery

(2015) Nunziata Maio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mechanisms of intracellular compartmentalization and disease

(2015) Roland Lill   EUROPEAN JOURNAL OF CELL BIOLOGY

The role of mitochondria and the CIA machinery in the maturation of cytosolic and nuclear iron–sulfur proteins

(2015) Roland Lill et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The deca-GX3 proteins Yae1-Lto1 function as adaptors recruiting the ABC protein Rli1 for iron-sulfur cluster insertion

(2015) Viktoria Désirée Paul et al.   eLife

Cochaperone Binding to LYR Motifs Confers Specificity of Iron Sulfur Cluster Delivery

(2014) Nunziata Maio et al.   Cell Metabolism

Characterization and Interaction Studies of Two Isoforms of the Dual Localized 3-Mercaptopyruvate Sulfurtransferase TUM1 from Humans

(2014) Benjamin Fräsdorf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human CIA2A-FAM96A and CIA2B-FAM96B Integrate Iron Homeostasis and Maturation of Different Subsets of Cytosolic-Nuclear Iron-Sulfur Proteins

(2013) Oliver Stehling et al.   Cell Metabolism

Binding of the Chaperone Jac1 Protein and Cysteine Desulfurase Nfs1 to the Iron-Sulfur Cluster Scaffold Isu Protein Is Mutually Exclusive

(2013) Julia Majewska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis

(2013) Helge Uhrigshardt et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The L-Cysteine Desulfurase NFS1 Is Localized in the Cytosol where it Provides the Sulfur for Molybdenum Cofactor Biosynthesis in Humans

(2013) Zvonimir Marelja et al.   PLoS One

(IscS-IscU)2Complex Structures Provide Insights into Fe2S2Biogenesis and Transfer

(2012) Elodie N. Marinoni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interaction of J-Protein Co-Chaperone Jac1 with Fe–S Scaffold Isu Is Indispensable In Vivo and Conserved in Evolution

(2012) Szymon J. Ciesielski et al.   JOURNAL OF MOLECULAR BIOLOGY

Cross talk between the nuclease and helicase activities of Dna2: role of an essential iron–sulfur cluster domain

(2012) Subhash Pokharel et al.   NUCLEIC ACIDS RESEARCH

MMS19 Assembles Iron-Sulfur Proteins Required for DNA Metabolism and Genomic Integrity

(2012) O. Stehling et al.   SCIENCE

MMS19 Links Cytoplasmic Iron-Sulfur Cluster Assembly to DNA Metabolism

(2012) K. Gari et al.   SCIENCE

Iron–sulphur clusters in nucleic acid processing enzymes

(2011) Malcolm F White et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Leucine Biosynthesis Regulates Cytoplasmic Iron-Sulfur Enzyme Biogenesis in an Atm1p-independent Manner

(2011) Tibor Bedekovics et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes

(2011) Daili J A Netz et al.   Nature Chemical Biology

Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron–sulfur cluster biogenesis

(2010) Helge Uhrigshardt et al.   HUMAN MOLECULAR GENETICS

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biophysical Characterization of the Iron in Mitochondria from Atm1p-DepletedSaccharomyces cerevisiae

(2009) Ren Miao et al.   BIOCHEMISTRY

Mitochondrial Dysfunction Leads to Nuclear Genome Instability via an Iron-Sulfur Cluster Defect

(2009) Joshua R. Veatch et al.   CELL

Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis

(2009) Y. Shi et al.   HUMAN MOLECULAR GENETICS

Dual Localized AtHscB Involved in Iron Sulfur Protein Biogenesis in Arabidopsis

(2009) Xiang Ming Xu et al.   PLoS One

Structure of Human J-type Co-chaperone HscB Reveals a Tetracysteine Metal-binding Domain

(2008) Eduard Bitto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Role for Human Nfs1 in the Cytoplasm

(2008) Zvonimir Marelja et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Nbp35 Is Essential for both Cytosolic Iron-Sulfur Protein Assembly and Iron Homeostasis

(2008) O. Stehling et al.   MOLECULAR AND CELLULAR BIOLOGY

Dre2, a Conserved Eukaryotic Fe/S Cluster Protein, Functions in Cytosolic Fe/S Protein Biogenesis

(2008) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

In vivo iron-sulfur cluster formation

(2008) E. C. Raulfs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA