Protein arginine methyl transferase 1- and Jumonji C domain-containing protein 6-dependent arginine methylation regulate hepatocyte nuclear factor 4 alpha expression and hepatocyte proliferation in mice

Human hepatocellular carcinomas with a periportal phenotype have the lowest potential for early recurrence after curative resection

(2017) Romain Désert et al.   HEPATOLOGY

Protein arginine methyltransferase 1 modulates innate immune responses through regulation of peroxisome proliferator-activated receptor γ-dependent macrophage differentiation

(2017) Irina Tikhanovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alcoholic Liver Disease

(2016) Kartik Joshi et al.   Clinics in Liver Disease

Integrative functional genomic delineation of the cascades of transcriptional changes involved in hepatocellular carcinoma progression

(2016) Vignesh Ramesh et al.   INTERNATIONAL JOURNAL OF CANCER

Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease

(2016) Aditya Ambade et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma

(2016) Allison Eberhardt et al.   Oncotarget

The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis

(2016) Olga Aprelikova et al.   Clinical Epigenetics

Role of Hepatocyte Nuclear Factor 4α (HNF4α) in Cell Proliferation and Cancer

(2015) Chad Walesky et al.   GENE EXPRESSION

Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling

(2015) Irina Tikhanovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

(2015) Hsin-Wei Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammasome activation and function in liver disease

(2015) Gyongyi Szabo et al.   Nature Reviews Gastroenterology & Hepatology

Changing Hepatocellular Carcinoma Incidence and Liver Cancer Mortality Rates in the United States

(2014) Sean F Altekruse et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/ -Catenin Signaling Pathway

(2014) K. E. Mercer et al.   Cancer Prevention Research

Arginine Methylation Facilitates the Recruitment of TOP3B to Chromatin to Prevent R Loop Accumulation

(2014) Yanzhong Yang et al.   MOLECULAR CELL

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

(2014) Supriya K. Saha et al.   NATURE

JMJD6 Regulates ERα Methylation on Arginine

(2014) Coralie Poulard et al.   PLoS One

Regulation of FOXO3 by phosphorylation and methylation in hepatitis C virus infection and alcohol exposure

(2013) Irina Tikhanovich et al.   HEPATOLOGY

Wnt signaling and hepatocarcinogenesis: Molecular targets for the development of innovative anticancer drugs

(2013) Floriane Pez et al.   JOURNAL OF HEPATOLOGY

Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation

(2012) Chad Walesky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Alternatively spliced protein arginine methyltransferase 1 isoform PRMT1v2 promotes the survival and invasiveness of breast cancer cells

(2012) R. Mitchell Baldwin et al.   CELL CYCLE

Protein arginine methyltransferase 1 regulates hepatic glucose production in a FoxO1-dependent manner

(2012) Dahee Choi et al.   HEPATOLOGY

Suppression of Hepatocyte Proliferation by Hepatocyte Nuclear Factor 4α in Adult Mice

(2012) Jessica A. Bonzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global burden of cancer in 2008: a systematic analysis of disability-adjusted life-years in 12 world regions

(2012) Isabelle Soerjomataram et al.   LANCET

Arginine methylation of G3BP1 in response to Wnt3a regulates  -catenin mRNA

(2011) R. K. Bikkavilli et al.   JOURNAL OF CELL SCIENCE

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling

(2011) B Cha et al.   ONCOGENE

Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1

(2011) J.-N. Boeckel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

(2010) Christopher T Jones et al.   NATURE BIOTECHNOLOGY

The Etiology of Hepatocellular Carcinoma and Consequences for Treatment

(2010) A. J. Sanyal et al.   ONCOLOGIST

Dynamic Distribution of Histone H4 Arginine 3 Methylation Marks in the Developing Murine Cortex

(2010) Alexandra Chittka   PLoS One

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

Protein Arginine Methyltransferase 1 Coactivates NF-κB-Dependent Gene Expression Synergistically with CARM1 and PARP1

(2008) Paul O. Hassa et al.   JOURNAL OF MOLECULAR BIOLOGY