A versatile biosynthetic approach to amide bond formation

A chemoenzymatic process for amide bond formation by an adenylating enzyme-mediated mechanism

(2018) Ryotaro Hara et al.   Scientific Reports

Mechanistic Elucidation of Zirconium-Catalyzed Direct Amidation

(2017) Helena Lundberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unique physicochemical and catalytic properties dictated by the B3NO2 ring system

(2017) Hidetoshi Noda et al.   Nature Chemistry

Nonclassical Routes for Amide Bond Formation

(2016) Renata Marcia de Figueiredo et al.   CHEMICAL REVIEWS

Amides in Nature and Biocatalysis

(2016) Julia Pitzer et al.   JOURNAL OF BIOTECHNOLOGY

Boronic acid–DMAPO cooperative catalysis for dehydrative condensation between carboxylic acids and amines

(2016) Kazuaki Ishihara et al.   Chemical Science

Enzymatic Basis of “Hybridity” in Thiomarinol Biosynthesis

(2015) Zachary D. Dunn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic strategies and biocatalysts for amide bond formation: tricks of the trade outside of the ribosome

(2015) Anwesha Goswami et al.   Molecular BioSystems

Hafnium-Catalyzed Direct Amide Formation at Room Temperature

(2015) Helena Lundberg et al.   ACS Catalysis

Catalytic amide formation from non-activated carboxylic acids and amines

(2014) Helena Lundberg et al.   CHEMICAL SOCIETY REVIEWS

Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial

(2014) L Kristin Newby et al.   LANCET

Structural and Biochemical Characterization of an Active ArylamineN-Acetyltransferase Possessing a Non-canonical Cys-His-Glu Catalytic Triad

(2013) Xavier Kubiak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic and chemical characterization of ibuprofen degradation by Sphingomonas Ibu-2

(2013) R. W. Murdoch et al.   MICROBIOLOGY-SGM

Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism

(2013) R. Nasuno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Amidation of Carboxylic Acids Catalyzed by ortho-Iodo Arylboronic Acids: Catalyst Optimization, Scope, and Preliminary Mechanistic Study Supporting a Peculiar Halogen Acceleration Effect

(2012) Nicolas Gernigon et al.   JOURNAL OF ORGANIC CHEMISTRY

Efficient, Chemoenzymatic Process for Manufacture of the Boceprevir Bicyclic [3.1.0]Proline Intermediate Based on Amine Oxidase-Catalyzed Desymmetrization

(2012) Tao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rethinking amide bond synthesis

(2011) Vijaya R. Pattabiraman et al.   NATURE

Umpolung reactivity in amide and peptide synthesis

(2010) Bo Shen et al.   NATURE

Oxidative Amidation and Azidation of Aldehydes by NHC Catalysis

(2010) Suman De Sarkar et al.   ORGANIC LETTERS

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Asymmetric Direct Amide Synthesis by Kinetic Amine Resolution: A Chiral Bifunctional Aminoboronic Acid Catalyzed Reaction between a Racemic Amine and an Achiral Carboxylic Acid

(2008) Kenny Arnold et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of a phenylacetate–CoA ligase fromPenicillium chrysogenum

(2008) Martijn J. Koetsier et al.   BIOCHEMICAL JOURNAL

Amide bond formation: beyond the myth of coupling reagents

(2008) Eric Valeur et al.   CHEMICAL SOCIETY REVIEWS

Production of phenylpropanoid amides in recombinant Escherichia coli

(2008) Kiyoon Kang et al.   METABOLIC ENGINEERING