Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination

The heterogeneous nature of NG2-glia

(2016) F. Viganò et al.   BRAIN RESEARCH

A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights

(2016) Chiara Parravicini et al.   CELLULAR SIGNALLING

Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination

(2016) Z. Ou et al.   JOURNAL OF NEUROSCIENCE

Heterogeneity in oligodendroglia: Is it relevant to mouse models and human disease?

(2016) Isis M. Ornelas et al.   JOURNAL OF NEUROSCIENCE RESEARCH

CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17

(2016) Marta Fumagalli et al.   NEUROPHARMACOLOGY

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

(2016) S. Marques et al.   SCIENCE

The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization

(2015) Marta Fumagalli et al.   GLIA

Oxysterols act as promiscuous ligands of class-A GPCRs: In silico molecular modeling and in vitro validation

(2014) Cristina Sensi et al.   CELLULAR SIGNALLING

Adult Neural Precursor Cells from the Subventricular Zone Contribute Significantly to Oligodendrocyte Regeneration and Remyelination

(2014) Y. L. Xing et al.   JOURNAL OF NEUROSCIENCE

Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned

(2014) Viktoria Gudi et al.   Frontiers in Cellular Neuroscience

Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain

(2013) Francesca Viganò et al.   NATURE NEUROSCIENCE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury

(2013) Heike Franke et al.   Purinergic Signalling

Gender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis

(2012) Alessandro Massella et al.   BMC NEUROSCIENCE

The GPR17 receptor in NG2 expressing cells: Focus on in vivocell maturation and participation in acute trauma and chronic damage

(2011) Enrica Boda et al.   GLIA

Phenotypic Changes, Signaling Pathway, and Functional Correlates of GPR17-expressing Neural Precursor Cells during Oligodendrocyte Differentiation

(2011) Marta Fumagalli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of the new P2Y-like receptor GPR17 during oligodendrocyte precursor cell maturation regulates sensitivity to ATP-induced death

(2010) Stefania Ceruti et al.   GLIA

NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease

(2010) R. B. Tripathi et al.   JOURNAL OF NEUROSCIENCE

The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury

(2009) Stefania Ceruti et al.   BRAIN

Cuprizone induces similar demyelination in male and female C57BL/6 mice and results in disruption of the estrous cycle

(2009) Lorelei C. Taylor et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination

(2009) Ying Chen et al.   NATURE NEUROSCIENCE

The Recently Identified P2Y-Like Receptor GPR17 Is a Sensor of Brain Damage and a New Target for Brain Repair

(2008) Davide Lecca et al.   PLoS One