Cancer-associated rs6983267 SNP and its accompanying long noncoding RNACCAT2induce myeloid malignancies via unique SNP-specific RNA mutations

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2

(2016) Roxana S. Redis et al.   MOLECULAR CELL

Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner

(2015) M. Mochizuki-Kashio et al.   BLOOD

Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205

(2015) H. Hirata et al.   CANCER RESEARCH

Elevated expression of CCAT2 is associated with poor prognosis in esophageal squamous cell carcinoma

(2015) Xuelin Zhang et al.   JOURNAL OF SURGICAL ONCOLOGY

The introduction of RNA-DNA differences underlies interindividual variation in the humanIL12RB1mRNA repertoire

(2015) Amy J. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long noncoding RNA CCAT2 correlates with smoking in esophageal squamous cell carcinoma

(2015) Jie Wang et al.   TUMOR BIOLOGY

CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations

(2015) Roxana S Redis et al.   Oncotarget

Recent developments in myelodysplastic syndromes

(2014) R. Bejar et al.   BLOOD

CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer

(2014) Mantang Qiu et al.   TUMOR BIOLOGY

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation

(2014) Goro Sashida et al.   Nature Communications

RNA–DNA differences in human mitochondria restore ancestral form of 16S ribosomal RNA

(2013) Dan Bar-Yaacov et al.   GENOME RESEARCH

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

(2013) H. Ling et al.   GENOME RESEARCH

Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders

(2013) Tomoya Muto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia

(2012) S. Tanaka et al.   BLOOD

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome

(2012) Zhiyu Peng et al.   NATURE BIOTECHNOLOGY

Principles for the post-GWAS functional characterization of cancer risk loci

(2011) Matthew L Freedman et al.   NATURE GENETICS

Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals

(2011) Young Seok Ju et al.   NATURE GENETICS

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

(2010) A Pellagatti et al.   LEUKEMIA

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

(2010) Thomas Ernst et al.   NATURE GENETICS

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene

(2010) Y Kotake et al.   ONCOGENE

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

(2009) Mark M Pomerantz et al.   NATURE GENETICS

Myelodysplastic Syndromes

(2009) Ayalew Tefferi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert

(2008) Maya Ghoussaini et al.   JNCI-Journal of the National Cancer Institute