A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells
Authors
Keywords
-
Journal
GENOME RESEARCH
Volume 28, Issue 6, Pages 846-858
Publisher
Cold Spring Harbor Laboratory
Online
2018-05-04
DOI
10.1101/gr.227280.117
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hyperactivation of HUSH complex function by Charcot–Marie–Tooth disease mutation in MORC2
- (2017) Iva A Tchasovnikarova et al. NATURE GENETICS
- Taz1-Shelterin Promotes Facultative Heterochromatin Assembly at Chromosome-Internal Sites Containing Late Replication Origins
- (2016) Martin Zofall et al. MOLECULAR CELL
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex
- (2016) Richard T. Timms et al. Cell Reports
- Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase
- (2016) Forest H. Andrews et al. Cell Reports
- A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
- (2016) Konstantinos Tzelepis et al. Cell Reports
- MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs
- (2016) Mélanie A. Eckersley-Maslin et al. Cell Reports
- Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes
- (2016) C. Jake Harris et al. PLoS Genetics
- Restricting retrotransposons: a review
- (2016) John L. Goodier Mobile DNA
- Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells
- (2015) Bin Xia Yang et al. CELL
- Atrx promotes heterochromatin formation at retrotransposons
- (2015) D. Sadic et al. EMBO REPORTS
- The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses
- (2015) Gernot Wolf et al. GENES & DEVELOPMENT
- Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells
- (2015) Simon J. Elsässer et al. NATURE
- Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons
- (2015) Yuki Hatanaka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
- (2015) I. A. Tchasovnikarova et al. SCIENCE
- Identification and characterization of essential genes in the human genome
- (2015) T. Wang et al. SCIENCE
- By recruiting HDAC1, MORC2 suppresses p21 Waf1/Cip1 in gastric cancer
- (2015) Qing Zhang et al. Oncotarget
- ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes
- (2015) Hsiao P.J. Voon et al. Cell Reports
- hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells
- (2015) Peter J. Thompson et al. PLoS Genetics
- DBTMEE: a database of transcriptome in mouse early embryos
- (2014) Sung-Joon Park et al. NUCLEIC ACIDS RESEARCH
- MORC1 represses transposable elements in the mouse male germline
- (2014) William A. Pastor et al. Nature Communications
- BRG1 Is Required for Formation of Senescence-Associated Heterochromatin Foci Induced by Oncogenic RAS or BRCA1 Loss
- (2013) Zhigang Tu et al. MOLECULAR AND CELLULAR BIOLOGY
- Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
- (2013) Hiroko Koike-Yusa et al. NATURE BIOTECHNOLOGY
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System
- (2013) Tim Wang et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Proviral Silencing in Embryonic Cells Is Regulated by Yin Yang 1
- (2013) Sharon Schlesinger et al. Cell Reports
- Active Transposition in Genomes
- (2012) Cheng Ran Lisa Huang et al. Annual Review of Genetics
- MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing
- (2012) G. Moissiard et al. SCIENCE
- MORC2 Signaling Integrates Phosphorylation-Dependent, ATPase-Coupled Chromatin Remodeling during the DNA Damage Response
- (2012) Da-Qiang Li et al. Cell Reports
- Microarray Analysis of LTR Retrotransposon Silencing Identifies Hdac1 as a Regulator of Retrotransposon Expression in Mouse Embryonic Stem Cells
- (2012) Judith Reichmann et al. PLoS Computational Biology
- Indefinite Self-Renewal of ESCs through Myc/Max Transcriptional Complex-Independent Mechanisms
- (2011) Tomoaki Hishida et al. Cell Stem Cell
- DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs
- (2011) Mohammad M. Karimi et al. Cell Stem Cell
- Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
- (2011) Jason Wray et al. NATURE CELL BIOLOGY
- H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing
- (2011) Irina A Maksakova et al. Epigenetics & Chromatin
- Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency
- (2011) Haleh Rafati et al. PLOS BIOLOGY
- KAP1 controls endogenous retroviruses in embryonic stem cells
- (2010) Helen M. Rowe et al. NATURE
- Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
- (2010) Toshiyuki Matsui et al. NATURE
- Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX
- (2010) Yangguang Shao et al. NUCLEIC ACIDS RESEARCH
- Mobilizing diversity: transposable element insertions in genetic variation and disease
- (2010) Kathryn A O'Donnell et al. Mobile DNA
- Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
- (2009) P. Yuan et al. GENES & DEVELOPMENT
- SWI/SNF Deficiency Results in Aberrant Chromatin Organization, Mitotic Failure, and Diminished Proliferative Capacity
- (2009) Ryan J. Bourgo et al. MOLECULAR BIOLOGY OF THE CELL
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Smarcc1/Baf155 Couples Self-Renewal Gene Repression with Changes in Chromatin Structure in Mouse Embryonic Stem Cells
- (2009) Christoph Schaniel et al. STEM CELLS
- How Shelterin Protects Mammalian Telomeres
- (2008) Wilhelm Palm et al. Annual Review of Genetics
- The telosome/shelterin complex and its functions
- (2008) Huawei Xin et al. GENOME BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More