hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells

Histone methyltransferase SETDB1 is required for prostate cancer cell proliferation, migration and invasion

(2014) Ying-Hao Sun et al.   ASIAN JOURNAL OF ANDROLOGY

Setdb1is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells

(2014) Sheng Liu et al.   GENES & DEVELOPMENT

An Arginine-rich Motif of Ring Finger Protein 4 (RNF4) Oversees the Recruitment and Degradation of the Phosphorylated and SUMOylated Krüppel-associated Box Domain-associated Protein 1 (KAP1)/TRIM28 Protein during Genotoxic Stress

(2014) Ching-Ying Kuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1

(2014) D. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The diversity of zinc-finger genes on human chromosome 19 provides an evolutionary mechanism for defense against inherited endogenous retroviruses

(2013) S Lukic et al.   CELL DEATH AND DIFFERENTIATION

The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair

(2013) Alexander J Garvin et al.   EMBO REPORTS

Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation

(2013) H. Neyret-Kahn et al.   GENOME RESEARCH

Heterogeneous Nuclear Ribonucleoprotein (HnRNP) K Genome-wide Binding Survey Reveals Its Role in Regulating 3′-End RNA Processing and Transcription Termination at the Early Growth Response 1 (EGR1) Gene through XRN2 Exonuclease

(2013) Michal Mikula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterogeneous Nuclear Ribonucleoprotein K Supports Vesicular Stomatitis Virus Replication by Regulating Cell Survival and Cellular Gene Expression

(2013) P. X. Dinh et al.   JOURNAL OF VIROLOGY

Protein synthesis rate is the predominant regulator of protein expression during differentiation

(2013) A. R. Kristensen et al.   Molecular Systems Biology

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

(2013) M Rodriguez-Paredes et al.   ONCOGENE

Zfp819, a novel KRAB-zinc finger protein, interacts with KAP1 and functions in genomic integrity maintenance of mouse embryonic stem cells

(2013) Xiaoying Tan et al.   Stem Cell Research

Distinct roles of KAP1, HP1 and G9a/GLP in silencing of the two-cell-specific retrotransposon MERVL in mouse ES cells

(2013) Irina A Maksakova et al.   Epigenetics & Chromatin

Proviral Silencing in Embryonic Cells Is Regulated by Yin Yang 1

(2013) Sharon Schlesinger et al.   Cell Reports

The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

(2012) Hendrik Marks et al.   CELL

SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage

(2012) Seong Won Lee et al.   EMBO JOURNAL

DNA Damage-induced Heterogeneous Nuclear Ribonucleoprotein K SUMOylation Regulates p53 Transcriptional Activation

(2012) Federico Pelisch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs

(2011) Mohammad M. Karimi et al.   Cell Stem Cell

Direct Recruitment of ERK Cascade Components to Inducible Genes Is Regulated by Heterogeneous Nuclear Ribonucleoprotein (hnRNP) K

(2011) Michal Mikula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Analysis of KAP1 Genomic Recruitment

(2011) S. Iyengar et al.   MOLECULAR AND CELLULAR BIOLOGY

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

(2011) Craig J. Ceol et al.   NATURE

Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

(2011) Fuchou Tang et al.   PLoS One

Silencing of endogenous retroviruses: when and why do histone marks predominate?

(2011) Danny C. Leung et al.   TRENDS IN BIOCHEMICAL SCIENCES

H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing

(2011) Irina A Maksakova et al.   Epigenetics & Chromatin

Higher Expression of the Heterogeneous Nuclear Ribonucleoprotein K in Melanoma

(2010) Fushi Wen et al.   ANNALS OF SURGICAL ONCOLOGY

Repression of Retrotransposal Elements in Mouse Embryonic Stem Cells Is Primarily Mediated by a DNA Methylation-independent Mechanism

(2010) Leah K. Hutnick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

(2010) Toshiyuki Matsui et al.   NATURE

Heterogeneous nuclear ribonucleoprotein K: altered pattern of expression associated with diagnosis and prognosis of prostate cancer

(2009) P Barboro et al.   BRITISH JOURNAL OF CANCER

Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate

(2009) Isao Fukuda et al.   CHEMISTRY & BIOLOGY

SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state

(2009) S. Bilodeau et al.   GENES & DEVELOPMENT

Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells

(2009) P. Yuan et al.   GENES & DEVELOPMENT

Proteomics Analysis Reveals Overlapping Functions of Clustered Protocadherins

(2009) Meng-Hsuan Han et al.   MOLECULAR & CELLULAR PROTEOMICS

Embryonic stem cells use ZFP809 to silence retroviral DNAs

(2009) Daniel Wolf et al.   NATURE

Windei, the Drosophila Homolog of mAM/MCAF1, Is an Essential Cofactor of the H3K9 Methyl Transferase dSETDB1/Eggless in Germ Line Development

(2009) Carmen M. Koch et al.   PLoS Genetics

Endogenous retroviruses

(2008) C. Stocking et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structural insights into human KAP1 PHD finger–bromodomain and its role in gene silencing

(2008) Lei Zeng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY