ZP2 pathogenic variants cause in vitro fertilization failure and female infertility

Loss-of-function mutations in TDRD7 lead to a rare novel syndrome combining congenital cataract and nonobstructive azoospermia in humans

(2017) Yue-Qiu Tan et al.   GENETICS IN MEDICINE

A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans

(2014) Matteo A. Avella et al.   JOURNAL OF CELL BIOLOGY

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Mutant ZP1 in Familial Infertility

(2014) Hua-Lin Huang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

(2013) Liying Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mammalian zona pellucida glycoproteins: structure and function during fertilization

(2012) Satish K. Gupta et al.   CELL AND TISSUE RESEARCH

HomozygosityMapper2012--bridging the gap between homozygosity mapping and deep sequencing

(2012) D. Seelow et al.   NUCLEIC ACIDS RESEARCH

National, Regional, and Global Trends in Infertility Prevalence Since 1990: A Systematic Analysis of 277 Health Surveys

(2012) Maya N. Mascarenhas et al.   PLOS MEDICINE

ZP2 and ZP3 cytoplasmic tails prevent premature interactions and ensure incorporation into the zona pellucida

(2011) M. Jimenez-Movilla et al.   JOURNAL OF CELL SCIENCE

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Gamete Recognition in Mice Depends on the Cleavage Status of an Egg's Zona Pellucida Protein

(2010) G. Gahlay et al.   SCIENCE

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS