Let's fight cancer: let-7 is a tool to enhance antitumor immune responses

Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells

(2017) Alexandria C Wells et al.   eLife

A U.S. "Cancer Moonshot" to accelerate cancer research

(2016) D. S. Singer et al.   SCIENCE

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function

(2015) Leonid A Pobezinsky et al.   NATURE IMMUNOLOGY

T cell exclusion, immune privilege, and the tumor microenvironment

(2015) J. A. Joyce et al.   SCIENCE

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

(2014) Isobel S. Okoye et al.   IMMUNITY

microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells

(2014) Antoine Marcais et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mechanism of Dis3l2 substrate recognition in the Lin28–let-7 pathway

(2014) Christopher R. Faehnle et al.   NATURE

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA let-7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis

(2012) Hongbing Guan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

Proinflammatory Role forlet-7MicroRNAS in Experimental Asthma

(2010) Sumanth Polikepahad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY

let-7 microRNAs in development, stem cells and cancer

(2008) Ingo Büssing et al.   TRENDS IN MOLECULAR MEDICINE