In silico approaches for investigating the binding propensity of apigenin and luteolin against class I HDAC isoforms
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
In silico approaches for investigating the binding propensity of apigenin and luteolin against class I HDAC isoforms
Authors
Keywords
-
Journal
Future Medicinal Chemistry
Volume -, Issue -, Pages -
Publisher
Future Science, LTD
Online
2018-07-11
DOI
10.4155/fmc-2018-0020
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis
- (2017) Chien-Yi Lu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Characterizing the Chemical Space of ERK2 Kinase Inhibitors Using Descriptors Computed from Molecular Dynamics Trajectories
- (2017) Jeremy Ash et al. Journal of Chemical Information and Modeling
- Predicting the Effect of Amino Acid Single-Point Mutations on Protein Stability—Large-Scale Validation of MD-Based Relative Free Energy Calculations
- (2017) Thomas Steinbrecher et al. JOURNAL OF MOLECULAR BIOLOGY
- Adverse drug reactions triggered by the common HLA-B*57:01 variant: a molecular docking study
- (2017) George Van Den Driessche et al. Journal of Cheminformatics
- In-Silico Drug discovery approach targeting receptor tyrosine kinase-like orphan receptor 1 for cancer treatment
- (2017) Onkar Nath et al. Scientific Reports
- Histone deacetylase inhibitor sulforaphane: The phytochemical with vibrant activity against prostate cancer
- (2016) Shabir Ahmad Ganai BIOMEDICINE & PHARMACOTHERAPY
- Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia
- (2016) Elena Ceccacci et al. BRITISH JOURNAL OF CANCER
- Novel Approaches Towards Designing of Isoform-Selective Inhibitors Against Class II Histone Deacetylases: The Acute Requirement for Targetted Anticancer Therapy
- (2016) Shabir Ahmad Ganai CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1expression
- (2016) Tsui-Hwa Tseng et al. ENVIRONMENTAL TOXICOLOGY
- Histone deacetylase inhibitor givinostat: the small-molecule with promising activity against therapeutically challenging haematological malignancies
- (2016) Shabir Ahmad Ganai JOURNAL OF CHEMOTHERAPY
- Structure of ‘linkerless’ hydroxamic acid inhibitor-HDAC8 complex confirms the formation of an isoform-specific subpocket
- (2016) Alexa A. Tabackman et al. JOURNAL OF STRUCTURAL BIOLOGY
- Modulating epigenetic HAT activity for reinstating acetylation homeostasis: A promising therapeutic strategy for neurological disorders
- (2016) Shabir Ahmad Ganai et al. PHARMACOLOGY & THERAPEUTICS
- A Comprehensive In Silico Analysis on the Structural and Functional Impact of SNPs in the Congenital Heart Defects Associated with NKX2-5 Gene—A Molecular Dynamic Simulation Approach
- (2016) Firoz Abdul Samad et al. PLoS One
- Histone deacetylase inhibitors in hematological malignancies and solid tumors
- (2015) Pusoon Chun ARCHIVES OF PHARMACAL RESEARCH
- Strategy for enhancing the therapeutic efficacy of histone deacetylase inhibitor dacinostat: the novel paradigm to tackle monotonous cancer chemoresistance
- (2015) Shabir Ahmad Ganai ARCHIVES OF PHARMACAL RESEARCH
- Structural studies on molecular mechanisms of Nelfinavir resistance caused by non-active site mutation V77I in HIV-1 protease
- (2015) Ankita Gupta et al. BMC BIOINFORMATICS
- Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway
- (2015) Chia-Hung Lin et al. BMC CANCER
- Panobinostat: The Small Molecule Metalloenzyme Inhibitor with Marvelous Anticancer Activity
- (2015) Shabir Ahmad Ganai CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Targeting protein kinase and DNA molecules by diimine–phthalate complexes in antiproliferative activity
- (2015) Narayanaperumal Pravin et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Discovery of a latent calcineurin inhibitory peptide from its autoinhibitory domain by docking, dynamic simulation, andin vitromethods
- (2015) B. M. Harish et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins
- (2015) Edward Harder et al. Journal of Chemical Theory and Computation
- Anticancer potential of the histone deacetylase inhibitor-like effects of flavones, a subclass of polyphenolic compounds: a review
- (2015) Prabhat Singh et al. MOLECULAR BIOLOGY REPORTS
- Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents
- (2015) Madhusoodanan Mottamal et al. MOLECULES
- Energy-optimised pharmacophore approach to identify potential hotspots during inhibition of Class II HDAC isoforms
- (2014) Shabir Ahmad Ganai et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- HDAC inhibition through valproic acid modulates the methylation profiles in human embryonic kidney cells
- (2014) Shabir Ahmad Ganai et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Erasers of Histone Acetylation: The Histone Deacetylase Enzymes
- (2014) E. Seto et al. Cold Spring Harbor Perspectives in Biology
- Differential expression of histone deacetylases HDAC1, 2 and 3 in human breast cancer - overexpression of HDAC2 and HDAC3 is associated with clinicopathological indicators of disease progression
- (2013) Berit Maria Müller et al. BMC CANCER
- Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability
- (2013) Benjamin E. L. Lauffer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
- (2013) G. Madhavi Sastry et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates
- (2013) Christopher J. Millard et al. MOLECULAR CELL
- Energy based pharmacophore mapping of HDAC inhibitors against class I HDAC enzymes
- (2012) Subha Kalyaanamoorthy et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- A Phase I Pharmacokinetic and Pharmacodynamic Study of CHR-3996, an Oral Class I Selective Histone Deacetylase Inhibitor in Refractory Solid Tumors
- (2012) U. Banerji et al. CLINICAL CANCER RESEARCH
- HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins
- (2012) Kwang Hwa Jung et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Structure of HDAC3 bound to co-repressor and inositol tetraphosphate
- (2012) Peter J. Watson et al. NATURE
- Molecular Dynamics Simulations Suggest Ligand’s Binding to Nicotinamidase/Pyrazinamidase
- (2012) Ji-Long Zhang et al. PLoS One
- Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: In vitro and in vivo study
- (2011) Mitali Pandey et al. MOLECULAR CARCINOGENESIS
- The VSGB 2.0 model: A next generation energy model for high resolution protein structure modeling
- (2011) Jianing Li et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
- (2010) María Berdasco et al. DEVELOPMENTAL CELL
- Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans
- (2010) Sabine Lagger et al. EMBO JOURNAL
- The role of histone deacetylases in prostate cancer
- (2010) Ata Abbas et al. Epigenetics
- Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells
- (2010) Samir Attoub et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Advances and Challenges in Protein-Ligand Docking
- (2010) Sheng-You Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Virtual Fragment Docking by Glide: a Validation Study on 190 Protein−Fragment Complexes
- (2010) Márk Sándor et al. Journal of Chemical Information and Modeling
- Towards the comprehensive, rapid, and accurate prediction of the favorable tautomeric states of drug-like molecules in aqueous solution
- (2010) Jeremy R. Greenwood et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Challenges and advances in computational docking: 2009 in review
- (2010) Elizabeth Yuriev et al. JOURNAL OF MOLECULAR RECOGNITION
- HDAC2 negatively regulates memory formation and synaptic plasticity
- (2009) Ji-Song Guan et al. NATURE
- Aberrant Epigenetic Silencing Is Triggered by a Transient Reduction in Gene Expression
- (2009) Jon A. Oyer et al. PLoS One
- HDAC6 is a target for protection and regeneration following injury in the nervous system
- (2009) M. A. Rivieccio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6
- (2009) A. Gibbs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone Deacetylase 8 in Neuroblastoma Tumorigenesis
- (2008) I. Oehme et al. CLINICAL CANCER RESEARCH
- Histone deacetylase inhibitors in lymphoma and solid malignancies
- (2008) Walid Rasheed et al. Expert Review of Anticancer Therapy
- Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity
- (2008) Anja Schuetz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinomain vitroandin vivo
- (2008) Jon Jones et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment
- (2008) C. Colussi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HDAC3 overexpression and colon cancer cell proliferation and differentiation
- (2007) Colleen C. Spurling et al. MOLECULAR CARCINOGENESIS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started