Predicting the Effect of Amino Acid Single-Point Mutations on Protein Stability—Large-Scale Validation of MD-Based Relative Free Energy Calculations

Title
Predicting the Effect of Amino Acid Single-Point Mutations on Protein Stability—Large-Scale Validation of MD-Based Relative Free Energy Calculations
Authors
Keywords
protein stability, protein engineering, molecular dynamics, protein folding
Journal
JOURNAL OF MOLECULAR BIOLOGY
Volume 429, Issue 7, Pages 948-963
Publisher
Elsevier BV
Online
2016-12-10
DOI
10.1016/j.jmb.2016.12.007

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