Integrative omics analysis of p53-dependent regulation of metabolism

Census and evaluation of p53 target genes

(2017) M Fischer   ONCOGENE

Integrated omics analyses of retrograde signaling mutant delineate interrelated stress-response strata

(2017) Marta Bjornson et al.   PLANT JOURNAL

Cancer Metabolism: Fueling More than Just Growth

(2016) Namgyu Lee et al.   MOLECULES AND CELLS

PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements

(2016) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of –omics findings

(2016) Agnieszka Latosinska et al.   Scientific Reports

Regulation of Cellular Metabolism and Hypoxia by p53

(2016) Timothy J. Humpton et al.   Cold Spring Harbor Perspectives in Medicine

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway

(2016) Derek A. Franklin et al.   Scientific Reports

Tumor suppressor p53 and its mutants in cancer metabolism

(2015) Juan Liu et al.   CANCER LETTERS

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

(2015) Giovanni Ciriello et al.   CELL

MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis

(2015) Hiroshi Tsugawa et al.   NATURE METHODS

Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities

(2015) Madhusudhan Kollareddy et al.   Nature Communications

Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor

(2015) Esha Madan et al.   Oncotarget

Metabolic control of cell death

(2014) D. R. Green et al.   SCIENCE

A Comprehensive and High-Resolution Genome-wide Response of p53 to Stress

(2014) Gue Su Chang et al.   Cell Reports

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

(2014) Mary Ann Allen et al.   eLife

Metabolic Regulation by p53 Family Members

(2013) Celia R. Berkers et al.   Cell Metabolism

Metabolic targets for cancer therapy

(2013) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa

(2013) Liz J. Valente et al.   Cell Reports

Characterization of the p53 Cistrome – DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions

(2013) Katharina Schlereth et al.   PLoS Genetics

A p53-inducible microRNA-34a downregulates Ras signaling by targeting IMPDH

(2012) Hwa-Ryeon Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DAVID-WS: a stateful web service to facilitate gene/protein list analysis

(2012) X. Jiao et al.   BIOINFORMATICS

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence

(2012) Tongyuan Li et al.   CELL

Metabolic regulation of oxygen and redox homeostasis by p53: Lessons from evolutionary biology?

(2012) Jie Zhuang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of lipid metabolism by p53 – fighting two villains with one sword

(2012) Ido Goldstein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Redox Control and Interplay Between p53 Isoforms: Roles in the Regulation of Basal p53 Levels, Cell Fate, and Senescence

(2011) Hind Hafsi et al.   ANTIOXIDANTS & REDOX SIGNALING

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

(2011) S. Serra et al.   BLOOD

Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial

(2011) Sirwan Hadad et al.   BREAST CANCER RESEARCH AND TREATMENT

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Role of p53 Serine 46 in p53 Target Gene Regulation

(2011) Leonie Smeenk et al.   PLoS One

The role of p53 in cell metabolism

(2010) Xing-ding Zhang et al.   ACTA PHARMACOLOGICA SINICA

p53, Aerobic Metabolism, and Cancer

(2010) Cory U. Lago et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation and Functional Contribution of Thymidine Kinase 1 in Repair of DNA Damage

(2010) Yen-Ling Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

MDM2-Dependent Downregulation of p21 and hnRNP K Provides a Switch between Apoptosis and Growth Arrest Induced by Pharmacologically Activated p53

(2009) Martin Enge et al.   CANCER CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Regulation of p53R2 and its role as potential target for cancer therapy

(2008) Xin Wang et al.   CANCER LETTERS

In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute

(2008) E M Michalak et al.   CELL DEATH AND DIFFERENTIATION