Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis

Enhancing Recovery From Sepsis

(2018) Hallie C. Prescott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Preservation of CGRP in myocardium attenuates development of cardiac dysfunction in diabetic rats

(2016) Tao Sun et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD

(2016) Jianmin Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitogen‐Activated Protein Kinase and Intracellular Polyamine Signaling Is Involved in TRPV1 Activation–Induced Cardiac Hypertrophy

(2016) Mai Chen et al.   Journal of the American Heart Association

Cytochrome P450 epoxygenase pathway of polyunsaturated fatty acid metabolism

(2015) Arthur A. Spector et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Activation of TRPV1 attenuates high salt-induced cardiac hypertrophy through improvement of mitochondrial function

(2015) Hongmei Lang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Vascular Expression of Transient Receptor Potential Vanilloid 1 (TRPV1)

(2015) Claire A. Sand et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function

(2015) Vasundhara Kain et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO–TRPA1–CGRP signalling pathway

(2015) Mirjam Eberhardt et al.   Nature Communications

Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue

(2014) Romain A. Colas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload–induced maladaptive cardiac remodeling

(2014) Jin Endo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Plasma somatostatin-like immunoreactivity increases in the plasma of septic patients and rats with systemic inflammatory reaction: Experimental evidence for its sensory origin and protective role

(2014) Balazs Suto et al.   PEPTIDES

Gender Dimorphism of the Cardiac Dysfunction in Murine Sepsis: Signalling Mechanisms and Age-Dependency

(2014) Jianmin Chen et al.   PLoS One

Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1

(2014) Camilla Fusi et al.   Nature Communications

TRPV1 Ablation Aggravates Inflammatory Responses and Organ Damage during Endotoxic Shock

(2013) Youping Wang et al.   Clinical and Vaccine Immunology

Activation of Neuronal Transient Receptor Potential Vanilloid 1 Channel Underlies 20-Hydroxyeicosatetraenoic Acid–Induced Vasoactivity

(2013) Kristen J. Bubb et al.   HYPERTENSION

Systemic Disease during Streptococcus pneumoniae Acute Lung Infection Requires 12-Lipoxygenase-Dependent Inflammation

(2013) R. Bhowmick et al.   JOURNAL OF IMMUNOLOGY

TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids

(2013) Erhu Cao et al.   NEURON

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of Cardiac Dysfunction in Sepsis

(2013) Ahmed Zaky et al.   SHOCK

20-Hydroxyeicosatetraenoic Acid (20-HETE) Is a Novel Activator of Transient Receptor Potential Vanilloid 1 (TRPV1) Channel

(2012) Hairuo Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPV1 Deletion Enhances Local Inflammation and Accelerates the Onset of Systemic Inflammatory Response Syndrome

(2012) E. S. Fernandes et al.   JOURNAL OF IMMUNOLOGY

Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

(2011) D. J. Cavanaugh et al.   JOURNAL OF NEUROSCIENCE

Activation of TRPV1 by Dietary Capsaicin Improves Endothelium-Dependent Vasorelaxation and Prevents Hypertension

(2010) Dachun Yang et al.   Cell Metabolism

Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis*

(2010) Seah-Fang Ang et al.   CRITICAL CARE MEDICINE

Modulation of single-channel properties of TRPV1 by phosphorylation

(2010) Milena Studer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Activation of Akt/GSK-3β signaling pathway is involved in intermedin1–53 protection against myocardial apoptosis induced by ischemia/reperfusion

(2009) Jun-Qiu Song et al.   APOPTOSIS

Decreased Expression of Transient Receptor Potential Vanilloid 1 Impaires the Postischemic Recovery of Diabetic Mouse Hearts

(2009) Zhonghai Wei et al.   CIRCULATION JOURNAL

Involvement of afferent neurons in the pathogenesis of endotoxin-induced ileus in mice: Role of CGRP and TRPV1 receptors

(2009) Benedicte Y. De Winter et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TRPV1-mediated protection against endotoxin-induced hypotension and mortality in rats

(2008) Youping Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cinnamyl-3,4-dihydroxy-α-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase

(2008) Ying-Zi Gong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tissue-Specific Regulation of Microvascular Diameter: Opposite Functional Roles of Neuronal and Smooth Muscle Located Vanilloid Receptor-1

(2008) T. Kark et al.   MOLECULAR PHARMACOLOGY