A role for heat shock factor 1 in hypercapnia-induced inhibition of inflammatory cytokine expression

Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome

(2017) Nicolas Nin et al.   INTENSIVE CARE MEDICINE

Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1

(2016) Nikolai Hentze et al.   eLife

Identification ofDrosophilaZfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference Screen

(2015) Iiro Taneli Helenius et al.   JOURNAL OF IMMUNOLOGY

Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection

(2015) Sharadha Dayalan Naidu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

HSF1 at a glance

(2014) A. Vihervaara et al.   JOURNAL OF CELL SCIENCE

Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in MurinePseudomonasPneumonia

(2013) Khalilah L. Gates et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

Toll-like Receptor Agonists and Febrile Range Hyperthermia Synergize to Induce Heat Shock Protein 70 Expression and Extracellular Release

(2012) Aditi Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Predictors of 1-Year Mortality at Hospital Admission for Acute Exacerbations of Chronic Obstructive Pulmonary Disease

(2012) R.H.J. Slenter et al.   RESPIRATION

Heat Shock Factor 1 Protects against Lung Mycoplasma pneumoniae Infection in Mice

(2011) Fabienne Gally et al.   Journal of Innate Immunity

Firefly luciferase mutants as sensors of proteome stress

(2011) Rajat Gupta et al.   NATURE METHODS

Whole-Genome Analysis Reveals That Active Heat Shock Factor Binding Sites Are Mostly Associated with Non-Heat Shock Genes in Drosophila melanogaster

(2011) Sarah E. Gonsalves et al.   PLoS One

Epithelial Cell Death Is an Important Contributor to Oxidant-mediated Acute Lung Injury

(2010) G. R. Scott Budinger et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Elevated CO2 selectively inhibits interleukin-6 and tumor necrosis factor expression and decreases phagocytosis in the macrophage

(2010) Naizhen Wang et al.   FASEB JOURNAL

Heat Shock Factor 1 Protects Mice from Rapid Death duringListeria monocytogenesInfection by Regulating Expression of Tumor Necrosis Factor Alpha during Fever

(2010) Patience Murapa et al.   INFECTION AND IMMUNITY

Heat Shock Transcription Factor 1 Localizes to Sex Chromatin during Meiotic Repression

(2010) Malin Åkerfelt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF- B Links CO2 Sensing to Innate Immunity and Inflammation in Mammalian Cells

(2010) E. P. Cummins et al.   JOURNAL OF IMMUNOLOGY

Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury*

(2009) Donall F. O’Croinin et al.   CRITICAL CARE MEDICINE

Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis

(2009) Alistair D. Nichol et al.   CRITICAL CARE MEDICINE

Heat Shock Transcription Factor 1 Inhibits Expression of IL-6 through Activating Transcription Factor 3

(2009) R. Takii et al.   JOURNAL OF IMMUNOLOGY

Lower respiratory infections by adenovirus in children. Clinical features and risk factors for bronchiolitis obliterans and mortality

(2009) Patricia Murtagh et al.   PEDIATRIC PULMONOLOGY

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection

(2009) I. T. Helenius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Complex III-generated Oxidants Activate ASK1 and JNK to Induce Alveolar Epithelial Cell Death following Exposure to Particulate Matter Air Pollution

(2008) Saul Soberanes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat shock factor 1 inhibits nuclear factor–κB nuclear binding activity during endotoxin tolerance and heat shock

(2008) Mingchen Song et al.   JOURNAL OF CRITICAL CARE