Nutritional regimens with periodically recurring phases of dietary restriction extend lifespan in Drosophila

Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease

(2017) Min Wei et al.   Science Translational Medicine

The conserved role of protein restriction in aging and disease

(2016) Hamed Mirzaei et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila

(2016) Julia Hoffmann et al.   Aging-US

Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster

(2016) Rachel Whitaker et al.   Aging-US

Octopamine controls starvation resistance, life span and metabolic traits in Drosophila

(2016) Yong Li et al.   Scientific Reports

Expression analysis of octopamine and tyramine receptors in Drosophila

(2015) Samar El-Kholy et al.   CELL AND TISSUE RESEARCH

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan

(2015) Sebastian Brandhorst et al.   Cell Metabolism

Insulin/IGF signaling and its regulation in Drosophila

(2015) Dick R. Nässel et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Time-restricted feeding attenuates age-related cardiac decline in Drosophila

(2015) S. Gill et al.   SCIENCE

Effects of nutritional components on aging

(2014) Dongyeop Lee et al.   AGING CELL

Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population

(2014) Morgan E. Levine et al.   Cell Metabolism

Fasting: Molecular Mechanisms and Clinical Applications

(2014) Valter D. Longo et al.   Cell Metabolism

Quantifying Drosophila food intake: comparative analysis of current methodology

(2014) Sonali A Deshpande et al.   NATURE METHODS

Caloric restriction mimetics: towards a molecular definition

(2014) Frank Madeo et al.   NATURE REVIEWS DRUG DISCOVERY

Drosophila Insulin-Producing Cells Are Differentially Modulated by Serotonin and Octopamine Receptors and Affect Social Behavior

(2014) Jiangnan Luo et al.   PLoS One

Protein and amino acid restriction, aging and disease: from yeast to humans

(2014) Hamed Mirzaei et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

(2014) Ricki J. Colman et al.   Nature Communications

A Genetic Strategy to Measure Circulating Drosophila Insulin Reveals Genes Regulating Insulin Production and Secretion

(2014) Sangbin Park et al.   PLoS Genetics

Noninvasive Analysis of Microbiome Dynamics in the Fruit Fly Drosophila melanogaster

(2013) Christine Fink et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Local requirement of the Drosophila insulin binding protein imp-L2 in coordinating developmental progression with nutritional conditions

(2013) Ladan Sarraf-Zadeh et al.   DEVELOPMENTAL BIOLOGY

High carbohydrate–low protein consumption maximizes Drosophila lifespan

(2013) Kimberley D. Bruce et al.   EXPERIMENTAL GERONTOLOGY

Drosophila Cytokine Unpaired 2 Regulates Physiological Homeostasis by Remotely Controlling Insulin Secretion

(2012) Akhila Rajan et al.   CELL

Effect of dietary restriction on metabolic, anatomic and molecular traits in mice depends on the initial level of basal metabolic rate

(2012) P. Brzek et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Greater insulin sensitivity in calorie restricted rats occurs with unaltered circulating levels of several important myokines and cytokines

(2012) Naveen Sharma et al.   Nutrition & Metabolism

Reliable Drosophila Body Fat Quantification by a Coupled Colorimetric Assay

(2011) Anja Hildebrandt et al.   PLoS One

Insulin Injection and Hemolymph Extraction to Measure Insulin Sensitivity in Adult Drosophila melanogaster

(2011) Aaron T. Haselton et al.   Jove-Journal of Visualized Experiments

Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor

(2010) Nazif Alic et al.   AGING CELL

Partial ablation of adult Drosophilainsulin-producing neurons modulates glucose homeostasis and extends life span without insulin resistance

(2010) Aaron Haselton et al.   CELL CYCLE

Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network

(2010) Linda Partridge et al.   EXPERIMENTAL GERONTOLOGY

Remote Control of Insulin Secretion by Fat Cells in Drosophila

(2009) Charles Géminard et al.   Cell Metabolism

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

(2009) A. A. Soukas et al.   GENES & DEVELOPMENT

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Water- and nutrient-dependent effects of dietary restriction on Drosophila lifespan

(2009) W. W. Ja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Molecular architecture of the fruit fly's airway epithelial immune system

(2008) Christina Wagner et al.   BMC GENOMICS

Lifespan and reproduction in Drosophila: New insights from nutritional geometry

(2008) K. P. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA