Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia

Prediction of Preeclampsia Using the Soluble fms-Like Tyrosine Kinase 1 to Placental Growth Factor RatioNovelty and Significance

(2017) Ulla Sovio et al.   HYPERTENSION

The decidua of preeclamptic-like BPH/5 mice exhibits an exaggerated inflammatory response during early pregnancy

(2017) C.Y. Heyward et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The sFlt-1/PlGF ratio as a predictor for poor pregnancy and neonatal outcomes

(2017) Yu-Shan Chang et al.   Pediatrics and Neonatology

Dynamic maternal and fetal Notch activity and expression in placentation

(2017) Heather I. Levin et al.   PLACENTA

Diagnosis of preeclampsia and fetal growth restriction with the sFlt-1/PlGF ratio: Diagnostic accuracy of the automated immunoassay Kryptor®

(2017) Lisa Antonia Dröge et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Expression of the complement system's activation factors in plasma of patients with early/late-onset severe pre-eclampsia

(2016) Yingdong He et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Hypoxic Stress Forces Irreversible Differentiation of a Majority of Mouse Trophoblast Stem Cells Despite FGF4

(2016) Y. Yang et al.   BIOLOGY OF REPRODUCTION

Correlations between complement system’s activation factors and anti-angiogenesis factors in plasma of patients with early/late-onset severe preeclampsia

(2016) Yingdong He et al.   HYPERTENSION IN PREGNANCY

Pathophysiology of preeclampsia: an angiogenic imbalance and long-lasting systemic vascular dysfunction

(2016) Takuji Tomimatsu et al.   HYPERTENSION RESEARCH

Splenic RNA and MicroRNA Mimics Promote Complement Factor B Production and Alternative Pathway Activation via Innate Immune Signaling

(2016) Lin Zou et al.   JOURNAL OF IMMUNOLOGY

Gestational food restriction decreases placental interleukin-10 expression and markers of autophagy and endoplasmic reticulum stress in murine intrauterine growth restriction

(2016) Alison Chu et al.   NUTRITION RESEARCH

Association of first-trimester angiogenic factors with placental histological findings in late-onset preeclampsia

(2016) Stefania Triunfo et al.   PLACENTA

Preeclampsia, biomarkers, syncytiotrophoblast stress, and placental capacity

(2015) Christopher W.G. Redman et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Increased risk for the development of preeclampsia in obese pregnancies: weighing in on the mechanisms

(2015) Frank T. Spradley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Prevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental Insufficiency

(2015) Shari E. Gelber et al.   JOURNAL OF IMMUNOLOGY

The complement system and adverse pregnancy outcomes

(2015) Jean F. Regal et al.   MOLECULAR IMMUNOLOGY

Expression of RGC32 in human normal and preeclamptic placentas and its role in trophoblast cell invasion and migration

(2015) Q.-j. Wang et al.   PLACENTA

Role of decidual natural killer cells, interleukin-15, and interferon-γ in placental development and preeclampsia

(2014) Jenny L. Sones et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Pre-eclampsia and cardiovascular disease

(2014) C. W. Chen et al.   CARDIOVASCULAR RESEARCH

Endometrial VEGF induces placental sFLT1 and leads to pregnancy complications

(2014) Xiujun Fan et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel expression of EGFL7 in placental trophoblast and endothelial cells and its implication in preeclampsia

(2014) Lauretta A. Lacko et al.   MECHANISMS OF DEVELOPMENT

In Vivo Experiments Reveal the Good, the Bad and the Ugly Faces of sFlt-1 in Pregnancy

(2014) Gabor Szalai et al.   PLoS One

Complement Activation and Regulation in Preeclamptic Placenta

(2014) Anna Inkeri Lokki et al.   Frontiers in Immunology

The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP

(2014) A.L. Tranquilli et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Response gene to complement 32 deficiency causes impaired placental angiogenesis in mice

(2013) Xiao-Bing Cui et al.   CARDIOVASCULAR RESEARCH

VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy

(2013) Minah Kim et al.   EMBO Molecular Medicine

Urinary Excretion of C5b-9 in Severe Preeclampsia

(2013) Richard M. Burwick et al.   HYPERTENSION

Placental growth factor (PlGF): a key to optimizing fetal growth

(2013) Nikolaos Vrachnis et al.   Journal of Maternal-Fetal & Neonatal Medicine

Hypertension in Pregnancy

(2013)   OBSTETRICS AND GYNECOLOGY

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Prepregnancy obesity and complement system activation in early pregnancy and the subsequent development of preeclampsia

(2012) Anne M. Lynch et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Autoantibody-Mediated Complement C3a Receptor Activation Contributes to the Pathogenesis of Preeclampsia

(2012) Wei Wang et al.   HYPERTENSION

ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension

(2012) Colin N. Young et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Mechanisms of implantation: strategies for successful pregnancy

(2012) Jeeyeon Cha et al.   NATURE MEDICINE

Eculizumab for the treatment of preeclampsia/HELLP syndrome

(2012) R.M. Burwick et al.   PLACENTA

Maternal Mortality From Preeclampsia/Eclampsia

(2012) Labib Ghulmiyyah et al.   SEMINARS IN PERINATOLOGY

Role of Complement Component C1q in the Onset of Preeclampsia in Mice

(2011) Jameel Singh et al.   HYPERTENSION

Adenoviral Delivery of VEGF 121 Early in Pregnancy Prevents Spontaneous Development of Preeclampsia in BPH/5 Mice

(2010) Ashley K. Woods et al.   HYPERTENSION

Targeted inhibition of complement activation prevents features of preeclampsia in mice

(2010) Xiaoping Qing et al.   KIDNEY INTERNATIONAL

Early Elevations of the Complement Activation Fragment C3a and Adverse Pregnancy Outcomes

(2010) Anne M. Lynch et al.   OBSTETRICS AND GYNECOLOGY

A systematic, multidisciplinary approach to address the reproductive needs of HIV-seropositive women

(2010) Nataki C Douglas et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) Functions to Promote Uterine Decidual Angiogenesis during Early Pregnancy in the Mouse

(2009) Nataki C. Douglas et al.   ENDOCRINOLOGY

Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia

(2008) Anne M. Lynch et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Complement activation fragment Bb in early pregnancy and spontaneous preterm birth

(2008) Anne M. Lynch et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Role of response gene to complement 32 in diseases

(2008) Sonia I. Vlaicu et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Placental Origins of Preeclampsia

(2008) Berthold Huppertz   HYPERTENSION

Chronic Tempol Prevents Hypertension, Proteinuria, and Poor Feto-Placental Outcomes in BPH/5 Mouse Model of Preeclampsia

(2008) Darren S. Hoffmann et al.   HYPERTENSION

The C5b-9 Membrane Attack Complex of Complement Activation Localizes to Villous Trophoblast Injury in vivo and Modulates Human Trophoblast Function in vitro

(2008) R. Rampersad et al.   PLACENTA