Past, present and future of in vitro 3D reconstructed inflammatory skin models to study psoriasis

Inhibition of IL-17–committed T cells in a murine psoriasis model by a vitamin D analogue

(2018) Nobuhiro Kusuba et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

In vitro psoriasis models with focus on reconstructed skin models as promising tools in psoriasis research

(2017) Eline Desmet et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity

(2017) Hanna Niehues et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal Differentiation

(2017) Mrinal K. Sarkar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

(2017) Susan H. Smith et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models

(2017) Jos P. H. Smits et al.   Scientific Reports

CD1a on Langerhans cells controls inflammatory skin disease

(2016) Ji Hyung Kim et al.   NATURE IMMUNOLOGY

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines

(2016) Conor M. Henry et al.   Cell Reports

Skin-on-a-chip model simulating inflammation, edema and drug-based treatment

(2016) Maierdanjiang Wufuer et al.   Scientific Reports

MUTZ-3 derived Langerhans cells in human skin equivalents show differential migration and phenotypic plasticity after allergen or irritant exposure

(2015) Ilona J. Kosten et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis

(2015) Xianbo Zuo et al.   Nature Communications

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

(2015) Lam C. Tsoi et al.   Nature Communications

Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance

(2015) William R. Swindell et al.   Genome Medicine

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

(2014) E. Glitzner et al.   EMBO Molecular Medicine

Genetically modified animals as models of the pathological processes in psoriasis

(2014) A. G. Soboleva et al.   MOLECULAR BIOLOGY

IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model

(2014) Andrea Chiricozzi et al.   PLoS One

Psoriasis

(2014) P. Di Meglio et al.   Cold Spring Harbor Perspectives in Medicine

Crosstalk between Keratinocytes and T Cells in a 3D Microenvironment: A Model to Study Inflammatory Skin Diseases

(2013) Ellen H. van den Bogaard et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mechanistic Insights from Animal Models of Psoriasis and Psoriatic Arthritis

(2013) Joshua E. Weitz et al.   Current Rheumatology Reports

Co-culture of healthy human keratinocytes and T-cells promotes keratinocyte chemokine production and RORγt-positive IL-17 producing T-cell populations

(2012) Jorieke H. Peters et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Pathological crosstalk in vitro between T lymphocytes and lesional keratinocytes in psoriasis: necessity of direct cell-to-cell contact

(2012) Guillaume Martin et al.   LABORATORY INVESTIGATION

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Meta-Analysis Derived (MAD) Transcriptome of Psoriasis Defines the “Core” Pathogenesis of Disease

(2012) Suyan Tian et al.   PLoS One

Effective Treatment of Psoriasis with Narrow-Band UVB Phototherapy Is Linked to Suppression of the IFN and Th17 Pathways

(2011) Emőke Rácz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interleukin-1 from epithelial cells fosters T cell-dependent skin inflammation

(2010) J. Renne et al.   BRITISH JOURNAL OF DERMATOLOGY

Primary human keratinocytes efficiently induce IL-1-dependent IL-17 in CCR6+ T cells

(2010) Philipp Muhr et al.   EXPERIMENTAL DERMATOLOGY

Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1 , and TNF-  Recapitulates Some Features of Psoriasis

(2010) K. Guilloteau et al.   JOURNAL OF IMMUNOLOGY

Assessment of the Psoriatic Transcriptome in a Large Sample: Additional Regulated Genes and Comparisons with In Vitro Models

(2010) Johann E. Gudjonsson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Psoriasis: what we have learned from mouse models

(2010) Erwin F. Wagner et al.   Nature Reviews Rheumatology

Molecular diagnostics of psoriasis, atopic dermatitis, allergic contact dermatitis and irritant contact dermatitis

(2009) M. Kamsteeg et al.   BRITISH JOURNAL OF DERMATOLOGY

Expression of the Vanin Gene Family in Normal and Inflamed Human Skin: Induction by Proinflammatory Cytokines

(2009) Patrick A.M. Jansen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis

(2009) Erin G. Harper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

(2009) Rafael de Cid et al.   NATURE GENETICS

Development and Validation of Human Psoriatic Skin Equivalents

(2008) Geuranne Tjabringa et al.   AMERICAN JOURNAL OF PATHOLOGY

Development of an in vitro psoriatic skin model by tissue engineering

(2008) Jessica Jean et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Genetically Programmed Differences in Epidermal Host Defense between Psoriasis and Atopic Dermatitis Patients

(2008) Patrick L. J. M. Zeeuwen et al.   PLoS One

A chemical method for fast and sensitive detection of DNA synthesis in vivo

(2008) A. Salic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA