QiDiTangShen Granules Reduced Diabetic Kidney Injury by Regulating the Phosphorylation Balance of the Tyrosine and Serine Residues of Insulin Receptor Substrate 1

Effect of echinacoside on kidney fibrosis by inhibition of TGF-β1/Smads signaling pathway in the db/db mice model of diabetic nephropathy

(2017) Fengjuan Tang et al.   Drug Design Development and Therapy

Transcriptional Profile of Kidney from Type 2 Diabetic db/db Mice

(2017) Haojun Zhang et al.   Journal of Diabetes Research

Diabetic nephropathy: Time to withhold development and progression - A review

(2017) Usama A.A. Sharaf El Din et al.   Journal of Advanced Research

Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase

(2016) Kyle D. Copps et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effect of Liuwei Dihuang decoction on PI3K/Akt signaling pathway in liver of type 2 diabetes mellitus (T2DM) rats with insulin resistance

(2016) Bing Dai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mulberry anthocyanin extract ameliorates insulin resistance by regulating PI3K/AKT pathway in HepG2 cells and db/db mice

(2016) Fujie Yan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Telmisartan reduces atrial arrhythmia susceptibility through the regulation of RAS–ERK and PI3K–Akt–eNOS pathways in spontaneously hypertensive rats

(2015) Wei-wei Wang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes

(2015) Bhesh Sharma et al.   Journal of Translational Medicine

Advanced glycation end products induce glomerular endothelial cell hyperpermeability by upregulating matrix metalloproteinase activity

(2015) PENGLI LUO et al.   Molecular Medicine Reports

1-Deoxynojirimycin Alleviates Insulin Resistance via Activation of Insulin Signaling PI3K/AKT Pathway in Skeletal Muscle of db/db Mice

(2015) Qingpu Liu et al.   MOLECULES

Role of Src in Vascular Hyperpermeability Induced by Advanced Glycation End Products

(2015) Weijin Zhang et al.   Scientific Reports

Insulin and Metabolic Stress Stimulate Multisite Serine/Threonine Phosphorylation of Insulin Receptor Substrate 1 and Inhibit Tyrosine Phosphorylation

(2014) Nancy J. Hançer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent advances in our understanding of insulin signalling to the podocyte

(2013) A. Lay et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Simvastatin Alleviates Hyperpermeability of Glomerular Endothelial Cells in Early-Stage Diabetic Nephropathy by Inhibition of RhoA/ROCK1

(2013) Hui Peng et al.   PLoS One

Tissue–Specific Insulin Signaling, Metabolic Syndrome, and Cardiovascular Disease

(2012) Christian Rask-Madsen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The use of animal models in diabetes research

(2012) Aileen JF King   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

p38 Mitogen-Activated Protein Kinase-Dependent Transactivation of ErbB Receptor Family: A Novel Common Mechanism for Stress-Induced IRS-1 Serine Phosphorylation and Insulin Resistance

(2011) R. Hemi et al.   DIABETES

Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice

(2011) Xiao Yu et al.   EMBO JOURNAL

Early growth response-1 induction by fibroblast growth factor-1 via increase of mitogen-activated protein kinase and inhibition of protein kinase B in hippocampal neurons

(2010) Alexander H Benz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function

(2010) Gavin I. Welsh et al.   Cell Metabolism

C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: Role of mitogen-activated protein kinases

(2010) Liang Xi et al.   HEPATOLOGY

Seeing the Yin and Yang in Cell Biology

(2010) Xueliang Zhu   MOLECULAR BIOLOGY OF THE CELL