Recent advances in our understanding of insulin signalling to the podocyte

Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes

(2013) Nicolas Drapeau et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Renal Protective Effects of Toll-like Receptor 4 Signaling Blockade in Type 2 Diabetic Mice

(2013) J. J. Cha et al.   ENDOCRINOLOGY

Deletion of the Insulin Receptor in the Proximal Tubule Promotes Hyperglycemia

(2013) S. Tiwari et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Adiponectin Promotes Functional Recovery after Podocyte Ablation

(2013) J. M. Rutkowski et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy

(2013) Pengchao Du et al.   KIDNEY INTERNATIONAL

AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

(2013) Guillaume Canaud et al.   NATURE MEDICINE

Insulin signalling to the kidney in health and disease

(2012) Lorna J. Hale et al.   CLINICAL SCIENCE

The Adaptor Protein Grb2 Is Not Essential for the Establishment of the Glomerular Filtration Barrier

(2012) Nicolas Bisson et al.   PLoS One

Akt signalling in health and disease

(2011) Ingeborg Hers et al.   CELLULAR SIGNALLING

Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity

(2011) Akira Mima et al.   KIDNEY INTERNATIONAL

Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

(2010) Mohan R. Dasu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function

(2010) Gavin I. Welsh et al.   Cell Metabolism

Effects of insulin and high glucose on mobilization of slo1 BKCa channels in podocytes

(2010) Eun Young Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes

(2010) Mervi E. Hyvönen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1

(2009) R. Lennon et al.   DIABETOLOGIA

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

(2009) Antonino Belfiore et al.   ENDOCRINE REVIEWS

Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure

(2009) Maria D’Apolito et al.   JOURNAL OF CLINICAL INVESTIGATION

The PPAR  Agonist Pioglitazone Ameliorates Aging-Related Progressive Renal Injury

(2009) H.-C. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy

(2009) R. Lennon et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

High Glucose Induces Toll-Like Receptor Expression in Human Monocytes: Mechanism of Activation

(2008) M. R. Dasu et al.   DIABETES

The Role of Inflammatory Cytokines in Diabetic Nephropathy

(2008) J. F. Navarro-Gonzalez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death

(2008) T. Tejada et al.   KIDNEY INTERNATIONAL

Increased Toll-Like Receptor (TLR) 2 and TLR4 Expression in Monocytes from Patients with Type 1 Diabetes: Further Evidence of a Proinflammatory State

(2007) Sridevi Devaraj et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM