Serotonin decreases the production of Th1/Th17 cytokines and elevates the frequency of regulatory CD4+ T-cell subsets in multiple sclerosis patients

Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition

(2018) George Anderson   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Relationship between CD4 Regulatory T Cells and Anergy In Vivo

(2017) Lokesh A. Kalekar et al.   JOURNAL OF IMMUNOLOGY

Fatigue favors in vitro Th1 and Th17-like cell expansion and reduces corticoid sensitivity in MS patients

(2017) Hélcio Alvarenga-Filho et al.   JOURNAL OF NEUROIMMUNOLOGY

Melatonin reduces inflammatory response in peripheral T helper lymphocytes from relapsing-remitting multiple sclerosis patients

(2017) Nuria Álvarez-Sánchez et al.   JOURNAL OF PINEAL RESEARCH

Melatonin signaling in T cells: Functions and applications

(2017) Wenkai Ren et al.   JOURNAL OF PINEAL RESEARCH

IL-22 promotes Fas expression in oligodendrocytes and inhibits FOXP3 expression in T cells by activating the NF-κB pathway in multiple sclerosis

(2017) Jin Zhen et al.   MOLECULAR IMMUNOLOGY

The influence of gut-derived CD39 regulatory T cells in CNS demyelinating disease

(2017) Javier Ochoa-Repáraz et al.   Translational Research

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

(2017) Chai K. Lim et al.   Scientific Reports

Serotonin Is Involved in Autoimmune Arthritis through Th17 Immunity and Bone Resorption

(2016) Yasmine Chabbi-Achengli et al.   AMERICAN JOURNAL OF PATHOLOGY

The assessment of depression in people with multiple sclerosis: a systematic review of psychometric validation studies

(2016) Daniel Hind et al.   BMC Psychiatry

CD4 + CD25 + regulatory T cells in tumor immunity

(2016) Xin Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis

(2016) Jie Wen et al.   Journal of Neuroimmune Pharmacology

Cancer metastasis: Mechanisms of inhibition by melatonin

(2016) Shih-Chi Su et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Differential Frequency of CD8+ T Cell Subsets in Multiple Sclerosis Patients with Various Clinical Patterns

(2016) Zahra Salehi et al.   PLoS One

Melatonin controls experimental autoimmune encephalomyelitis by altering the T effector/regulatory balance

(2015) Nuria Álvarez-Sánchez et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-17- and interleukin-22-secreting myelin-specific CD4+T cells resistant to corticoids are related with active brain lesions in multiple sclerosis patients

(2015) Ana Cristina Wing et al.   IMMUNOLOGY

Fingolimod does not impair T-cell release from the thymus and beneficially affects Treg function in patients with multiple sclerosis

(2015) Jürgen Haas et al.   Multiple Sclerosis Journal

Fingolimod does not impair T-cell release from the thymus and beneficially affects Treg function in patients with multiple sclerosis

(2015) Jürgen Haas et al.   Multiple Sclerosis Journal

The role of serotonin and its receptors in activation of immune responses and inflammation

(2014) M. S. Shajib et al.   Acta Physiologica

Altered serotonin transporter availability in patients with multiple sclerosis

(2014) Swen Hesse et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Natural Naive CD4 + CD25 + CD127 low Regulatory T Cell (Treg) Development and Function Are Disturbed in Multiple Sclerosis Patients: Recovery of Memory Treg Homeostasis during Disease Progression

(2014) Koen Venken et al.   JOURNAL OF IMMUNOLOGY

Th22 cells are expanded in multiple sclerosis and are resistant to IFN-β

(2014) Simona Rolla et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Potential disease-modifying effects of selective serotonin reuptake inhibitors in multiple sclerosis: systematic review and meta-analysis

(2014) P. Foley et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction

(2014) Marta Kubera et al.   Pharmacological Reports

Inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity reaction by antidepressant drugs

(2014) Katarzyna Curzytek et al.   Pharmacological Reports

Melatonin: Buffering the Immune System

(2013) Antonio Carrillo-Vico et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fine-Tuning of Regulatory T Cell Function: The Role of Calcium Signals and Naive Regulatory T Cells for Regulatory T Cell Deficiency in Multiple Sclerosis

(2013) A. Schwarz et al.   JOURNAL OF IMMUNOLOGY

Fluoxetine Reduces Murine Graft-Versus-Host Disease by Induction of T cell Immunosuppression

(2013) Veerle Gobin et al.   Journal of Neuroimmune Pharmacology

Acute tryptophan depletion in humans: a review of theoretical, practical and ethical aspects

(2013) Simon Young et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Tryptophan: The key to boosting brain serotonin synthesis in depressive illness

(2013) Abdulla A-B Badawy   JOURNAL OF PSYCHOPHARMACOLOGY

Tropisetron diminishes demyelination and disease severity in an animal model of multiple sclerosis

(2013) A. Aminian et al.   NEUROSCIENCE

2010 McDonald criteria for diagnosing pediatric multiple sclerosis

(2012) Yair Sadaka et al.   ANNALS OF NEUROLOGY

IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis

(2012) K. Attridge et al.   BLOOD

A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia

(2012) Ross J. Tynan et al.   BRAIN BEHAVIOR AND IMMUNITY

Genetic variation in the serotonin receptor gene affects immune responses in rheumatoid arthritis

(2012) O Snir et al.   GENES AND IMMUNITY

CD4+CD25+ Regulatory T Cell Depletion Modulates Anxiety and Depression-Like Behaviors in Mice

(2012) Soo-Jeong Kim et al.   PLoS One

High densities of serotonin and peptide YY cells in the colon of patients with lymphocytic colitis

(2012) Magdy El-Salhy   WORLD JOURNAL OF GASTROENTEROLOGY

An Update on Post-infectious Irritable Bowel Syndrome: Role of Genetics, Immune Activation, Serotonin and Altered Microbiome

(2012) Robin Spiller et al.   Journal of Neurogastroenterology and Motility

The many faces of Th17 cells

(2011) Anneli Peters et al.   CURRENT OPINION IN IMMUNOLOGY

Th17 Cell, the New Player of Neuroinflammatory Process in Multiple Sclerosis

(2011) F. Jadidi-Niaragh et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Inflammation, demyelination, and degeneration — Recent insights from MS pathology

(2010) Christine Stadelmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Th1 versus Th17: Are T cell cytokines relevant in multiple sclerosis?

(2010) Amy E. Lovett-Racke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis

(2009) Verena Brucklacher-Waldert et al.   BRAIN

Altered expression of CD4+CD25+ regulatory T cells and its 5-HT1a receptor in patients with major depression disorder

(2009) Yi Li et al.   JOURNAL OF AFFECTIVE DISORDERS

Vitamin D Status Is Positively Correlated with Regulatory T Cell Function in Patients with Multiple Sclerosis

(2009) Joost Smolders et al.   PLoS One

5-Hydroxytryptamine Modulates Migration, Cytokine and Chemokine Release and T-Cell Priming Capacity of Dendritic Cells In Vitro and In Vivo

(2009) Tobias Müller et al.   PLoS One

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

The association of nocturnal serum melatonin levels with major depression in patients with acute multiple sclerosis

(2008) Zehra Akpınar et al.   PSYCHIATRY RESEARCH

Compromised CD4+ CD25highregulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level

(2007) Koen Venken et al.   IMMUNOLOGY