Differential uptake of and sensitivity to diphenhydramine in embryonic and larval zebrafish

In Vitro Biotransformation of Two Human CYP3A Probe Substrates and Their Inhibition during Early Zebrafish Development

(2017) Evy Verbueken et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparison of the In Vivo Biotransformation of Two Emerging Estrogenic Contaminants, BP2 and BPS, in Zebrafish Embryos and Adults

(2017) Vincent Le Fol et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Age matters: Developmental stage of Danio rerio larvae influences photomotor response thresholds to diazinion or diphenhydramine

(2016) Lauren A. Kristofco et al.   AQUATIC TOXICOLOGY

Toxicokinetics of Polar Chemicals in Zebrafish Embryo (Danio rerio): Influence of Physicochemical Properties and of Biological Processes

(2016) Stephan Brox et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Alternative approaches to vertebrate ecotoxicity tests in the 21st century: A review of developments over the last 2 decades and current status

(2016) Adam Lillicrap et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

From the Cover: Zebrafish Larvae Are Insensitive to Stimulation by Cocaine: Importance of Exposure Route and Toxicokinetics

(2016) Krishna Tulasi Kirla et al.   TOXICOLOGICAL SCIENCES

Re-evaluation of animal numbers and costs for in vivo tests to accomplish REACH legislation requirements for chemicals - a report by the Transatlantic Think Tank for Toxicology (t4)

(2016) Costanza Rovida   ALTEX-Alternatives to Animal Experimentation

Fish Embryo Toxicity Test: Identification of Compounds with Weak Toxicity and Analysis of Behavioral Effects To Improve Prediction of Acute Toxicity for Neurotoxic Compounds

(2015) Nils Klüver et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The fish embryo toxicity test as a replacement for the larval growth and survival test: A comparison of test sensitivity and identification of alternative endpoints in zebrafish and fathead minnows

(2015) Marlo K. Sellin Jeffries et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Observed and modeled effects of pH on bioconcentration of diphenhydramine, a weakly basic pharmaceutical, in fathead minnows

(2015) John W. Nichols et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Comparative Pharmacology and Toxicology of Pharmaceuticals in the Environment: Diphenhydramine Protection of Diazinon Toxicity in Danio rerio but Not Daphnia magna

(2014) Lauren A. Kristofco et al.   AAPS Journal

A quantitative HPLC–MS/MS method for studying internal concentrations and toxicokinetics of 34 polar analytes in zebrafish (Danio rerio) embryos

(2014) Stephan Brox et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Influence of the perivitelline space on the quantification of internal concentrations of chemicals in eggs of zebrafish embryos (Danio rerio)

(2014) Stephan Brox et al.   AQUATIC TOXICOLOGY

Dynamics of uptake and elimination of pyrethroid insecticides in zebrafish (Danio rerio) eleutheroembryos

(2014) Wenqing Tu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The fish embryo test (FET): origin, applications, and future

(2014) Thomas Braunbeck et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Bioaccumulation and trophic dilution of human pharmaceuticals across trophic positions of an effluent-dependent wadeable stream

(2014) B. Du et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Diffusion of small molecules into medaka embryos improved by electroporation

(2013) Gerlinde Jung et al.   BMC BIOTECHNOLOGY

The internal concentration of organic substances in fish embryos-A toxicokinetic approach

(2013) Agnes Kühnert et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Comparative pharmaceutical metabolism by rainbow trout (Oncorhynchus mykiss) liver S9 fractions

(2013) Kristin A. Connors et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Use of fish embryo toxicity tests for the prediction of acute fish toxicity to chemicals

(2013) Scott E. Belanger et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Miniaturized extraction methods of triclosan from aqueous and fish roe samples. Bioconcentration studies in zebrafish larvae (Danio rerio)

(2012) R. Gonzalo-Lumbreras et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Predicting Adult Fish Acute Lethality with the Zebrafish Embryo: Relevance of Test Duration, Endpoints, Compound Properties, and Exposure Concentration Analysis

(2012) Melanie Knöbel et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Bioconcentration of pesticides in Zebrafish eleutheroembryos (Danio rerio)

(2012) S. El-Amrani et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Rapid determination of polycyclic aromatic hydrocarbons (PAHs) in zebrafish eleutheroembryos as a model for the evaluation of PAH bioconcentration

(2012) S. El-Amrani et al.   TALANTA

Effects of the antihistamine diphenhydramine on selected aquatic organisms

(2011) Jason P. Berninger et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Spatio-temporal development of CYP1 activity in early life-stages of zebrafish (Danio rerio)

(2010) Jens C. Otte et al.   AQUATIC TOXICOLOGY

Toxicity, uptake kinetics and behavior assessment in zebrafish embryos following exposure to perfluorooctanesulphonicacid (PFOS)

(2010) Haihua Huang et al.   AQUATIC TOXICOLOGY

Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish

(2010) Jared V Goldstone et al.   BMC GENOMICS

Saltatory ontogeny of fishes and sensitive early life stages for ecotoxicology tests

(2009) Scott E. Belanger et al.   AQUATIC TOXICOLOGY

The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research

(2009) Michelle R. Embry et al.   AQUATIC TOXICOLOGY

A novel in vitro system for the determination of bioconcentration factors and the internal dose in zebrafish (Danio rerio) eggs

(2009) René Schreiber et al.   CHEMOSPHERE

OCCURRENCE OF PHARMACEUTICALS AND PERSONAL CARE PRODUCTS IN FISH: RESULTS OF A NATIONAL PILOT STUDY IN THE UNITED STATES

(2009) Alejandro J. Ramirez et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Evolutionary Conservation of Human Drug Targets in Organisms used for Environmental Risk Assessments

(2008) Lina Gunnarsson et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

REACH, non-testing approaches and the urgent need for a change in mind set

(2008) G. Schaafsma et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY