A Randomized, Placebo-Controlled Trial of Lubiprostone for Opioid-Induced Constipation in Chronic Noncancer Pain

Efficacy of Pharmacological Therapies for the Treatment of Opioid-Induced Constipation: Systematic Review and Meta-Analysis

(2013) Alexander C Ford et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Safety and patient outcomes with lubiprostone for up to 52 weeks in patients with irritable bowel syndrome with constipation

(2012) W. D. Chey et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Methadone but not Morphine Inhibits Lubiprostone-Stimulated Cl− Currents in T84 Intestinal Cells and Recombinant Human ClC-2, but not CFTR Cl− Currents

(2012) John Cuppoletti et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Non-Analgesic Effects of Opioids: Management of Opioid-Induced Constipation by Peripheral Opioid Receptor Antagonists: Prevention or Withdrawal?

(2012) Peter Holzer   CURRENT PHARMACEUTICAL DESIGN

Pharmacology of peripheral opioid receptors

(2011) Banafscheh Rachinger-Adam et al.   Current Opinion in Anesthesiology

Long-Term Safety and Effectiveness of Lubiprostone, a Chloride Channel (ClC-2) Activator, in Patients with Chronic Idiopathic Constipation

(2011) Anthony J. Lembo et al.   DIGESTIVE DISEASES AND SCIENCES

Lubiprostone for the treatment of opioid-induced bowel dysfunction

(2011) Banny S Wong et al.   EXPERT OPINION ON PHARMACOTHERAPY

Subcutaneous Methylnaltrexone for Treatment of Opioid-Induced Constipation in Patients With Chronic, Nonmalignant Pain: A Randomized Controlled Study

(2011) Edward Michna et al.   JOURNAL OF PAIN

Lubiprostone Reverses the Inhibitory Action of Morphine on Mucosal Secretion in Human Small Intestine

(2010) Xiaohong Sun et al.   DIGESTIVE DISEASES AND SCIENCES

Efficacy and Safety of Prucalopride in Patients with Chronic Noncancer Pain Suffering from Opioid-Induced Constipation

(2010) Cornelius E. J. Sloots et al.   DIGESTIVE DISEASES AND SCIENCES

Efficacy and Safety of Lubiprostone in Patients with Chronic Constipation

(2009) Charles F. Barish et al.   DIGESTIVE DISEASES AND SCIENCES

Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain

(2009) Roger Chou et al.   JOURNAL OF PAIN

Response to Dr. Kartsonis

(2008) John F. Johanson   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Prevalence, Severity, and Impact of Opioid-Induced Bowel Dysfunction: Results of a US and European Patient Survey (PROBE 1)

(2008) Timothy J. Bell et al.   PAIN MEDICINE