Methadone but not Morphine Inhibits Lubiprostone-Stimulated Cl− Currents in T84 Intestinal Cells and Recombinant Human ClC-2, but not CFTR Cl− Currents

848a Lubiprostone Significantly Improves Treatment Response in Non-Methadone Opioid-Induced Bowel Dysfunction Patients with Chronic, Non-Cancer Pain: Results from a Phase 3, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

(2015) M. Mazen Jamal et al.   GASTROENTEROLOGY

Lubiprostone for the treatment of opioid-induced bowel dysfunction

(2011) Banny S Wong et al.   EXPERT OPINION ON PHARMACOTHERAPY

Lubiprostone Activates Cl− Secretion via cAMP Signaling and Increases Membrane CFTR in the Human Colon Carcinoma Cell Line, T84

(2010) Mei Ao et al.   DIGESTIVE DISEASES AND SCIENCES

Activation of Intestinal Cl− Secretion by Lubiprostone Requires the Cystic Fibrosis Transmembrane Conductance Regulator

(2009) Marcel J.C. Bijvelds et al.   GASTROENTEROLOGY

A synthetic prostone activates apical chloride channels in A6 epithelial cells

(2008) Hui Fang Bao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Development of a generic transient transfection process at 100 L scale

(2008) Ola Tuvesson et al.   CYTOTECHNOLOGY

Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains

(2008) Jennie Garcia-Olivares et al.   JOURNAL OF PHYSIOLOGY-LONDON

Reflections on more than 10 years of TGE approaches

(2008) Sabine Geisse   PROTEIN EXPRESSION AND PURIFICATION