Article
Biotechnology & Applied Microbiology
Si Yang, Chenxi Li, Hongyan Zhan, Rong Liu, Wenliang Chen, Xiaoli Wang, Kexin Xu
Summary: In this study, a label-free fluorescent biosensor for the detection of tetracycline (TET) was developed using specific aptamer-templated silver nanoclusters (AgNCs). The binding of TET to the aptamer led to a conformational change, resulting in the transformation of AgNCs into larger silver nanoparticles (AgNPs) and a decrease in fluorescence. The proposed biosensor exhibited high sensitivity and selectivity for TET detection in milk, with a limit of detection of 11.46 ng/mL and a linear range of 20 ng/mL-10 g/mL. These findings demonstrate the potential of the biosensor for quantitative determination of TET in food samples and expand the application of DNA-AgNCs in related fields.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Chemistry, Analytical
Hongjing Sun, Zheng Liu, Zhihong Li, Xinyue Ma, Zixuan Duan, Chunyan Sun
Summary: A label-free fluorescent sensor based on a specific DNAzyme and thiazole orange was developed for monitoring Pb2+ in water samples. This sensor showed excellent sensitivity, selectivity, and applicability for the analysis of drinking water and river water samples.
ANALYTICAL LETTERS
(2023)
Article
Chemistry, Analytical
Pengfei Ma, Hualin Guo, Nuo Duan, Xiaoyuan Ma, Lin Yue, Qianhui Gu, Zhouping Wang
Summary: The study showed that ionic strength and type influence the recognition of aptamers, with magnesium ion playing a vital role in the binding process. Various methods were used to analyze the binding performance and conformational changes of the aptamer, leading to the development of a label-free fluorescence polarization sensor for detecting chloramphenicol.
Article
Spectroscopy
Lei Liao, Jianglong Yao, Ruo Yuan, Yun Xiang, Bingying Jiang
Summary: In this study, a fluorescence strategy based on transcriptional amplification of lighting-up aptamers was developed for label-free, low background and sensitive monitoring of FEN1, with a low detection limit, allowing for early-stage cancer diagnosis.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Ryan P. Connelly, Pedro F. Madalozzo, Jack E. Mordeson, Andrew D. Pratt, Yulia Gerasimova
Summary: The research demonstrates the conversion of a dapoxyl DNA aptamer into a sensor generating fluorescence signal at different wavelengths for detecting drug-resistant tuberculosis gene fragments. The promiscuity of the aptamer in binding to fluorogenic dyes has been discovered, laying the foundation for its application as a versatile sensing platform.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Samane Naeeminejad, Khalil Abnous, Seyed Mohammad Taghdisi
Summary: The fluorescent aptasensor introduced in this study utilizes the hairpin structure of TOB aptamer to quantitatively monitor tobramycin antibiotic with high sensitivity and a wide linear relationship. It can detect TOB in human serum and milk samples with low detection limits. This sensor has the potential to be used for human diagnostics, food control, and environmental monitoring with its key features of feasibility, simplicity, and high sensitivity.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Applied
Yukun Yang, Lanqing Yang, Yuanyuan Ma, Xiaomin Wang, Jinhua Zhang, Baoqing Bai, Ligang Yu, Caixia Guo, Fuyuan Zhang, Shu Qin
Summary: A label-free point-of-care QCM aptasensing platform based on MOFs and AuNPs was developed for tetracycline detection. The QCM aptasensor, modified with MOFs and AuNPs, exhibited high sensitivity and good selectivity. The sensor showed a wide linear range and low limit of detection for quantitative detection of tetracycline.
Article
Chemistry, Analytical
Yusi Li, Fang Yang, Shunmei Li, Ruo Yuan, Yun Xiang
Summary: The study presents a target-triggered transcription cascade amplification strategy for label-free and sensitive detection of PDGF-BB protein biomarker. The developed method shows high sensitivity and superior selectivity, making it attractive for detecting biomarkers at trace levels.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Hongqin Yang, Lian Xia, Jia Zheng, Zhengmin Xie, Jianli Zhou, Yuangen Wu
Summary: The Clothianidin pesticide not only contaminates the ecological environment, but also poses a potential threat to human health. Therefore, it is crucial to develop efficient and accurate methods for recognizing and detecting the residues of Clothianidin in agricultural products. In this study, an aptamer (named CLO-1) with good selectivity and strong affinity to Clothianidin pesticide was screened for the first time using the Capture-SELEX strategy. The constructed label-free fluorescent aptasensor based on CLO-1 aptamer exhibited high sensitivity and selectivity for the detection of Clothianidin pesticide.
Article
Chemistry, Physical
Zenan Zhao, Simin Cao, Haoyang Li, Dong Li, Yanping He, Xin Wang, Jinquan Chen, Sanjun Zhang, Jianhua Xu, Jay R. Knutson
Summary: This article describes the ultrafast excited-state dynamics of free TO in aqueous solution. The fluorescence lifetime of TO in water was found to be-1 ps, and an additional decay component around 30-40 ps was also observed. Furthermore, this 30-40 ps lifetime component was also present in TO-γ-cyclodextrin (CD) complexes.
Article
Chemistry, Analytical
Hanyue Cui, Jing Yang, Huan Lu, Li Li, Xiaoli Zhu, Yaping Ding
Summary: A label-free fluorescence sensor based on near-infrared carbon dots and aptamer has been developed for the sensitive and selective detection of ciprofloxacin. The sensor showed excellent performance with linear response and low detection limit, and it also demonstrated great potential in biological imaging.
Article
Nanoscience & Nanotechnology
Chengyi Hong, Xiaoxia Zhang, Sishi Ye, Hongfen Yang, Zhiyong Huang, Dan Yang, Ren Cai, Weihong Tan
Summary: The study developed a highly selective and sensitive method for detecting TET, applicable for TET determination in animal-derived foods, with results consistent with commercial ELISA kits.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Xinyue Lan, Longjiao Zhu, Yangzi Zhang, Keren Chen, Jia Wang, Zaihui Du, Shuting Li, Xu Chen, Wentao Xu
Summary: This study proposes a new form of Thioflavin T nucleic acid switches called CHTLNAS, which have excellent fluorescence excitation properties and can achieve label-free and enzyme-free detection of tetracycline and berberine within 10 minutes at the pM level. It can also track intracellular carriers and prolong the nuclear-entry time of Thioflavin T, expanding its application in cell biology research.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Chemistry, Physical
Shringika Soni, Utkarsh Jain, Donald H. Burke, Nidhi Chauhan
Summary: Prescription stimulant drug (PSD) abuse is a global concern, and there is a need for the development of sensitive, rapid, and low-cost kits for on-spot PSD detection. In this study, a gold nanoflower modified, electrochemical aptasensor was successfully developed for Amphetamine (AMP) detection. The aptasensor showed high sensitivity, low limit of detection, and negligible interference from potentially interfering compounds. It was able to accurately detect AMP in spiked urine and water samples.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Applied
Jin'ai Chen, Yuting Jin, Taotao Ren, Shuo Wang, Xianghong Wang, Fuyuan Zhang, Yiwei Tang
Summary: A sensitive and rapid label-free fluorescence assay was developed using a Tb3+ ion-enrofloxacin aptamer coordination probe for specific detection of three fluoroquinolones. The method showed high accuracy and recovery based on experimental results.
Article
Materials Science, Multidisciplinary
Ruifang Su, Jingyue Xu, Yeli Luo, Ying Li, Xin Liu, Jiaxin Bie, Chunyan Sun
Article
Chemistry, Analytical
Xin Liu, Ying Li, Jing Liang, Wenyue Zhu, Jingyue Xu, Ruifang Su, Lei Yuan, Chunyan Sun
Article
Chemistry, Multidisciplinary
Ying Li, Ruifang Su, Jingyue Xu, Jiaxin Bie, Rui Sun, Luokai Wang, Xin Liu, Chunyan Sun
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
(2018)
Article
Spectroscopy
Chuanyu Yang, Jiaxin Bie, Xinmeng Zhang, Caiyun Yan, Hanjie Li, Minghui Zhang, Ruifang Su, Xiaoguang Zhang, Chunyan Sun
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2018)
Article
Biochemical Research Methods
Ruifang Su, Hongru Zheng, Shuyue Dong, Rui Sun, Shangna Qiao, Hongjing Sun, Xinyue Ma, Tiehua Zhang, Chunyan Sun
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
Xinyue Ma, Shangna Qiao, Hongjing Sun, Ruifang Su, Chunyan Sun, Mingdi Zhang
FRONTIERS IN CHEMISTRY
(2019)
Article
Chemistry, Analytical
Zhihong Li, Hongjing Sun, Xinyue Ma, Ruifang Su, Rui Sun, Chuanyu Yang, Chunyan Sun
ANALYTICA CHIMICA ACTA
(2020)
Article
Chemistry, Analytical
Chuanyu Yang, Caiyi Du, Ruifang Su, Junyang Wang, Ying Li, Xinyue Ma, Zhihong Li, Chunyan Sun
Summary: The fluorescent aptasensor based on sensitized terbium(III) luminescence was constructed to detect melamine in milk. The sensor showed low fluorescence intensity of Tb3+ in the absence of melamine, but stronger fluorescence intensity in the presence of melamine, enabling accurate and rapid detection with a detection limit of 0.02 μg/mL.
Article
Chemistry, Multidisciplinary
Hui-Jun Fu, Ruifang Su, Lin Luo, Zi-Jian Chen, Thomas Just Sorensen, Niko Hildebrandt, Zhen-Lin Xu
Summary: The study demonstrates a simple and rapid TG-FRET assay for the quantification of histamine in food. The method allows efficient screening with limits of detection of 0.19 μg/mL and 0.03 μg/mL for two different biosensors, respectively. In addition, the assay shows excellent specificity against structurally similar food components and can be directly applied to food samples.
Article
Chemistry, Multidisciplinary
Ruifang Su, Yu-Tang Wu, Sofia Doulkeridou, Xue Qiu, Thomas Just Sorensen, Kimihiro Susumu, Igor L. Medintz, Paul M. P. van Bergen en Henegouwen, Niko Hildebrandt
Summary: This study demonstrates a biosensing approach that combines nanobodies with nanoparticles, specifically attaching nanobodies with different C-terminal tags to widely used biocompatible semiconductor quantum dots. A rapid and wash-free immunoassay for the epidermal growth factor receptor (EGFR) was designed and implemented by displacing Tb-labeled hexahistidine-tagged nanobodies from the QD surfaces via EGFR-nanobody binding, leading to a concentration-dependent decrease in the Tb-to-QD FRET signal. The detection limit of this assay was 80 +/- 20 pM, which is 10-fold lower than conventional sandwich FRET assays.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Applied
Leping Chen, Yanfen Wang, Tingyu Shi, Tiantian Ma, Yang Li, Huayu Qiu, Shouchun Yin, Meier Gu
Summary: This study successfully overcame the limitations of the heavy atom effect by introducing iodine atoms and innovatively enhancing the structure while weakening stacking behavior, achieving high efficiency and precision in photodynamic therapy and photothermal therapy.
Article
Chemistry, Applied
Bingpeng Guo, Honghan Sa, Peng Zhang, Guiwen Hao, Mengyu Li, Qingqing Jiang, Baoying Li, Wei Shu, Changxiang Shao
Summary: The design of ratiometric fluorescence probes with large Stokes shift is of great significance in detecting and imaging target substances in complex organisms. In this study, a novel fluorophore with a large Stokes shift was easily obtained, and a fluorescence probe based on it demonstrated rapid response, high selectivity, and sensitivity towards peroxynitrite. The probe also showed excellent biocompatibility and remarkable mitochondrial targeting ability, making it suitable for proportional imaging of peroxynitrite in living cells and zebrafish.
Review
Chemistry, Applied
Haidong Huang, Xiaohui Wang, Xinyang Li, Yichen Li, Guojin Liu, Lan Zhou, Jianzhong Shao
Summary: This article introduces the application of responsive photonic crystals in anti-counterfeiting technology, with a focus on the preparation principle, classification, and preparation methods.
Article
Chemistry, Applied
Yunpeng Wang, Tao Zhao, Xiaoye Bi, Chencheng Lv
Summary: In this study, three novel carbene dyes were designed to achieve environmentally friendly dyeing processes. The dyes formed covalent bonds with fibers and exhibited good dyeing performance and high color fastness. These findings highlight the potential of the novel carbene dyes in promoting green production in the textile industry.
Review
Chemistry, Applied
Yizhe Yan, Xiaopei Zhu, Jia-Xin Cao, Yuan He, Shaoqing Li, Jian-Yong Wang
Summary: In this paper, 1,3,5-triazine dyes were successfully synthesized and their photophysical properties were studied. Two probes were selected for further investigation, showing promising applications in various fields.
Article
Chemistry, Applied
Xin Hu, Tongsheng Huang, Lihua Chen, Weifeng Zhu, Fengjie Deng, Xiancai Li, Jianwen Tian, Meiying Liu, Xiaoyong Zhang, Yen Wei
Summary: This study presents the synthesis of fluorescent cyclomatrix polyphosphazene spheres with aggregation-induced emission (AIE) feature and biodegradable potential for controlled drug delivery. The resulting micelles exhibit high water dispersibility, desirable fluorescence performance, and high drug loading capacity. They can effectively release the encapsulated drug in physiological solution and show excellent biological imaging ability and cytotoxicity against cancer cells.
Article
Chemistry, Applied
Yanzhu Liu, Yanghui Lei, Dongyan Li, Guangkui Li, Dongping Li, Yongxiu Li
Summary: In this study, luminescent lanthanide nanoparticles were synthesized as a dual emission turn-off probe for detecting 2,6-pyridinedicarboxylic acid (DPA) in water. The nanoparticles showed good dispersion and water stability, and achieved low detection limits for DPA. They also exhibited high recoveries in various samples.
Article
Chemistry, Applied
Jung Jae Do, Jong Ryeol Kwon, Donghan Kim, Jae Woong Jung
Summary: This study presents a defect passivation approach using coumarin dye as a multi-functional passivating agent of perovskite films to boost power conversion efficiency and operating stability of PSCs. The incorporation of coumarin dye improves the film morphology, enhances carrier extraction/transport, and suppresses trap-assisted recombination in the perovskite films. The optimized device demonstrates impressive reliability and practical applicability, maintaining over 90% of its initial PCE after being exposed to continuous indoor lighting irradiation for 2000 hours.
Article
Chemistry, Applied
Gang Wang, Yu-Chang Wang, Jing Lu, Wen-Fu Yan, Juan Jin, Yuan-Peng Wang, Jia-Jia Zhang, Hui-Jie Zhang, Hao Dong, Xi-Guang Liu
Summary: A new Ni(II) compound with good solid-state fluorescence performance and stability was synthesized, and it showed outstanding detection properties for various substances in aqueous solutions. This compound has the potential to be a multifunctional sensor.
Article
Chemistry, Applied
Luyao Wei, Shenglong Shang, Yu Zheng, Jie Liu, Ping Zhu
Summary: This study developed a facile method to create high saturation and durable structural colors on cotton fabrics. The colors are regulated by adjusting the size of magnetic particles and can be conveniently printed on fabrics using photo masks on transparent films.
Article
Chemistry, Applied
Zhao Jiang, Qing Zhang, Zhaoyu Kong, Ruijie Qiao, Zichuan Liu, Linzhou Song, Senqiang Zhu, Rui Liu, Hongjun Zhu
Summary: Three heteroleptic Ir(III) complexes with different electron-donating aryl groups were synthesized and their optical properties were investigated. It was found that all three complexes exhibited aggregation-induced phosphorescence emission (AIPE) behaviors, and the relationship between the size of organic ligands and AIPE behaviors was characterized. Ir-PhCz showed the best imaging of latent fingerprints due to its green light emission and high quantum yield.
Article
Chemistry, Applied
Zhijun Ruan, Chunxia Fan, Xuanrong Wang, Dong Shao, Xiaodong Yang, Wentao He, Tao Xu, Junqi Lin, Zhengfang Tian
Summary: A novel thioketal-based probe has been designed for rapid and accurate detection of mercury (II) ions, showing different fluorescence characteristics in various states. The probe exhibits excellent selectivity and specificity, making it suitable for Hg2+ detection in water solutions.
Article
Chemistry, Applied
Jianjun Huang, Xuan Zhao, Daniel Escudero, Luc Van Meervelt, Dongbin Zheng, Yuyu Fang, Wim Dehaen
Summary: A series of BOAHY compounds were successfully synthesized and showed versatile applications as a platform for designing novel fluorescent probes, especially in selective recognition.
Article
Chemistry, Applied
Roman V. Larkovich, Victoria E. Shambalova, Savva A. Ponomarev, Alexander S. Aldoshin, Boris N. Tarasevich, Konstantin A. Lyssenko, Valentine G. Nenajdenko
Summary: An efficient synthetic protocol for the preparation of novel 1,7-difluorinated BODIPYs was elaborated. Their photophysical properties were studied and the effect of 2,6-substituents was evaluated using DFT calculations.
Article
Chemistry, Applied
Haneul Kim, Byungjin Koo
Summary: In this study, a lithium ion sensing methodology based on fluorinated naphthalene compounds using 19F NMR and UV-vis spectroscopy is reported. The binding of lithium ions to the compounds is confirmed by changes in chemical shifts and peak broadening. Additionally, the effect of different crown ether ring sizes on the binding ability is observed. This study provides a new method for lithium ion sensing using spectroscopy.