Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis
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Title
Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis
Authors
Keywords
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Journal
Disease Models & Mechanisms
Volume 11, Issue 7, Pages DMM034850
Publisher
The Company of Biologists
Online
2018-05-21
DOI
10.1242/dmm.034850
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Note: Only part of the references are listed.- [10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo
- (2017) Ana Carolina B.M. Martin et al. Oncotarget
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- (2015) Rachel Zoe Carter et al. JOURNAL OF PATHOLOGY
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- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- STC1 expression is associated with tumor growth and metastasis in breast cancer
- (2014) Andy C-M Chang et al. CLINICAL & EXPERIMENTAL METASTASIS
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- (2014) Delphine Denoyer et al. GROWTH FACTORS
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- (2014) Lora C. Bailey-Downs et al. PLoS One
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- (2013) Nuray Erin et al. BREAST CANCER RESEARCH AND TREATMENT
- Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair
- (2013) B Groselj et al. BRITISH JOURNAL OF CANCER
- Novel Modeling of Cancer Cell Signaling Pathways Enables Systematic Drug Repositioning for Distinct Breast Cancer Metastases
- (2013) H. Zhao et al. CANCER RESEARCH
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- (2013) Huan Cai et al. PLoS One
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- (2012) Alastair Hamilton et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Phase I and pharmacodynamic study of an orally administered novel inhibitor of histone deacetylases, SB939, in patients with refractory solid malignancies
- (2011) W. P. Yong et al. ANNALS OF ONCOLOGY
- Inappropriate gene expression in human cancer and its far-reaching biological and clinical significance
- (2011) David Tarin CANCER AND METASTASIS REVIEWS
- Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
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- Combinatorial Effects of Lapatinib and Rapamycin in Triple-Negative Breast Cancer Cells
- (2011) T. Liu et al. MOLECULAR CANCER THERAPEUTICS
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- (2011) V. Novotny-Diermayr et al. MOLECULAR CANCER THERAPEUTICS
- The biology of brain metastases—translation to new therapies
- (2011) April F. Eichler et al. Nature Reviews Clinical Oncology
- Capturing Changes in the Brain Microenvironment during Initial Steps of Breast Cancer Brain Metastasis
- (2010) Mihaela Lorger et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2009) David B. Seligson et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2009) Kan Yonemori et al. CANCER
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- (2008) R. V. Simões et al. MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
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