Mitochondrial DNA Heteroplasmy and Purifying Selection in the Mammalian Female Germ Line
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Title
Mitochondrial DNA Heteroplasmy and Purifying Selection in the Mammalian Female Germ Line
Authors
Keywords
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Journal
DEVELOPMENT GROWTH & DIFFERENTIATION
Volume 60, Issue 1, Pages 21-32
Publisher
Wiley
Online
2018-01-24
DOI
10.1111/dgd.12420
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Related references
Note: Only part of the references are listed.- Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos
- (2018) Vasileios I. Floros et al. NATURE CELL BIOLOGY
- Intra-individual purifying selection on mitochondrial DNA variants during human oogenesis
- (2017) Sara De Fanti et al. HUMAN REPRODUCTION
- Replication Errors Made During Oogenesis Lead to Detectable De Novo mtDNA Mutations in Zebrafish Oocytes with a Low mtDNA Copy Number
- (2016) Auke B. C. Otten et al. GENETICS
- Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck
- (2016) Mingkun Li et al. GENOME RESEARCH
- Mitochondrial DNA sequence characteristics modulate the size of the genetic bottleneck
- (2016) Ian J. Wilson et al. HUMAN MOLECULAR GENETICS
- Reactive oxygen species stimulate mitochondrial allele segregation toward homoplasmy in human cells
- (2016) Feng Ling et al. MOLECULAR BIOLOGY OF THE CELL
- Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing
- (2016) Ana Latorre-Pellicer et al. NATURE
- Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response
- (2016) Yi-Fan Lin et al. NATURE
- Reconstitution in vitro of the entire cycle of the mouse female germ line
- (2016) Orie Hikabe et al. NATURE
- Concise Review: Heteroplasmic Mitochondrial DNA Mutations and Mitochondrial Diseases: Toward iPSC-Based Disease Modeling, Drug Discovery, and Regenerative Therapeutics
- (2016) Hideyuki Hatakeyama et al. STEM CELLS
- A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease
- (2016) Johanna H.K. Kauppila et al. Cell Reports
- Replication Errors Made During Oogenesis Lead to Detectable De Novo mtDNA Mutations in Zebrafish Oocytes with a Low mtDNA Copy Number
- (2016) Auke B. C. Otten et al. GENETICS
- Paths of Heritable Mitochondrial DNA Mutation and Heteroplasmy in Reference and gas-1 Strains of Caenorhabditis elegans
- (2016) Riana I. Wernick et al. Frontiers in Genetics
- Preventing the transmission of mitochondrial DNA disorders using prenatal or preimplantation genetic diagnosis
- (2015) Hubert J.M. Smeets et al. Annals of the New York Academy of Sciences
- A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development
- (2015) Walfred W.C. Tang et al. CELL
- Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile
- (2015) F. Sugawa et al. EMBO JOURNAL
- Quantitative Changes in Gimap3 and Gimap5 Expression Modify Mitochondrial DNA Segregation in Mice
- (2015) R. Jokinen et al. GENETICS
- Mitochondrial DNA haplogroups are associated with severe sepsis and mortality in patients who underwent major surgery
- (2015) Maria Angeles Jiménez-Sousa et al. JOURNAL OF INFECTION
- The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease
- (2015) James B. Stewart et al. NATURE REVIEWS GENETICS
- Protecting the mitochondrial powerhouse
- (2015) Morten Scheibye-Knudsen et al. TRENDS IN CELL BIOLOGY
- Mitochondrial replacement therapy in reproductive medicine
- (2015) Don P. Wolf et al. TRENDS IN MOLECULAR MEDICINE
- Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans
- (2015) Angela Pyle et al. PLoS Genetics
- Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant
- (2014) Jahda H Hill et al. NATURE GENETICS
- Transmission of mitochondrial mutations and action of purifying selection in Drosophila melanogaster
- (2014) Hansong Ma et al. NATURE GENETICS
- Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA
- (2014) B. Rebolledo-Jaramillo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mtDNA Segregation in Heteroplasmic Tissues Is Common In Vivo and Modulated by Haplotype Differences and Developmental Stage
- (2014) Joerg Patrick Burgstaller et al. Cell Reports
- The Challenges of Mitochondrial Replacement
- (2014) Patrick F. Chinnery et al. PLoS Genetics
- Recent Mitochondrial DNA Mutations Increase the Risk of Developing Common Late-Onset Human Diseases
- (2014) Gavin Hudson et al. PLoS Genetics
- Mitochondrial genetics
- (2013) P. F. Chinnery et al. BRITISH MEDICAL BULLETIN
- The role of mitochondrial DNA mutations and free radicals in disease and ageing
- (2013) M. Lagouge et al. JOURNAL OF INTERNAL MEDICINE
- The activity and copy number of mitochondrial DNA in ovine oocytes throughout oogenesis in vivo and during oocyte maturation in vitro
- (2013) Matthew Cotterill et al. MOLECULAR HUMAN REPRODUCTION
- A tripartite transcription factor network regulates primordial germ cell specification in mice
- (2013) Erna Magnúsdóttir et al. NATURE CELL BIOLOGY
- Generation of eggs from mouse embryonic stem cells and induced pluripotent stem cells
- (2013) Katsuhiko Hayashi et al. Nature Protocols
- Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease
- (2013) G. Hudson et al. NEUROLOGY
- No recombination of mtDNA after heteroplasmy for 50 generations in the mouse maternal germline
- (2013) E. Hagstrom et al. NUCLEIC ACIDS RESEARCH
- Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model
- (2013) R. H. Hamalainen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Disease-Causing Mitochondrial Heteroplasmy Segregated Within Induced Pluripotent Stem Cell Clones Derived from a Patient with MELAS
- (2013) Clifford D.L. Folmes et al. STEM CELLS
- Induced Pluripotent Stem Cells with a Mitochondrial DNA Deletion
- (2013) Anne B. C. Cherry et al. STEM CELLS
- Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition
- (2012) Mark S. Sharpley et al. CELL
- Universal heteroplasmy of human mitochondrial DNA
- (2012) B. A. I. Payne et al. HUMAN MOLECULAR GENETICS
- Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission
- (2012) Christoph Freyer et al. NATURE GENETICS
- Minimizing the damage: repair pathways keep mitochondrial DNA intact
- (2012) Lawrence Kazak et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice
- (2012) K. Hayashi et al. SCIENCE
- Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and Humans
- (2010) Passorn Wonnapinij et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups
- (2010) Aurora Gómez-Durán et al. HUMAN MOLECULAR GENETICS
- Segregation of mtDNA throughout human embryofetal development: m.3243A>G as a model system
- (2010) Sophie Monnot et al. HUMAN MUTATION
- Transmission of Mitochondrial DNA Diseases and Ways to Prevent Them
- (2010) Joanna Poulton et al. PLoS Genetics
- New Evidence Confirms That the Mitochondrial Bottleneck Is Generated without Reduction of Mitochondrial DNA Content in Early Primordial Germ Cells of Mice
- (2009) Liqin Cao et al. PLoS Genetics
- Selection against Pathogenic mtDNA Mutations in a Stem Cell Population Leads to the Loss of the 3243A→G Mutation in Blood
- (2008) Harsha Karur Rajasimha et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Pathogenic Mitochondrial DNA Mutations Are Common in the General Population
- (2008) Hannah R. Elliott et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease
- (2008) Rosa Pello et al. HUMAN MOLECULAR GENETICS
- The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes
- (2008) Timothy Wai et al. NATURE GENETICS
- A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes
- (2008) Lynsey M Cree et al. NATURE GENETICS
- Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease
- (2008) James Bruce Stewart et al. NATURE REVIEWS GENETICS
- A comprehensive, non-invasive visualization of primordial germ cell development in mice by the Prdm1-mVenus and Dppa3-ECFP double transgenic reporter
- (2008) Yasuhide Ohinata et al. REPRODUCTION
- A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations
- (2008) Weiwei Fan et al. SCIENCE
- Mitigating Mutational Meltdown in Mammalian Mitochondria
- (2008) David M Rand PLOS BIOLOGY
- Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA
- (2008) James Bruce Stewart et al. PLOS BIOLOGY
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