Peptides derived from the histidine–proline rich glycoprotein bind copper ions and exhibit anti-angiogenic properties

Multitarget trehalose-carnosine conjugates inhibit Aβ aggregation, tune copper(II) activity and decrease acrolein toxicity

(2017) Giuseppa Ida Grasso et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Histidine tracts in human transcription factors: insight into metal ion coordination ability

(2017) Aleksandra Hecel et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

New Insight in Copper-Ion Binding to Human Islet Amyloid: The Contribution of Metal-Complex Speciation To Reveal the Polypeptide Toxicity

(2016) Antonio Magrì et al.   CHEMISTRY-A EUROPEAN JOURNAL

Intracellular Bioinorganic Chemistry and Cross Talk Among Different -Omics

(2016) Diego La Mendola et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The unusual metal ion binding ability of histidyl tags and their mutated derivatives

(2016) Davide Brasili et al.   DALTON TRANSACTIONS

Divalent metal binding by histidine-rich glycoprotein differentially regulates higher order oligomerisation and proteolytic processing

(2016) Kristin M. Priebatsch et al.   FEBS LETTERS

Copper transporters and chaperones: Their function on angiogenesis and cellular signalling

(2016) S R Bharathi Devi et al.   JOURNAL OF BIOSCIENCES

The Inorganic Perspective of VEGF: Interactions of Cu2+ with Peptides Encompassing a Recognition Domain of the VEGF Receptor

(2016) Giulia Grasso et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthesis and Evaluation of Trehalose-Based Compounds as Novel Inhibitors of Cancer Cell Migration and Invasion

(2015) Yong-Li Jiang et al.   Chemical Biology & Drug Design

♦Copper (II) ions modulate Angiogenin activity in human endothelial cells

(2015) Chiara Giacomelli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Behind the Link between Copper and Angiogenesis: Established Mechanisms and an Overview on the Role of Vascular Copper Transport Systems

(2015) Emanuela Urso et al.   JOURNAL OF VASCULAR RESEARCH

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition

(2015) Shun Li et al.   Scientific Reports

Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: implications for angiogenic regulation

(2014) O. Kassaar et al.   BLOOD

Copper as a key regulator of cell signalling pathways

(2014) Alexandra Grubman et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Plasma free fatty acid levels influence Zn2+-dependent histidine-rich glycoprotein-heparin interactions via an allosteric switch on serum albumin

(2014) O. Kassaar et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Copper-dependent and -independent hypoxia-inducible factor-1 regulation of gene expression

(2014) Zhen Zhang et al.   Metallomics

Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse

(2013) S. Jain et al.   ANNALS OF ONCOLOGY

The Syndecan-4/Protein Kinase Cα Pathway Mediates Prostaglandin E2-induced Extracellular Regulated Kinase (ERK) Activation in Endothelial Cells and Angiogenesisin Vivo

(2013) Federico Corti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Copper promotion of angiogenesis in isolated rat aortic ring: role of vascular endothelial growth factor

(2013) Qi-feng Li et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Rapid Copper Acquisition by Developing Murine Mesothelioma: Decreasing Bioavailable Copper Slows Tumor Growth, Normalizes Vessels and Promotes T Cell Infiltration

(2013) Andrew Crowe et al.   PLoS One

CTR1 Silencing Inhibits Angiogenesis by Limiting Copper Entry into Endothelial Cells

(2013) Gomathy Narayanan et al.   PLoS One

Signal Transduction by Vascular Endothelial Growth Factor Receptors

(2013) S. Koch et al.   Cold Spring Harbor Perspectives in Medicine

Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis

(2012) Federica Finetti et al.   BIOCHEMICAL PHARMACOLOGY

The Coordination of NiIIand CuIIIons to the Polyhistidyl Motif of Hpn Protein: Is It as Strong as We Think?

(2012) Danuta Witkowska et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper(II) interaction with peptide fragments of histidine–proline-rich glycoprotein: Speciation, stability and binding details

(2012) Diego La Mendola et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF

(2011) Charlotte Rolny et al.   CANCER CELL

Anti-Angiogenic Peptides for Cancer Therapeutics

(2011) Elena V. Rosca et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Histidine-rich branched peptides as Cu(ii) and Zn(ii) chelators with potential therapeutic application in Alzheimer's disease

(2011) Andrea Lakatos et al.   DALTON TRANSACTIONS

Trehalose: Current Use and Future Applications

(2011) Satoshi Ohtake et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma

(2010) I. K. H. Poon et al.   BLOOD

Copper(ii) complex formation with a linear peptide encompassing the putative cell binding site of angiogenin

(2010) Diego La Mendola et al.   DALTON TRANSACTIONS

Molecular Mediators of Angiogenesis

(2010) Areck A. Ucuzian et al.   Journal of Burn Care & Research

Bridges that guide and unite

(2010) Thomas Schmidt et al.   NATURE

Plasma fatty acid levels may regulate the Zn2+-dependent activities of histidine-rich glycoprotein

(2009) Alan J. Stewart et al.   BIOCHIMIE

Probing the Cu2+ and Zn2+ binding affinity of histidine-rich glycoprotein

(2009) Attila Jancsó et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Copper and nickel binding in multi-histidinic peptide fragments

(2009) Maria Antonietta Zoroddu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Activated Platelets Provide a Functional Microenvironment for the Antiangiogenic Fragment of Histidine-Rich Glycoprotein

(2009) A. Thulin et al.   MOLECULAR CANCER RESEARCH

Histidine-Rich Glycoprotein Can Prevent Development of Mouse Experimental Glioblastoma

(2009) Maria Kärrlander et al.   PLoS One

Complex formation processes of terminally protected peptides containing two or three histidyl residues. Characterization of the mixed metal complexes of peptides

(2008) Snežana Rajković et al.   DALTON TRANSACTIONS

Copper(II) complexes with an avian prion N-terminal region and their potential SOD-like activity

(2008) Diego La Mendola et al.   JOURNAL OF INORGANIC BIOCHEMISTRY