Generation of PTEN knockout bone marrow mesenchymal stem cell lines by CRISPR/Cas9-mediated genome editing

Tetrandrine inhibits the proliferation of human osteosarcoma cells by upregulating the PTEN pathway

(2017) Dong-Dong Tian et al.   ONCOLOGY REPORTS

miR-26a Mediates Adipogenesis of Amniotic Fluid Mesenchymal Stem/Stromal Cells via PTEN, Cyclin E1, and CDK6

(2017) Ourania Trohatou et al.   STEM CELLS AND DEVELOPMENT

miR-92b regulates glioma cells proliferation, migration, invasion, and apoptosis via PTEN/Akt signaling pathway

(2016) Hang Song et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer

(2016) Yan-Ran Wu et al.   TUMOR BIOLOGY

PTEN-mRNA engineered mesenchymal stem cell-mediated cytotoxic effects on U251 glioma cells

(2016) XING RONG GUO et al.   Oncology Letters

MiR-429 increases the metastatic capability of HCC via regulating classic Wnt pathway rather than epithelial–mesenchymal transition

(2015) Jing Tang et al.   CANCER LETTERS

Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway

(2015) Bao-quan Song et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

PTEN/Akt-p27kip1Signaling Promote the BM-MSCs Senescence and Apoptosis in SLE Patients

(2015) Wei Tan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

BMP type I receptor inhibition attenuates endothelial dysfunction in mice with chronic kidney disease

(2015) Hidemi Kajimoto et al.   KIDNEY INTERNATIONAL

The role of COX-2 in mediating the effect of PTEN on BMP9 induced osteogenic differentiation in mouse embryonic fibroblasts

(2014) Jun Huang et al.   BIOMATERIALS

Applications of TALENs and CRISPR/Cas9 in Human Cells and Their Potentials for Gene Therapy

(2014) Jingwen Niu et al.   MOLECULAR BIOTECHNOLOGY

Downregulated microRNA-32 expression induced by high glucose inhibits cell cycle progression via PTEN upregulation and Akt inactivation in bone marrow-derived mesenchymal stem cells

(2013) Guiying Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

The role of microRNA-26b in human adipocyte differentiation and proliferation

(2013) Guixian Song et al.   GENE

TALEN or Cas9 – Rapid, Efficient and Specific Choices for Genome Modifications

(2013) Chuanxian Wei et al.   Journal of Genetics and Genomics

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols