The Endothelin System: A Critical Player in the Pathophysiology of Preeclampsia

Relaxin-mediated renal vasodilation in the rat is associated with falls in glomerular blood pressure

(2018) Aihua Deng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Heme oxygenase-1 is a potent inhibitor of placental ischemia-mediated endothelin-1 production in cultured human glomerular endothelial cells

(2018) Bhavisha A. Bakrania et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Endothelin type B (ET B ) receptors: friend or foe in the pathogenesis of pre-eclampsia and future cardiovascular disease (CVD) risk?

(2018) Katrina M. Mirabito Colafella   CLINICAL SCIENCE

Placental Growth Factor Reduces Blood Pressure in a Uteroplacental Ischemia Model of Preeclampsia in Nonhuman PrimatesNovelty and Significance

(2016) Angela Makris et al.   HYPERTENSION

Sildenafil Treatment Ameliorates the Maternal Syndrome of Preeclampsia and Rescues Fetal Growth in the Dahl Salt–Sensitive Rat

(2016) Ellen E. Gillis et al.   HYPERTENSION

Placental Growth Factor Administration Abolishes Placental Ischemia-Induced HypertensionNovelty and Significance

(2016) Frank T. Spradley et al.   HYPERTENSION

Association Studies Suggest a Key Role for Endothelin-1 in the Pathogenesis of Preeclampsia and the Accompanying Renin–Angiotensin–Aldosterone System SuppressionNovelty and Significance

(2015) Koen Verdonk et al.   HYPERTENSION

Matrix Metalloproteinase 1 Causes Vasoconstriction and Enhances Vessel Reactivity to Angiotensin II via Protease-Activated Receptor 1

(2015) William H. Nugent et al.   Reproductive Sciences

Downregulation of Microvascular Endothelial Type B Endothelin Receptor Is a Central Vascular Mechanism in Hypertensive Pregnancy

(2014) Marc Q. Mazzuca et al.   HYPERTENSION

Drug treatment of hypertension in pregnancy

(2014) Khalid A.J. Al Khaja et al.   JOURNAL OF HYPERTENSION

Maternally sequestered therapeutic polypeptides – a new approach for the management of preeclampsia

(2014) Gene L. Bidwell et al.   Frontiers in Pharmacology

Pathophysiology of hypertension in pre-eclampsia: a lesson in integrative physiology

(2013) A. C. Palei et al.   Acta Physiologica

Enhanced endothelin receptor type B-mediated vasodilation and underlying [Ca2+]iin mesenteric microvessels of pregnant rats

(2013) Marc Q Mazzuca et al.   BRITISH JOURNAL OF PHARMACOLOGY

Recent Advances in the Understanding of the Pathophysiology of Preeclampsia

(2013) Junie P. Warrington et al.   HYPERTENSION

Gestational Hypoxia Induces Preeclampsia-Like Symptoms via Heightened Endothelin-1 Signaling in Pregnant Rats

(2013) Jianjun Zhou et al.   HYPERTENSION

Matrix Metalloproteinase Enhances Big-Endothelin-1 Constriction in Mesenteric Vessels of Pregnant Rats With Reduced Uterine Blood Flow

(2013) Ali Abdalvand et al.   HYPERTENSION

Excess LIGHT Contributes to Placental Impairment, Increased Secretion of Vasoactive Factors, Hypertension, and Proteinuria in Preeclampsia

(2013) Wei Wang et al.   HYPERTENSION

Hypertension in Pregnancy

(2013)   OBSTETRICS AND GYNECOLOGY

Endothelin as a final common pathway in the pathophysiology of preeclampsia

(2012) Eric M. George et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Linking Placental Ischemia and Hypertension in Preeclampsia

(2012) Eric M. George et al.   HYPERTENSION

Endothelin receptor antagonist has limited access to the fetal compartment during chronic maternal administration late in pregnancy

(2012) Larry G. Thaete et al.   LIFE SCIENCES

Review: Does size matter? Placental debris and the pathophysiology of pre-eclampsia

(2012) C.W.G. Redman et al.   PLACENTA

Endothelin: Key Mediator of Hypertension in Preeclampsia

(2011) E. M. George et al.   AMERICAN JOURNAL OF HYPERTENSION

Endothelin type A receptor antagonist attenuates placental ischemia–induced hypertension and uterine vascular resistance

(2011) Kiran B. Tam Tam et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Maternal vasodilation in pregnancy: the emerging role of relaxin

(2011) Kirk P. Conrad   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Angiogenic Growth Factors Are New and Essential Players in the Sustained Relaxin Vasodilatory Pathway in Rodents and Humans

(2011) Jonathan T. McGuane et al.   HYPERTENSION

The Vascular Endothelial Growth Factor Receptor Inhibitor Sunitinib Causes a Preeclampsia-Like Syndrome With Activation of the Endothelin System

(2011) Mariëtte H.W. Kappers et al.   HYPERTENSION

Sunitinib-Induced Systemic Vasoconstriction in Swine Is Endothelin Mediated and Does Not Involve Nitric Oxide or Oxidative Stress

(2011) Mariëtte H.W. Kappers et al.   HYPERTENSION

The relationship between circulating endothelin-1, soluble fms-like tyrosine kinase-1 and soluble endoglin in preeclampsia

(2011) P K Aggarwal et al.   JOURNAL OF HUMAN HYPERTENSION

Autoantibody-Mediated IL-6-Dependent Endothelin-1 Elevation Underlies Pathogenesis in a Mouse Model of Preeclampsia

(2011) C. C. Zhou et al.   JOURNAL OF IMMUNOLOGY

Immunology of Pre-Eclampsia

(2010) Christopher W. G. Redman et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice

(2010) Janice Schildroth et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Ambrisentan, an endothelin receptor type A-selective endothelin receptor antagonist, for the treatment of pulmonary arterial hypertension

(2009) Martha Kingman et al.   EXPERT OPINION ON PHARMACOTHERAPY

Hypertension in Response to Autoantibodies to the Angiotensin II Type I Receptor (AT1-AA) in Pregnant Rats

(2009) Babbette LaMarca et al.   HYPERTENSION

Role of Endothelin in Mediating Soluble fms-Like Tyrosine Kinase 1–Induced Hypertension in Pregnant Rats

(2009) Sydney R. Murphy et al.   HYPERTENSION