Article
Pharmacology & Pharmacy
Yuting Wang, Jingjing Xuan, Guangchao Zhao, Dandan Wang, Na Ying, Jie Zhuang
Summary: This study developed a NCs/MPs technology to improve the dissolution and oral absorption of poorly soluble drugs. By encapsulating nanocrystals in microparticles, the technology successfully enhanced drug release in intestinal fluid and significantly improved oral bioavailability, offering a promising and effective approach for enhancing the solubility of poorly soluble drugs.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Polymer Science
Rongguan Yin, Yuqi Zhao, Adam Gorczynski, Grzegorz Szczepaniak, Mingkang Sun, Liye Fu, Khidong Kim, Hanshu Wu, Michael R. Bockstaller, Krzysztof Matyjaszewski
Summary: An alternating P-(MMA/BA) copolymer was synthesized using the ARGET ATRP method, and subsequent postpolymerization modifications were performed. The modified copolymer showed different architecture compared to gradient and statistical copolymers, with a narrower range of glass transition.
Article
Multidisciplinary Sciences
Young Hwan Park, Jeong Seok Choi, Jung Woo Choi, Hak Jun Kim
Summary: This study investigated the incidence and risk factors of allergic contact dermatitis (ACD) after using 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives. The incidence of ACD from both adhesives was around 2-3%, with no significant difference between them. Logistic regression analysis did not identify any variables that increased the risk of ACD for either adhesive, suggesting that clinicians and patients should be aware of the possibility of ACD even without known risk factors.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Gang Du, Du Kong, Binyao Shi, Zhengchen Jiang, Muguo Aniu, Jinhuan Yang, Hao Zhang, Li Gao, Bin Jin
Summary: The study investigated the safety, feasibility, and effectiveness of liver retraction using NBCA glue during LC for patients with thick protrusion hepatic quadrate lobe. Results showed that using NBCA to fix the liver protrusion can shorten the operation time and does not lead to significant complications.
Article
Clinical Neurology
Thomas W. Lategan, Laurene Wang, Tiffany N. Sprague, Franck S. Rousseau
Summary: The study confirmed the bioequivalence between two Bafiertam(TM) capsules and one Tecfidera(R) capsule, both of which were found to be safe and generally well tolerated.
Article
Agriculture, Dairy & Animal Science
Jun-Cheng Chen, Fang Yang, Ming-Hui Duan, Ze-En Li, Yan Dai, Mei Zhang, Fan Yang
Summary: This study aimed to determine the pharmacokinetics of meloxicam in pigeons. The results showed that meloxicam was effectively and quickly absorbed after oral and intramuscular administration, with high bioavailability. After intravenous administration, the elimination was faster. Formulating a dosing regimen for pigeons presented a significant challenge due to the lack of a precise analgesic threshold and notable differences in analgesic thresholds among various animal species. Higher doses or shorter dosing intervals are recommended for treating pain in pigeons, but further research is required to verify these recommendations.
Article
Fisheries
Ning Xu, Weiyu Sun, Lve Gong, Yongtao Liu, Jing Dong, Yibin Yang, Shun Zhou, Xiaohui Ai
Summary: This study investigated the pharmacokinetic properties of doxycycline in crayfish and found that multiple-peak phenomenon occurred in hemolymph and tissues regardless of the drug administration route. The pharmacokinetic parameters were altered with different administration methods.
Editorial Material
Neuroimaging
Rimal H. Dossani, Muhammad Waqas, Hamid H. Rai, Ammad A. Baig, Justin M. Cappuzzo, Adnan H. Siddiqui, Elad Levy
Summary: This article presents the principles of using nBCA for tumor embolization in a patient with a history of word-finding difficulty and memory loss. The patient underwent successful embolization using nBCA and subsequent resection of the meningioma with minimal complications.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Biochemistry & Molecular Biology
Olivier Chevallier, Patricia Fauque, Carole Poncelet, Kevin Guillen, Pierre-Olivier Comby, Karine Astruc, Julie Barberet, Nicolas Falvo, Emmanuel Simon, Romaric Loffroy
Summary: The use of NBCA glue as an embolic agent for varicocele embolization in infertile men shows significant improvement in semen parameters, especially for patients with abnormal sperm count.
Article
Pharmacology & Pharmacy
Yaquelin Ramos Carriles, Mona Suetel, Sebastian Henze, Ruben Alvarez Brito, Wolf-Dieter Mueller
Summary: The study aimed to develop novel PBCA nanofiber meshes for drug delivery and tissue engineering, showing that PBCA nanofibers produced through electrospinning exhibited good morphology and mechanical properties, making them suitable for drug delivery carriers and tissue engineering scaffolds.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Microbiology
Aline Barth, Mohammad Hossain, Darin B. Brimhall, Caroline R. Perry, Courtney A. Tiffany, Sherry Xu, Etienne F. Dumont
Summary: Gepotidacin is a promising novel antibiotic for antibiotic-resistant pathogens. Pharmacokinetic evaluations showed that its mesylate salt tablet formulation had good characteristics and was effective in both adults and adolescents. Safety profiles were similar between the two age groups.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2022)
Article
Pharmacology & Pharmacy
Ruchira Salunkhe, Chhaya Gadgoli, Archana Naik, Nikita Patil
Summary: This study aimed to determine the bioavailability and pharmacokinetic profile of three markers in antidiabetic herbal drugs and found that diosgenin and charantin have lower bioavailabilities compared to hydroxychalcone. The addition of piperine significantly increased the bioavailabilities of all three marker compounds.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Chemistry, Physical
Min-Jun Baek, Hyeon-Jong Shin, Ju-Hwan Park, Jaehwan Kim, Il-Mo Kang, Jangik I. Lee, Dae-Duk Kim
Summary: In this study, a doxazosin-bentonite (DXBT) composite formulation for controlled oral delivery was prepared and characterized, and the pharmacokinetics of doxazosin in rats was evaluated. The DXBT composite showed pH-dependent controlled-release profiles, making it a potential oral drug delivery platform.
APPLIED CLAY SCIENCE
(2022)
Review
Pharmacology & Pharmacy
P. Macheras, A. A. Tsekouras
Summary: The assumption of infinite time for oral drug absorption has had a significant impact on the study of bioavailability and bioequivalence. However, it has been revealed that drug absorption has a finite time period, calling for regulatory changes in assessment methods.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Pharmacology & Pharmacy
Radni D. Deshpande, Devanshi S. Shah, Sharda Gurram, Durgesh K. Jha, Paramita Batabyal, Purnima D. Amin, Sadhana Sathaye
Summary: This study successfully developed formulated oral PHL granules with good stability, favorable pharmacokinetic properties, and retained antioxidant properties of PHL.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Biochemistry & Molecular Biology
Huma Mahmood, Ikram Ullah Khan, Muhammad Asif, Rizwan Ullah Khan, Sajid Asghar, Ikrima Khalid, Syed Haroon Khalid, Muhammad Irfan, Fauzia Rehman, Yasser Shahzad, Abid Mehmood Yousaf, Adnan Younus, Zahid Rasul Niazi, Muhammad Asim
Summary: The study reported the co-encapsulation of ofloxacin with tea tree or lavender oil in gellan gum based hydrogel films using the solvent casting ionotropic gelation method, showing superior antibacterial and wound healing activity. In vitro release studies demonstrated controlled release of the drug and oils from the films over 48 hours.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Applied
Mei Zhang, Sajid Asghar, Cihui Tian, Ziyi Hu, Qineng Ping, Zhipeng Chen, Feng Shao, Yanyu Xiao
Summary: The study developed reduction-sensitive dual-targeting nanogels for glioma therapy, showing excellent drug release and cytotoxicity, providing a novel solution for glioma treatment.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Medicinal
Ling Lin, Sajid Asghar, Lin Huang, Ziyi Hu, Qineng Ping, Zhipeng Chen, Feng Shao, Yanyu Xiao
Summary: The study aimed to enhance the water solubility and oral bioavailability of Chl through a self-microemulsifying drug delivery system (Chl-SMEDDS). The optimized formulation showed stable physical characteristics and improved drug dispersion, with the main absorption site in the duodenum, suggesting that SMEDDS could be an effective strategy for Chl oral administration.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
(2021)
Article
Nanoscience & Nanotechnology
Lei Zhang, Fengjun He, Lina Gao, Minghui Cong, Juan Sun, Jialu Xu, Yutong Wang, Yang Hu, Sajid Asghar, Lihong Hu, Hongzhi Qiao
Summary: This study presents a promising functional nano platform derived from edible Asparagus cochinchinensis that can be utilized in anti-tumor therapy with minimal side effects.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Nanoscience & Nanotechnology
Mehreen Bashir, Junaid Ahmad, Muhammad Asif, Salah-Ud-Din Khan, Muhammad Irfan, Asim Y. Ibrahim, Sajid Asghar, Ikram Ullah Khan, Muhammad Shahid Iqbal, Abdul Haseeb, Syed Haroon Khalid, Mohammed A. S. Abourehab
Summary: Rheumatoid arthritis is an autoimmune disorder that can be effectively treated topically using nanoemulgel formulations, with DIF-IC formulated with XG showing improved efficacy.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Chemistry, Multidisciplinary
Shanshan Zhang, Sajid Asghar, Chenqi Zhu, Junxiu Ye, Ling Lin, Liu Xu, Ziyi Hu, Zhipeng Chen, Feng Shao, Yanyu Xiao
Summary: This study presents a multi-functional delivery system (APND-3) designed to address the issues of poor drug delivery to the brain in Alzheimer's disease (AD) treatment. The system, based on a novel peptide (MOP) with self-assembling properties, significantly enhances the delivery of MOP to the brain, reducing A beta deposition and improving neurological outcomes in AD model mice.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Polymer Science
Nyla Ajaz, Ikram Ullah Khan, Sajid Asghar, Syed Haroon Khalid, Muhammad Irfan, Muhammad Asif, Shahzad Ali Shahid Chatha
Summary: A dual responsive semi-IPN hydrogel was developed by free radical polymerization, which showed optimal drug release at pH 7.4. Toxicological and hemocompatibility tests confirmed the biocompatibility of the material.
JOURNAL OF POLYMER RESEARCH
(2021)
Article
Cell Biology
Fizza Abdul Razzaq, Muhammad Asif, Sajid Asghar, Muhammad Shahid Iqbal, Ikram Ullah Khan, Salah-Ud-Din Khan, Muhammad Irfan, Haroon Khalid Syed, Ahmed Khames, Hira Mahmood, Asim Y. Ibrahim, Amani M. El Sisi
Summary: The study aimed to investigate a transdermal delivery system for glimepiride using nanoemulgel formulation and a combination with anti-diabetic oil, which enhanced drug permeation and hypoglycemic activity.
Review
Pharmacology & Pharmacy
Sajid Asghar, Ikram Ullah Khan, Saad Salman, Syed Haroon Khalid, Rabia Ashfaq, Thierry F. Vandamme
Summary: This review discusses the threat of microbial infections throughout human civilization and the recent surge in resistant microbial strains. It explores the potential of combining plant phytochemicals with nanotechnological innovations to combat drug resistance and biofilms. The ineffectiveness of current antibiotic regimens, the challenges of phytochemical commercialization, and the advantages of nanosized systems in improving drug delivery are also highlighted.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Article
Polymer Science
Rabia Munir, Abdul Hadi, Salah-ud-Din Khan, Sajid Asghar, Muhammad Irfan, Ikram Ullah Khan, Misbah Hameed, Sana Inam, Nayyer Islam, Shahzadi Filza Hassan, Memoona Ishtiaq, Pervaiz Akhtar Shah, Muhammad Shahid Iqbal, Haroon Khalid Syed, Ahmed Khames, Mohammad A. S. Abourehab
Summary: This study aimed to improve the dissolution and solubility of dexibuprofen (DEX) using hydroxypropyl beta cyclodextrin (HP beta CD) inclusion complexes, and evaluate the effect of hydrophilic polymers on the solubilization efficiency of HP beta CD. The kneading method at a DEX/HP beta CD (1:4) weight ratio showed the highest solubility and drug release. The addition of hydrophilic polymers, poloxamer-188 (PXM-188) and poloxamer-407 (PXM-407) significantly enhanced the complexation efficiency and solubility of DEX/HP beta CD. It was concluded that PXM-188 at a weight ratio of 10.0% w/w was the best candidate for improving solubility, stability, and release rate of DEX.
Article
Pharmacology & Pharmacy
Hira Mahmood, Muhammad Asif, Syed Haroon Khalid, Ikram Ullah Khan, Zunera Chauhdary, Fizza Abdul Razzaq, Sajid Asghar
Summary: In this study, a composite functional wound dressing based on kappa-carrageenan and tannic acid was prepared and co-encapsulated with simvastatin and Geranium oil. The prepared films had excellent mechanical strength, high swelling rate, and good water solubility. The dressing showed superior antioxidant, anti-inflammatory, and broader anti-bacterial activity. The CS/G/TA hydrogel film exhibited excellent wound healing effect through improved angiogenesis and down regulation in the expression of inflammatory markers.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Nida Rashid, Syed Haroon Khalid, Ikram Ullah Khan, Zunera Chauhdary, Hira Mahmood, Ayesha Saleem, Muhammad Umair, Sajid Asghar
Summary: Curcumin (Cur) entrapped poly(vinyl alcohol) (PVA)/gelatin composite films cross-linked with tannic acid (TA) were developed as bioactive dressings for accelerated wound healing. The films demonstrated excellent mechanical strength, swelling ability, water vapor transmission rate, solubility, and sustained drug release. Moreover, the films exhibited antioxidant and antibacterial effects, promoted wound healing and inhibited inflammation. Therefore, Cur-loaded composite films could serve as an effective delivery system for wound healing.
Review
Biochemistry & Molecular Biology
Rabia Ashfaq, Akhtar Rasul, Sajid Asghar, Anita Kovacs, Szilvia Berko, Maria Budai-Szucs
Summary: Nano-scale bioactive colloidal carrier systems, such as lipid nanoparticles (LNPs), have shown great potential in overcoming challenges associated with disease treatments. LNPs not only improve the pharmacokinetics and stability of encapsulated compounds, but also provide efficient targeting and reduced toxicity. However, the poor solubility, stability, and absorption of natural therapeutic molecules have hindered research in the nutraceutical sector. Loading these molecules into LNPs offers a promising solution by utilizing their ability to accommodate both hydrophilic and hydrophobic molecules.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Polymer Science
Tayyaba Sadiq, Syed Haroon Khalid, Ikram Ullah Khan, Hira Mahmood, Sajid Asghar
Summary: In this study, biocomposite hydrogel films made from flaxseed gum (FSG)/kappa carrageenan (CGN) were fabricated and loaded with an iron chelator to promote wound healing. The films were characterized and tested for their properties and release of the drug. In vivo testing showed promising results for wound contraction. The optimized biocomposite hydrogel film showed potential for wound healing applications.
Article
Polymer Science
Nyla Ajaz, Ikram Ullah Khan, Muhammad Irfan, Syed Haroon Khalid, Sajid Asghar, Yasir Mehmood, Muhammad Asif, Usra, Ghulam Hussain, Yasser Shahzad, Shefaat Ullah Shah, Muhammad Usman Munir
Summary: The study successfully developed hydroxy propyl beta-cyclodextrin-g-poly(acrylic acid)/gelatin semi-interpenetrating networks for the colonic delivery of dexamethasone sodium phosphate. The optimized hydrogel formulation showed pH-dependent swelling and mucoadhesive properties, with in vitro drug release assay demonstrating pH-dependent release of dexamethasone sodium phosphate. Overall, the prepared semi-IPN hydrogel exhibited biocompatible nature and potential for colonic drug delivery.
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
