Article
Chemistry, Applied
Kepeng Hu, Erna Jia, Qimeng Zhang, Wei Zheng, Rongjiao Sun, Mengao Qian, Ying Tan, Wanle Hu
Summary: Tea tree oil (TTO) is encapsulated into the hydrogel network via a previous emulsification process, and a tough and antibacterial injectable hydrogel is synthesized by the Schiff base reaction between carboxymethyl chitosan (CMCS) and genipin (GP). The obtained hydrogels exhibit high adhesive strength (about 162.75 kPa), excellent antibacterial properties (over 90%), and great biocompatibility. The heterogeneous hydrogel shows good slow-release properties of TTO for accelerated healing of complex anal fistula wounds according to an anal fistula-like wound healing experiment.
CARBOHYDRATE POLYMERS
(2023)
Article
Biochemistry & Molecular Biology
Giuseppina Biscari, Yanmiao Fan, Faridah Namata, Calogero Fiorica, Michael Malkoch, Fabio Salvatore Palumbo, Giovanna Pitarresi
Summary: This study develops hybrid hydrogels based on the formation of a polyelectrolyte complex between dopamine-functionalized Gellan Gum and the TMP-G2-alanine dendrimer. The hydrogels can be doubly crosslinked with CaCl2 to obtain solid hydrogels, or oxidized to obtain injectable hydrogels. The hydrogels exhibit cell viability up to 100% and broad-spectrum antimicrobial activity.
MACROMOLECULAR BIOSCIENCE
(2023)
Review
Pharmacology & Pharmacy
Gianina Dodi, Rosina E. Sabau, Bianca E. -B. Cretu, Ioannis Gardikiotis
Summary: This review aims to evaluate the antioxidant properties of gellan and guar gums in wound healing. It is found that wound-healing dressings based on gellan gum possess significant antioxidant properties, while the antioxidant properties of guar gum are often overlooked, despite their potential in improving wound healing outcomes. Further research is needed to develop customized wound dressings that can scavenge excess reactive oxygen species, especially in clinical practice.
Article
Biochemistry & Molecular Biology
Hemant Singh, Indu Yadav, Wajid Mohammad Sheikh, Aniruddha Dan, Zenab Darban, Showkat Ahmad Shah, Narayan Chandra Mishra, Syed Shahabuddin, Shabir Hassan, Showkeen Muzamil Bashir, Mukesh Dhanka
Summary: This research focuses on fabricating biological macromolecule-based hydrogel with desirable antibacterial, antioxidant, controlled drug release, cytocompatibility, and wound healing properties. The nanocomposite hydrogel loaded with 500 mu g/ml NC exhibited excellent performance in treating full-thickness wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Aznatul Jannah Abu Bakar, Nurul Shahirah Mohd Azam, Vigneswari Sevakumaran, Wan Iryani Wan Ismail, Mohd Hasmizam Razali, Saiful Izwan Abdul Razak, Khairul Anuar Mat Amin
Summary: Gellan gum/ collagen (GG/C) hydrogel films containing gatifloxacin (GAT) were developed and investigated for their properties as wound dressing materials. The materials showed excellent mechanical properties and 100% drug release after 40 minutes. They exhibited strong antibacterial activities against various bacteria and demonstrated promising results in in-vivo cytotoxicity assessments. The study highlights the potential of these materials to be used as effective wound dressings.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Wenqiang Li, Xingling Jian, Yanfen Zou, Lin Wu, Haiyan Huang, Hui Li, Dandan Hu, Bo Yu
Summary: The Mg2+@PAM/GG hydrogel synthesized by chemical crosslinking and Mg2+ ion immersion techniques showed enhanced mechanical strength and biocompatibility for skin burn wound healing. In vitro experiments demonstrated its promotion of fibroblast cell proliferation and inhibition of NF-κB pathway. Animal studies confirmed its ability to accelerate wound healing with sustained-released Mg2+ ions, indicating its potential as a commercial application for full-thickness burn healing materials.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Jiahui Guo, Yunru Yu, Yingbo Shen, Xiaoyan Sun, Yan Bi, Yuanjin Zhao
Summary: Novel bioactive gellan gum microfibers loaded with antibacterial peptides and vascular endothelial growth factor are proposed for wound healing using microfluidic spinning. The bioactive microfibers obtained through microfluidics have uniform morphologies. The loaded antibacterial peptides effectively target bacteria at the wound site, reducing the risk of infection, while the sustained release of vascular endothelial growth factor promotes angiogenesis and wound healing.
Article
Chemistry, Applied
K. M. Kanyuck, T. B. Mills, I. T. Norton, A. B. Norton-Welch
Summary: This study investigated the swelling mechanism of high acyl gellan gum, its impact on hydrogel mechanical properties and drug release. Low ionic strength solutions caused the highest degree of swelling and slowed down glucose release, highlighting the importance of considering these changes in formulation design for functional applications.
CARBOHYDRATE POLYMERS
(2021)
Article
Polymer Science
Muhammad Zulhelmi Muktar, Muhammad Ameerul Amin Bakar, Khairul Anuar Mat Amin, Laili Che Rose, Wan Iryani Wan Ismail, Mohd Hasmizam Razali, Saiful Izwan Abd Razak, Marc in het Panhuis
Summary: The study developed wound dressing materials using gellan gum and virgin coconut oil, examining their chemical interaction, mechanical performance, physical properties, and thermal behavior. The results showed that the stress-at-break and Young's modulus of the GVCO hydrogel increased with the inclusion of VCO microemulsion, suggesting its potential as a biomedical material.
Article
Chemistry, Applied
Zhiping Fan, Ping Cheng, Yan Gao, Dawei Wang, Guangwei Jia, Pan Zhang, Sangeeta Prakash, Zhengping Wang, Jun Han
Summary: This research highlights the engineering of novel composite hydrogels from natural polysaccharides Salecan and Gellan using physical methods, without any structural modification or chemical crosslinking. The rheological properties of the hydrogels were investigated and key parameters were explored and compared using different models like Power Law, Herschel-Bulkley, and Arrhenius. This study reports the development of a novel composite hydrogel with ideal elasticity, injectability, good thermostability, and self-recovery, paving the way for its application in various fields.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Maryam Sahraro, Mehdi Barikani, Hamed Daemi, Payam Baei
Summary: In this study, multifunctional polyurethane nanoparticles (MPUNs) were embedded into methacrylated gellan gum to prepare stimuli-responsive hydrogels with improved mechanical properties. The optimized formulation showed excellent compression strength and ultimate strain, as well as the ability to restore its original shape after repeated compression tests. The hydrogels exhibited a dual physical and chemical crosslinking mechanism and were found to be non-toxic to human dermal fibroblast cells, making them suitable for soft tissue engineering applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Applied
Linyuan Liu, Duoduo Zhang, Xiaoxiao Song, Mi Guo, Ziwei Wang, Fang Geng, Xingtao Zhou, Shaoping Nie
Summary: In this study, the encapsulation of anthocyanins with Gelatin/Gellan gum was investigated to protect anthocyanins from degradation in the stomach and enhance their release in the small intestine. The results showed that Gelatin/Gellan gum = 8/2 had the most compact and stable structure, and the compound hydrogels did not inhibit the proliferation of normal rat intestinal epithelial cells (IEC-6), indicating the effectiveness and safety of this method.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Peng Wang, Zhi-gang Luo, Zhi-gang Xiao, Ahmed S. M. Saleh
Summary: Oxidized gellan gum (OGG) hydrogel beads were used as delivery systems for resveratrol. The degree of oxidation (DO) and CaCl2 concentration had significant effects on the formation and functional properties of hydrogel beads. The resveratrol encapsulation efficiency and loading capacity of OGG hydrogel beads increased with higher DO. The hydrogel beads showed a uniform spherical shape and were formed through hydrogen bonds and ionic interaction. Encapsulation of resveratrol changed its physical state from crystalline to amorphous form. Hydrogel beads fabricated with DO80 OGG and 1.0 M CaCl2 provided high protection and maintained the antioxidant capacity of resveratrol. DO and CaCl2 concentrations controlled the in-vitro release behaviors of hydrogel beads and achieved targeted release of resveratrol in the small intestine.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Zahra Shahravi, Mehdi Mehdikhani, Mohammad Amir Amirkhani, Mahsa Mollapour Sisakht, Shadi Farsaei
Summary: A novel drug-loaded nanofibrous membrane composed of PVA/GG and PCL was fabricated for wound healing. The scaffold showed suitable morphology, mechanical properties, and drug delivery capabilities.
Article
Polymer Science
Shuwen Zhou, Xinmeng Zheng, Ke Yi, Xuancheng Du, Cheng Wang, Pengfei Cui, Pengju Jiang, Xinye Ni, Lin Qiu, Jianhao Wang
Summary: This study synthesized a glutathione-gellan gum conjugate (GSH-GG) as a responsive gelling material for delivering doxorubicin hydrochloride (DOX) for cancer therapy. DOX-loaded GSH-GG showed temperature-ion dual responsive gelling property and lower drug release under acidic conditions, with selective action on cancer cells and potential for complete inhibition of tumor progression.
Article
Business
Shiyue Luo, Nafisa Yimamu, Yueran Li, Haitao Wu, Muhammad Irfan, Yu Hao
Summary: In the context of sustainable development, the development of the digital economy can improve green innovation levels indirectly by boosting economic openness, optimizing industrial structure, and expanding market potential. The development of the digital economy has spatial effects on green innovation. However, the enhancement of green innovation in more developed regions may inhibit green innovation in less developed regions.
BUSINESS STRATEGY AND THE ENVIRONMENT
(2023)
Article
Environmental Sciences
Jianmin Liu, Yan Xue, Zehong Mao, Muhammad Irfan, Haitao Wu
Summary: This paper examines the relationship between export sophistication and total factor energy efficiency (TFEE) and finds that an improvement in export sophistication leads to higher TFEE. The findings have important implications for supporting China's export sophistication promotion strategy and for energy efficiency improvement and energy crisis response in the post-pandemic era.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Green & Sustainable Science & Technology
Yuanxiong Lin, Muhammad Khalid Anser, Michael Yao-Ping Peng, Muhammad Irfan
Summary: Carbon emissions are harmful to the environment and expensive. The role of financial institutions is increasingly important as pollution emissions rise. By utilizing a novel econometric model, this study assessed the impact of green financing, renewable energy, trade openness, industrial upgradation, and financial development on carbon neutrality using data from Chinese cities between 2000 and 2020. The conclusions indicate that investments in green finance, renewable energy, and financial development can decrease CO2 emissions, while variables such as economic growth, energy consumption, trade, and foreign direct investment can increase CO2 emissions. Sustainable growth is crucial in helping China achieve its carbon neutrality goals. The immediate effects of green financing through renewable energy are temporary, but the direct impact of funding green initiatives is more long-lasting and critical for carbon neutrality.
Article
Chemistry, Physical
Mohammed Jalalah, Zubair Nabi, Muhammad Naveed Anjum, Mirza Nadeem Ahmad, Atta Ul Haq, Muhammad Bilal Qadir, Mohd Faisal, Mabkhoot Alsaiari, Muhammad Irfan, Farid A. Harraz
Summary: The growing industry and its effluents, such as toxic dyes and volatile organic compounds, pose a serious environmental concern due to their non-biodegradable nature and high chemical stability. Recently, using photo-catalysts to degrade toxic dyes and drugs has become an important and successful approach. This study presents the synthesis of a poly(o-anisidine)-based composite with graphitic carbon nitride and zinc oxide (POA/g-C3N4/ZnO) and its utilization as a photo-catalyst.
Article
Green & Sustainable Science & Technology
Jin Hu, Hong Zhang, Muhammad Irfan
Summary: Digital infrastructure construction and low-carbon development are two important drivers for sustainable growth. This study comprehensively analyzes the relationship between the two, using China as an example to empirically examine the role of digital infrastructure construction in low-carbon development. The results show that digital infrastructure construction actively encourages low-carbon growth and has a positive spatial spillover impact. The study also highlights the non-linear trend of increasing marginal effect and the need for industrial upgrading in low-carbon development.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Respiratory System
Russell Seth Martins, Hawra Hussain, Maryam Chaudry, Nashia Ali Rizvi, Mohsin Ali Mustafa, Bushra Ayub, Salima Saleem Aamdani, Alina Abdul Rehman, Alina Pervez, Sarah Nadeem, Rameesha Khalid, Akbar Shoukat Ali, Shayan Shahid, Ali Bin Sarwar Zubairi, Adil H. H. Haider, Muhammad Irfan
Summary: This study developed evidence-based clinical practice guidelines and clinical pathways for the management of chronic respiratory conditions in Pakistan, aiming to improve the primary care management of these diseases.
BMC PULMONARY MEDICINE
(2023)
Correction
Environmental Sciences
Qing Wei, Wendong Xiao, Rana Muhammad Shahid Yaqub, Muhammad Irfan, Muhammad Murad, Muhammad Zafar Yaqub
FRONTIERS IN ENVIRONMENTAL SCIENCE
(2023)
Article
Water Resources
Muhammad Irfan, Sri Safrina, Erry Koriyanti, Netty Kurniawati, Khairul Saleh, Iskhaq Iskandar
Summary: This study aims to investigate the impact of climate anomalies in 2019 and 2020, as well as factors such as rainfall, groundwater level, and soil moisture on peatland natural disasters in South Sumatra. The results show that in the 2019 dry season, there was minimal rainfall, the lowest groundwater table depth was -1.14 m, and the lowest soil moisture was 3.4%. In the 2020 dry season, rainfall exceeded the monthly average of 100 mm, with the lowest groundwater level at -0.44 m and the lowest soil moisture at 26.64%. There is a strong correlation between soil moisture and groundwater table depth, especially when there is less rainfall.
JOURNAL OF GROUNDWATER SCIENCE AND ENGINEERING
(2023)
Article
Biodiversity Conservation
Jin Hu, Yuntao Wu, Muhammad Irfan, Mingjun Hu
Summary: This study evaluates the impact of the ecological civilization pilot policy (ECPP) on industrial structure transformation and explores the mechanism channels and spatial effects using the difference-in-differences method, three-stage mediating effect method, and spatial spillover analysis method. The research findings show that the ECPP has promoted the rationalization of industrial structure but has had a negative impact on industrial structure advancement. Positive central-local relationships enhance the trend toward industrial structure rationalization. Moreover, the effect of the ECPP varies depending on population density and environmental pollution.
ECOLOGICAL INDICATORS
(2023)
Article
Environmental Sciences
Muhammad Shoaib, Muhammad Adnan Munir, Muhammad Yasin Naz, Ghulam Abbas, Muhammad Irfan, Saifur Rahman, Abdulnour Ali Jazem Ghanim
Summary: The limited availability of clean water due to worldwide population growth and pollution necessitates the development of rapid water purification techniques. Photocatalytic degradation using the ZnO/MgFe2O4 heterostructure photocatalyst demonstrates high efficiency in eliminating water pollutants. The presence of magnetic ferrite in the heterostructure promotes radiation absorption, reduces electron-hole recombination, and improves charge transfer. The heterostructure photocatalyst also exhibits high stability and easy removal.
WATER AIR AND SOIL POLLUTION
(2023)
Article
Environmental Sciences
Changying Song, Shaofeng Zheng, Qingsong Zhang, Jiajing Wei, Yuehan Chen, Muhammad Irfan
Summary: The purpose of this study is to investigate the theoretical effects of the digital revolution on environmental behavior and performance, and to analyze the role of digitalization in fiscal decentralization. Using research data collected from 1338 pear farmers in China, a structural equation model was developed and analyzed using partial least squares and bootstrapping methods. The results show that the use of the Internet by farmers has a significant positive effect on improving their information literacy, which in turn promotes online sales of pears.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Social Sciences, Interdisciplinary
Muhd Norizam Jamian, Muhammad Irfan, Waqiuddin Hasanudin, Aulia Sari Torodji
Summary: The Malay-Islamic hikayat texts have served as an important means of conveying Islamic teachings in the Malay world since the 15th century. These narrative works focused on promoting Islamic morality and family values, particularly emphasizing the role of the pious wife in creating a happy household. This paper analyzes the portrayal of the pious wife in two Malay-Islamic hikayat texts, namely Hikayat Darmata'siah and Hikayat Perempuan Bernama Latifah, based on the Pengkaedahan Melayu Theory by Hashim Awang. The study finds that these texts highlight the characteristics of a pious wife, including strong religious belief, obedience to her husband, treating him like a king, and lifelong loyalty. Overall, these hikayat texts still hold relevance as a guide for contemporary women.
Article
Chemistry, Analytical
Muhammad Irfan, Ghulam Murtaza, Shangnan Fu, Ailiang Chen, Feng Qu, Xin Su
Summary: Molecular simulations were used to optimize the sensitivity of lateral flow fluorescence strip (LFFS) aptasensors by optimizing the length and sequence of the DNA probes. The simulations revealed that a 30 nt probe maximized hybridization yield and reduced background signals. Based on these findings, a sensitive aptamer-based fluorescent lateral flow strip was developed for rapid detection of Cd2+.
Article
Environmental Sciences
Yuntao Wu, Jin Hu, Muhammad Irfan, Mingjun Hu
Summary: Achieving sustainable economic development and mitigating climate change require effective green transformation management, including incentivizing industrial enterprises to adopt green transformation practices through increased environmental taxes, and providing financial incentives from the central government to local governments.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Computer Science, Information Systems
Fazal Muhammad, Bilal Khan, Rashid Naseem, Abdullah A. Asiri, Hassan A. Alshamrani, Khalaf A. Alshamrani, Samar M. Alqhtani, Muhammad Irfan, Khlood M. Mehdar, Hanan Talal Halawani
Summary: Liver disease is common worldwide, especially among young people. Researchers have used machine learning to analyze models for predicting liver disease in its early stages. The study found that the Random Forest classifier performs well in early diagnosis of liver disease.
CMC-COMPUTERS MATERIALS & CONTINUA
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)