Perturbations in mitochondrial dynamics by p66Shc lead to renal tubular oxidative injury in human diabetic nephropathy

Real-time in vivo mitochondrial redox assessment confirms enhanced mitochondrial reactive oxygen species in diabetic nephropathy

(2017) Daniel L. Galvan et al.   KIDNEY INTERNATIONAL

The hallmarks of mitochondrial dysfunction in chronic kidney disease

(2017) Daniel L. Galvan et al.   KIDNEY INTERNATIONAL

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

(2016) Lena Pernas et al.   Annual Review of Physiology

Mitochondrial Dynamics Is Linked to Longevity and Protects from End-Organ Injury: The Emerging Role of Sirtuin 3

(2016) Ariela Benigni et al.   ANTIOXIDANTS & REDOX SIGNALING

Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes

(2016) M. T. Coughlan et al.   CLINICAL SCIENCE

Clinical Manifestations of Kidney Disease Among US Adults With Diabetes, 1988-2014

(2016) Maryam Afkarian et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy

(2016) Xiaoxuan Xu et al.   Scientific Reports

Sirtuin and metabolic kidney disease

(2015) Shu Wakino et al.   KIDNEY INTERNATIONAL

Extracellular Regulated Kinase Phosphorylates Mitofusin 1 to Control Mitochondrial Morphology and Apoptosis

(2015) Aswin Pyakurel et al.   MOLECULAR CELL

Functional Regulation of Adipose-Derived Stem Cells by PDGF-D

(2015) Ji Hye Kim et al.   STEM CELLS

Disruption of Renal Tubular Mitochondrial Quality Control by Myo-Inositol Oxygenase in Diabetic Kidney Disease

(2014) M. Zhan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?

(2013) G C Higgins et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy

(2013) L. Xiao et al.   DIABETES

Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease

(2013) K. Sharma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

(2013) Ming Zhan et al.   KIDNEY INTERNATIONAL

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

The pathogenic role of the renal proximal tubular cell in diabetic nephropathy

(2012) S. C. W. Tang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc

(2012) F. Bock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Can We Target Tubular Damage to Prevent Renal Function Decline in Diabetes?

(2012) Joseph V. Bonventre   SEMINARS IN NEPHROLOGY

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus

(2011) Sherene M. Shenouda et al.   CIRCULATION

Diabetic kidney disease with and without albuminuria

(2011) Richard J MacIsaac et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins

(2011) Shengnan Wu et al.   FEBS Journal

Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation

(2011) M. G. Pesaresi et al.   HUMAN MOLECULAR GENETICS

Toll-Like Receptor 4 Promotes Tubular Inflammation in Diabetic Nephropathy

(2011) M. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Lifespan-Regulator p66Shc in Mitochondria: Redox Enzyme or Redox Sensor?

(2010) Melanie Gertz et al.   ANTIOXIDANTS & REDOX SIGNALING

Development and Progression of Renal Insufficiency With and Without Albuminuria in Adults With Type 1 Diabetes in the Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complications Study

(2010) M. E. Molitch et al.   DIABETES CARE

Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes

(2010) A. Makino et al.   DIABETOLOGIA

Pathologic Classification of Diabetic Nephropathy

(2010) T. W. C. Tervaert et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cell death: Insights into the ultrastructure of mitochondria

(2010) C. Ulivieri   TISSUE & CELL

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

(2009) Craig Brooks et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

(2008) Tianzheng Yu et al.   CARDIOVASCULAR RESEARCH

Rap1b GTPase Ameliorates Glucose-Induced Mitochondrial Dysfunction

(2008) L. Sun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY